Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SRT_RS03140 Genome accession   NZ_AP014612
Coordinates   595717..596424 (+) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus troglodytae strain TKU 31     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 590717..601424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRT_RS03110 (SRT_05910) - 591215..591403 (+) 189 WP_128833001.1 DNA-directed RNA polymerase subunit beta -
  SRT_RS03115 (SRT_05920) endA 591445..592326 (+) 882 WP_128833002.1 DNA/RNA non-specific endonuclease Machinery gene
  SRT_RS03120 (SRT_05930) - 592390..593040 (-) 651 WP_128833003.1 amino acid ABC transporter permease -
  SRT_RS03125 - 593055..593758 (-) 704 Protein_566 amino acid ABC transporter permease -
  SRT_RS03130 (SRT_05950) - 593776..594587 (-) 812 Protein_567 transporter substrate-binding domain-containing protein -
  SRT_RS03135 (SRT_05960) - 594584..595366 (-) 783 WP_128833004.1 amino acid ABC transporter ATP-binding protein -
  SRT_RS03140 (SRT_05970) vicR 595717..596424 (+) 708 WP_002262930.1 response regulator YycF Regulator
  SRT_RS03145 (SRT_05980) vicK 596417..597769 (+) 1353 WP_128833005.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SRT_RS03150 (SRT_05990) - 597766..598567 (+) 802 Protein_571 MBL fold metallo-hydrolase -
  SRT_RS03155 (SRT_06010) rnc 598640..599368 (+) 729 WP_373276260.1 ribonuclease III -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=66170 SRT_RS03140 WP_002262930.1 595717..596424(+) (vicR) [Streptococcus troglodytae strain TKU 31]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=66170 SRT_RS03140 WP_002262930.1 595717..596424(+) (vicR) [Streptococcus troglodytae strain TKU 31]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGATTTGATTATATTAGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTCAGAAAAAACAGCCACGTTCCAATTATTATGTTATCGGCT
AAAGACAGTGAGTTTGATAAAGTTATTGGTCTTGAAATTGGTGCTGATGACTATGTGACCAAACCTTTTTCTAATCGCGA
ATTGCTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCTGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATTTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAATTA
ACTCACCGTGAGTTTGAGCTGTTGCATCATTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTTACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTACTATATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451

Multiple sequence alignment