Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OHT52_RS12140 Genome accession   NZ_CP108093
Coordinates   2883864..2884988 (+) Length   374 a.a.
NCBI ID   WP_328720159.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00247     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2878864..2889988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT52_RS12125 (OHT52_12105) - 2879038..2881197 (-) 2160 WP_328720156.1 hypothetical protein -
  OHT52_RS12130 (OHT52_12110) - 2881454..2882287 (-) 834 WP_328720157.1 class I SAM-dependent methyltransferase -
  OHT52_RS12135 (OHT52_12115) radA/sms 2882371..2883783 (+) 1413 WP_328720158.1 DNA repair protein RadA Machinery gene
  OHT52_RS12140 (OHT52_12120) disA 2883864..2884988 (+) 1125 WP_328720159.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OHT52_RS12145 (OHT52_12125) - 2885079..2885918 (-) 840 WP_328720160.1 hypothetical protein -
  OHT52_RS12150 (OHT52_12130) - 2886171..2887076 (+) 906 WP_328720161.1 A/G-specific adenine glycosylase -
  OHT52_RS12155 (OHT52_12135) - 2887174..2887881 (-) 708 WP_328720162.1 M23 family metallopeptidase -
  OHT52_RS12160 (OHT52_12140) - 2888358..2888717 (+) 360 WP_328720163.1 trypco2 family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40273.15 Da        Isoelectric Point: 5.0196

>NTDB_id=653351 OHT52_RS12140 WP_328720159.1 2883864..2884988(+) (disA) [Streptomyces sp. NBC_00247]
MAANDRASSPGKSGQGTGNEALMRASLSAVAPGTALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVMNVEFAATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKSCGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHSELLELAVVARSLGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IMERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=653351 OHT52_RS12140 WP_328720159.1 2883864..2884988(+) (disA) [Streptomyces sp. NBC_00247]
GTGGCAGCCAACGACCGGGCATCATCGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAAGCGCTGATGCGCGCTTCGCT
GAGCGCGGTCGCGCCCGGAACGGCCCTGCGTGACGGACTGGAGCGCATCCTGCGGGGGAACACCGGCGGGCTGATCGTCC
TCGGCATGGACAAGACCGTCGAGTCGATGTGCACCGGCGGTTTCGTGATGAACGTCGAGTTCGCCGCGACCCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGCGCTCATCCTCGACAAGGACATCACCAAGATCCTGCGGGCGGGCGTCCAGCTCGTCCC
GGACGCCTCGATCCCCACCGAGGAGACCGGAACCCGTCACCGCACGGCCGACCGCGTCTCGAAGTCGTGCGGTTTCCCGG
TCGTCTCGGTGTCCCAGTCGATGCGCTTGATCGCGTTGTACGTCGACGGCGAGCGGCGGGTGCTGGAGGAGTCCTCCGCG
ATCCTGTCCCGCGCCAACCAGGCCCTCGCCACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTGACGGCCGTCGCGCAGCGGCTGGAGATGGTGCGCCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTCGGTACCGACGGACGCCTGCTGGCGCTCCAGCTGGACGAGCTGATCGCA
GGCGTGGAGCCGGAGCGGGAGCTCGTCGTACGCGACTACGTCCCCGAGCCGACGGCGAAGCGTTCGCGTACGGTCGCGGA
GGCGCTGACCGAGCTGGACGCGTTGAGCCATTCCGAGCTGCTCGAACTCGCGGTGGTGGCACGGTCGCTGGGGTACAGCG
GTTCGCCCGAGACGCTGGACTCGGCCGTCTCGCCGCGTGGTTTCCGGCTGCTTGCGAAGGTGCCGCGCCTGCCCGGCGCG
ATCATGGAGCGCCTCGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCGGCGAGCGTGGACGACCTCCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGGAGCGTCCGCGAGGGCCTCTCCCGGCTCGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.706

96.524

0.441