Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ML603_RS01605 Genome accession   NZ_CP092887
Coordinates   297799..298560 (+) Length   253 a.a.
NCBI ID   WP_138124792.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 292799..303560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS01590 (ML603_01590) - 293057..294625 (-) 1569 WP_241067386.1 ABC transporter substrate-binding protein/permease -
  ML603_RS01595 (ML603_01595) - 294824..296749 (+) 1926 WP_241067387.1 DUF2207 domain-containing protein -
  ML603_RS01600 (ML603_01600) - 296816..297655 (+) 840 WP_030127654.1 undecaprenyl-diphosphate phosphatase -
  ML603_RS01605 (ML603_01605) mecA 297799..298560 (+) 762 WP_138124792.1 adaptor protein MecA Regulator
  ML603_RS01610 (ML603_01610) - 298567..299736 (+) 1170 WP_241067388.1 MraY family glycosyltransferase -
  ML603_RS01615 (ML603_01615) sufC 299849..300619 (+) 771 WP_003061584.1 Fe-S cluster assembly ATPase SufC -
  ML603_RS01620 (ML603_01620) sufD 300716..301978 (+) 1263 WP_241067389.1 Fe-S cluster assembly protein SufD -
  ML603_RS01625 (ML603_01625) - 302009..303235 (+) 1227 WP_241067390.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29055.68 Da        Isoelectric Point: 4.0755

>NTDB_id=660909 ML603_RS01605 WP_138124792.1 297799..298560(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPEPLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=660909 ML603_RS01605 WP_138124792.1 297799..298560(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCCGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCTAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTCTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.8

98.814

0.64
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482