Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ANG_RS09035 Genome accession   NZ_AP013072
Coordinates   1803044..1803796 (-) Length   250 a.a.
NCBI ID   WP_003036395.1    Uniprot ID   I0SDH0
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1798044..1808796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS09015 (ANG_1834) - 1798476..1799708 (-) 1233 WP_025271947.1 cysteine desulfurase -
  ANG_RS09020 (ANG_1835) sufD 1799724..1800986 (-) 1263 WP_003036420.1 Fe-S cluster assembly protein SufD -
  ANG_RS09025 (ANG_1836) sufC 1801026..1801796 (-) 771 WP_025271948.1 Fe-S cluster assembly ATPase SufC -
  ANG_RS09030 (ANG_1837) - 1801887..1803053 (-) 1167 WP_003036405.1 glycosyltransferase family 4 protein -
  ANG_RS09035 (ANG_1838) mecA 1803044..1803796 (-) 753 WP_003036395.1 adaptor protein MecA Regulator
  ANG_RS09040 (ANG_1839) - 1803920..1804762 (-) 843 WP_003036361.1 undecaprenyl-diphosphate phosphatase -
  ANG_RS09045 (ANG_1840) - 1804829..1806718 (-) 1890 WP_025271949.1 DUF2207 domain-containing protein -
  ANG_RS09050 (ANG_1841) - 1806845..1808410 (+) 1566 WP_025271950.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28987.89 Da        Isoelectric Point: 4.1612

>NTDB_id=65543 ANG_RS09035 WP_003036395.1 1803044..1803796(-) (mecA) [Streptococcus anginosus subsp. whileyi MAS624]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDMESEENSDELTQKYIYYIL
KFSSLKEAIVFSKTVDYAVNTSELYKMDDRYYLTILVDIEGRPKRYPAWLLALMREHAEDTDVTRAVLQEHGYLLLVNEA
VASLKKVKCL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=65543 ANG_RS09035 WP_003036395.1 1803044..1803796(-) (mecA) [Streptococcus anginosus subsp. whileyi MAS624]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAGGATTTAGAGGAACGTGGGATGGAAAT
GGCAGATTTTCTCGTTCCACAAGAAAAGACAGAGGAATTTTTCTATGCGATTTTAGATGAGTTGGAAATGCCAGAGAGCT
TTTTAGATAGTGGCATGCTCAGTTTTCGTGTGACACCAAAGCCCGACCGATTGGATGTCTTTGTCACCAAGTCTAAGATT
GATAAGAATTTGAACTTCGATGATTTGGCAGATTTGCCAGATGTAGAAGAGTTGTCTCAAATGTCTCCTGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAGTCAGAGGAAAATAGTGACGAACTAACGCAGAAATATATTTATTACATTTTG
AAATTTTCCAGCCTGAAAGAAGCAATTGTTTTTTCTAAGACAGTAGATTATGCTGTCAATACTTCGGAGTTGTACAAAAT
GGACGACCGCTATTATTTGACAATCTTGGTTGATATTGAAGGGCGTCCAAAGCGTTATCCAGCTTGGCTCCTGGCTTTGA
TGCGTGAACATGCAGAAGATACGGATGTGACAAGAGCTGTTTTGCAAGAGCACGGTTACTTATTGCTTGTCAACGAGGCG
GTTGCCAGTCTTAAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SDH0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.397

98.8

0.656
  mecA Streptococcus pneumoniae D39

66.397

98.8

0.656
  mecA Streptococcus pneumoniae R6

66.397

98.8

0.656
  mecA Streptococcus pneumoniae TIGR4

65.992

98.8

0.652
  mecA Streptococcus mutans UA159

50.201

99.6

0.5
  mecA Streptococcus thermophilus LMD-9

45.49

100

0.464
  mecA Streptococcus thermophilus LMG 18311

45.098

100

0.46

Multiple sequence alignment