Detailed information NTG0066169

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: SRT_RS03115
• Genome accession: NZ_AP014612
• Coordinates: 591445..592326 (+)
• Length: 293 a.a.
• NCBI ID: WP_128833002.1
• Uniprot ID: A0A1L7LI22
• Organism: Streptococcus troglodytae strain TKU 31
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 586445..597326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SRT_RS03085 (SRT_05870)	-	586640..587518 (+)	879	WP_128832998.1	F0F1 ATP synthase subunit gamma	-
SRT_RS03090 (SRT_05880)	atpD	587544..588950 (+)	1407	WP_128832999.1	F0F1 ATP synthase subunit beta	-
SRT_RS03095 (SRT_05890)	-	588964..589380 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
SRT_RS03100	-	589691..589876 (+)	186	WP_373276253.1	DUF1146 family protein	-
SRT_RS03105 (SRT_05900)	murA	589942..591213 (+)	1272	WP_128833000.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SRT_RS03110 (SRT_05910)	-	591215..591403 (+)	189	WP_128833001.1	DNA-directed RNA polymerase subunit beta	-
SRT_RS03115 (SRT_05920)	endA	591445..592326 (+)	882	WP_128833002.1	DNA/RNA non-specific endonuclease	Machinery gene
SRT_RS03120 (SRT_05930)	-	592390..593040 (-)	651	WP_128833003.1	amino acid ABC transporter permease	-
SRT_RS03125	-	593055..593758 (-)	704	Protein_566	amino acid ABC transporter permease	-
SRT_RS03130 (SRT_05950)	-	593776..594587 (-)	812	Protein_567	transporter substrate-binding domain-containing protein	-
SRT_RS03135 (SRT_05960)	-	594584..595366 (-)	783	WP_128833004.1	amino acid ABC transporter ATP-binding protein	-
SRT_RS03140 (SRT_05970)	vicR	595717..596424 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32302.16 Da
• Isoelectric Point: 10.1131

>NTDB_id=66169 SRT_RS03115 WP_128833002.1 591445..592326(+) (endA) [Streptococcus troglodytae strain TKU 31]
MTRKTNKSQRKPQKLYLSLLAALSIFVCTYIATSNHIADSNPIKQAAQLLIGKNKVISSNGSKSHQATPSQELANTVMTD
TVKNALGRRIEWSGAGSFIINHNKTDLNADIASQPYANNQTKVVQGQMVPTVANALLSKMTCQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDRHKRVRY
RVTLIYDSNNNILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=66169 SRT_RS03115 WP_128833002.1 591445..592326(+) (endA) [Streptococcus troglodytae strain TKU 31]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACCGCAAAAATTATACTTATCTCTTCTGGCTGCTTTGAGCATATTTGT
TTGTACTTATATTGCAACCAGTAATCATATTGCTGATAGTAACCCTATAAAACAAGCTGCCCAATTATTGATAGGCAAAA
ATAAGGTCATATCTTCAAATGGATCAAAGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACAGAT
ACAGTAAAAAATGCCTTGGGACGACGAATTGAATGGAGTGGCGCAGGTTCTTTCATTATTAATCATAATAAGACTGATCT
CAATGCTGATATCGCTAGTCAGCCCTATGCCAATAATCAAACTAAGGTAGTACAAGGTCAGATGGTACCAACAGTGGCGA
ATGCTTTGCTGAGTAAAATGACTTGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCAGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATCGTCATAAGCGTGTCCGTTAC
CGTGTGACTCTTATTTATGATAGCAACAATAATATTTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGTAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAGAGCGGTTTGACCTTTGATTATGCGACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (118-251)

3D structure

• AlphaFold DB: A0A1L7LI22

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	61.966	79.863	0.495
endA	Streptococcus pneumoniae D39	61.966	79.863	0.495
endA	Streptococcus pneumoniae R6	61.966	79.863	0.495
endA	Streptococcus pneumoniae TIGR4	61.966	79.863	0.495