Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ANG_RS08875 Genome accession   NZ_AP013072
Coordinates   1765846..1767720 (-) Length   624 a.a.
NCBI ID   WP_003036358.1    Uniprot ID   I0SDF8
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1760846..1772720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS08845 (ANG_1800) - 1761002..1761319 (+) 318 WP_003036352.1 DUF960 domain-containing protein -
  ANG_RS08850 (ANG_1801) - 1761445..1761819 (-) 375 WP_020999484.1 S1 RNA-binding domain-containing protein -
  ANG_RS08855 (ANG_1802) - 1761821..1763221 (-) 1401 WP_003036370.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ANG_RS08860 (ANG_1803) - 1763261..1763893 (-) 633 WP_003036430.1 response regulator transcription factor -
  ANG_RS08865 (ANG_1804) - 1763895..1764890 (-) 996 WP_003036415.1 sensor histidine kinase -
  ANG_RS08870 (ANG_1805) liaF 1764887..1765585 (-) 699 WP_003036398.1 cell wall-active antibiotics response protein LiaF -
  ANG_RS08875 (ANG_1806) stkP 1765846..1767720 (-) 1875 WP_003036358.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ANG_RS08880 (ANG_1807) - 1767717..1768457 (-) 741 WP_003036337.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ANG_RS08885 (ANG_1808) rsmB 1768476..1769789 (-) 1314 WP_003036325.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ANG_RS08890 (ANG_1809) fmt 1769779..1770714 (-) 936 WP_025271941.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67672.80 Da        Isoelectric Point: 9.4881

>NTDB_id=65541 ANG_RS08875 WP_003036358.1 1765846..1767720(-) (stkP) [Streptococcus anginosus subsp. whileyi MAS624]
MIQVGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSVTKSTPTPTKEAVS
SKPTPKPKAKKKRRLRTRYKVLLSAVVLVIVALVALVYLSPSNVKIPDVTGKTVAQARSAIEAAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVAQTP
AAGSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQTPEAGQS
LNLKSDRIVLYVYEPKNEDSSTSESSSQSDSSSDKTSPSSSSSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=65541 ANG_RS08875 WP_003036358.1 1765846..1767720(-) (stkP) [Streptococcus anginosus subsp. whileyi MAS624]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAAAATCATCAAACAAATTGGCCGAGGAGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAATTACCAGACGGATCCGATTG
CTGTAGCGCGTTTTCAAAGAGAGGCGCGAGCCATGGCAGATTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGCCAGCAATATCTAGCAATGGAGTATGTGGCTGGACTTGACTTGAAACGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTGCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCGCATACGCATGGGATTGTTC
ACCGTGATTTAAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACAGACTTTGGGATTGCAGTAGCT
TTTGCAGAAACGAGTTTAACGCAAACCAACTCTATGTTGGGGTCTGTACATTATTTGTCACCAGAACAGGCGCGTGGCTC
AAAAGCAACGGTTCAAAGTGATATTTATGCTATGGGGATTATTTTCTATGAAATGCTAACGGGACACATCCCTTATGATG
GAGATAGTGCTGTTACGATTGCCCTACAACATTTCCAAAAGCCCCTACCGTCTATTATTGCTGAAAATCCAAATGTTCCA
CAGGCATTGGAAAATGTAGTCATCAAGGCAACGGCCAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGTGACGAAGTCAACACCTACTCCTACAAAAGAAGCAGTCAGT
AGTAAGCCTACGCCTAAGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGCTATAAAGTTTTGTTATCAGCGGTGGT
TTTAGTCATCGTAGCTCTGGTGGCTTTAGTCTATTTGAGTCCGTCAAATGTAAAAATACCAGATGTTACTGGAAAAACCG
TTGCGCAAGCACGGTCCGCGATTGAAGCTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGATTCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGGCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCCATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGCTCAAACACCA
GCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGAT
GCCAAGCTATATCGGCTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAACCCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAAACGAAGATTCTTCAACATCTGAAAGTAGTTC
ACAATCTGATAGCAGCTCAGATAAAACTAGCCCATCCTCTAGCAGTTCGTCAACTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(433-500)

PASTA domain (PASTA)

(364-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SDF8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.154

93.75

0.62
  stkP Streptococcus pneumoniae D39

65.812

93.75

0.617
  stkP Streptococcus pneumoniae R6

65.812

93.75

0.617
  stkP Streptococcus pneumoniae Rx1

65.641

93.75

0.615
  pknB Streptococcus mutans UA159

57.166

99.519

0.569
  stkP/pknB Streptococcus salivarius strain HSISS4

54.634

98.558

0.538

Multiple sequence alignment