Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SMUNUM_RS01245 Genome accession   NZ_AP014571
Coordinates   235955..236677 (+) Length   240 a.a.
NCBI ID   WP_002263984.1    Uniprot ID   A0AAX1K0W7
Organism   Streptococcus mutans LP13     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 230955..241677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS01230 (SMNUM_0204) - 231356..232909 (-) 1554 WP_002282744.1 ABC transporter substrate-binding protein/permease -
  SMUNUM_RS01235 (SMNUM_0205) - 233061..234962 (+) 1902 WP_002282743.1 DUF2207 domain-containing protein -
  SMUNUM_RS01240 (SMNUM_0206) - 235020..235865 (+) 846 WP_002275187.1 undecaprenyl-diphosphate phosphatase -
  SMUNUM_RS01245 (SMNUM_0207) mecA 235955..236677 (+) 723 WP_002263984.1 adaptor protein MecA Regulator
  SMUNUM_RS01250 (SMNUM_0208) rgpG 236683..237843 (+) 1161 WP_002262748.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  SMUNUM_RS01255 (SMNUM_0209) sufC 237917..238687 (+) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  SMUNUM_RS01260 (SMNUM_0210) sufD 238725..239987 (+) 1263 WP_002269697.1 Fe-S cluster assembly protein SufD -
  SMUNUM_RS01265 (SMNUM_0211) - 239992..241221 (+) 1230 WP_002282955.1 cysteine desulfurase -
  SMUNUM_RS01270 (SMNUM_0212) sufU 241208..241642 (+) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28028.63 Da        Isoelectric Point: 4.2340

>NTDB_id=65951 SMUNUM_RS01245 WP_002263984.1 235955..236677(+) (mecA) [Streptococcus mutans LP13]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKGETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=65951 SMUNUM_RS01245 WP_002263984.1 235955..236677(+) (mecA) [Streptococcus mutans LP13]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGGACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCCCCGGAGGATTTCTTTAATACCTT
AGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCTGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

99.583

100

0.996
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.571

100

0.496
  mecA Streptococcus pneumoniae D39

48.571

100

0.496
  mecA Streptococcus pneumoniae R6

48.571

100

0.496
  mecA Streptococcus pneumoniae TIGR4

48.571

100

0.496

Multiple sequence alignment