Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ANG_RS08750 Genome accession   NZ_AP013072
Coordinates   1741149..1742450 (-) Length   433 a.a.
NCBI ID   WP_025271934.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1736149..1747450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS08720 (ANG_1774) - 1736907..1737470 (-) 564 WP_003035207.1 YutD family protein -
  ANG_RS08725 (ANG_1775) sepM 1737608..1738663 (-) 1056 WP_021001375.1 SepM family pheromone-processing serine protease Regulator
  ANG_RS08730 (ANG_1776) coaD 1738644..1739141 (-) 498 WP_003025749.1 pantetheine-phosphate adenylyltransferase -
  ANG_RS08735 (ANG_1777) rsmD 1739131..1739679 (-) 549 WP_025271932.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ANG_RS08740 (ANG_1778) hpf 1739867..1740409 (-) 543 WP_003032381.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ANG_RS08745 (ANG_1779) comFC/cflB 1740487..1741152 (-) 666 WP_025271933.1 ComF family protein Machinery gene
  ANG_RS08750 (ANG_1780) comFA/cflA 1741149..1742450 (-) 1302 WP_025271934.1 DEAD/DEAH box helicase Machinery gene
  ANG_RS08755 (ANG_1781) - 1742507..1743142 (+) 636 WP_003032900.1 YigZ family protein -
  ANG_RS08760 (ANG_1782) cysK 1743241..1744170 (+) 930 WP_003035221.1 cysteine synthase A -
  ANG_RS08765 - 1744235..1744848 (+) 614 Protein_1733 transposase -
  ANG_RS11025 - 1744953..1745222 (+) 270 Protein_1734 IS30 family transposase -
  ANG_RS10740 - 1745399..1746277 (+) 879 Protein_1735 ISAs1 family transposase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49091.04 Da        Isoelectric Point: 8.4623

>NTDB_id=65539 ANG_RS08750 WP_025271934.1 1741149..1742450(-) (comFA/cflA) [Streptococcus anginosus subsp. whileyi MAS624]
MIELQDCLGRMFTKAQLPAELQLYAQTLPAMKEEKGKLCCNRCGQAVDKERHQLPIGAYYCRSCLILGRVRSDEDLYYFP
QEEFPKANVLKWQGKLTEFQAKVSQGLVEAVTKRKDSLVHAVTGAGKTEMIYQVVAQVINQGGAVCLASPRIDVCLELYR
RLKVDFTCDISLLHGESEAYSRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPMLYHAVHQAVKVEGTKIFLTATS
TDELDKKVAKGELTRLSLPRRFHGNPLIVPQKIWLADFQKYLGQKKLVTKLRQFIQKQRKTGFPLLIFASEIRRGQELAE
ILQSNFPNEKVGFVASTTENRLEIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSMD
RPTGELIFFHDGTTMAIEKAIKEIQEMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=65539 ANG_RS08750 WP_025271934.1 1741149..1742450(-) (comFA/cflA) [Streptococcus anginosus subsp. whileyi MAS624]
ATGATAGAATTACAAGATTGCTTAGGCCGTATGTTTACAAAAGCACAACTACCAGCAGAATTGCAATTATATGCGCAAAC
TTTACCAGCAATGAAAGAAGAAAAAGGAAAATTATGTTGCAATCGTTGTGGGCAAGCAGTTGATAAAGAAAGACACCAAC
TGCCAATAGGTGCTTACTACTGTAGATCCTGCTTGATCTTAGGAAGGGTTAGAAGTGATGAAGATCTCTACTATTTTCCA
CAGGAAGAGTTTCCTAAAGCGAATGTCTTGAAATGGCAAGGAAAGTTGACAGAATTTCAAGCTAAGGTTTCTCAAGGACT
TGTAGAGGCGGTTACCAAACGCAAAGATAGCTTGGTTCACGCAGTCACAGGAGCCGGAAAGACGGAAATGATCTATCAGG
TGGTGGCACAAGTCATCAATCAAGGCGGAGCCGTCTGCTTAGCTAGCCCCAGAATTGATGTCTGCTTAGAACTTTATCGC
AGACTGAAAGTAGATTTTACCTGTGATATTTCACTCCTGCACGGCGAATCAGAAGCATATTCCCGCAGTCCTCTCGTGAT
TGCCACCACACATCAGCTTCTCAAATTTTATCAAGCATTTGATCTTCTTATCGTTGATGAAGTAGATGCCTTTCCTTATG
TGGACAATCCGATGCTTTATCATGCAGTTCATCAGGCAGTCAAAGTAGAGGGGACGAAGATTTTCTTAACAGCAACTTCC
ACAGATGAGCTGGATAAAAAAGTGGCTAAAGGAGAATTAACTCGTTTGAGTCTACCCAGACGTTTTCATGGCAATCCTTT
GATTGTTCCGCAAAAAATTTGGTTGGCGGATTTTCAAAAATATCTTGGTCAAAAGAAGCTAGTTACCAAGCTAAGGCAGT
TTATTCAAAAGCAGAGAAAAACAGGATTTCCACTTCTTATTTTTGCTTCCGAGATCAGAAGAGGGCAGGAGCTGGCAGAG
ATTCTCCAAAGCAATTTTCCAAATGAAAAAGTTGGTTTTGTAGCTTCGACGACTGAAAATCGACTAGAAATTGTAGAGAA
GTTTCGTCAAAAAGAAATCACGATTTTGGTAACGACGACGATTTTGGAGCGTGGGGTGACCTTTCCTTGTGTAGATGTTT
TCGTGGTGGAAGCCAACCACCGTCTGTTTAGTCGCAGCGCTCTGGTACAAATCGCTGGACGCGTCGGTCGCAGTATGGAT
CGACCGACAGGCGAGTTAATCTTTTTTCATGATGGTACAACTATGGCGATAGAAAAAGCGATTAAAGAAATTCAGGAGAT
GAATCAGGAGGCCGGTTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(108-245)

Helicase conserved C-terminal domain (Helicase_C)

(290-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

71.963

98.845

0.711
  comFA/cflA Streptococcus pneumoniae D39

71.963

98.845

0.711
  comFA/cflA Streptococcus pneumoniae R6

71.963

98.845

0.711
  comFA/cflA Streptococcus pneumoniae TIGR4

71.729

98.845

0.709
  comFA/cflA Streptococcus mitis NCTC 12261

71.831

98.383

0.707
  comFA/cflA Streptococcus mitis SK321

71.362

98.383

0.702
  comFA Lactococcus lactis subsp. cremoris KW2

56.03

91.917

0.515
  comFA Latilactobacillus sakei subsp. sakei 23K

41.995

99.538

0.418
  comFA Bacillus subtilis subsp. subtilis str. 168

40

92.379

0.37

Multiple sequence alignment