Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS40310 Genome accession   NZ_CP108081
Coordinates   9054165..9054821 (-) Length   218 a.a.
NCBI ID   WP_328846521.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9049165..9059821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS40290 (OG718_40275) - 9049344..9050186 (-) 843 WP_143637205.1 hypothetical protein -
  OG718_RS40295 (OG718_40280) - 9050183..9050749 (-) 567 WP_143637201.1 SigE family RNA polymerase sigma factor -
  OG718_RS40300 (OG718_40285) - 9051022..9052473 (+) 1452 WP_143637198.1 NCS2 family permease -
  OG718_RS40305 (OG718_40290) - 9052605..9054056 (-) 1452 WP_143637195.1 penicillin-binding transpeptidase domain-containing protein -
  OG718_RS40310 (OG718_40295) vraR 9054165..9054821 (-) 657 WP_328846521.1 response regulator transcription factor Regulator
  OG718_RS40315 (OG718_40300) - 9054818..9056107 (-) 1290 WP_328846522.1 histidine kinase -
  OG718_RS40320 (OG718_40305) - 9056190..9056399 (-) 210 WP_186001172.1 hypothetical protein -
  OG718_RS40325 (OG718_40310) - 9056617..9057090 (-) 474 WP_328847914.1 GNAT family N-acetyltransferase -
  OG718_RS40330 (OG718_40315) - 9057101..9057874 (-) 774 WP_055616458.1 IclR family transcriptional regulator -
  OG718_RS40335 (OG718_40320) - 9058005..9059534 (+) 1530 WP_143637183.1 aldehyde dehydrogenase (NADP(+)) -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23148.68 Da        Isoelectric Point: 5.1115

>NTDB_id=653044 OG718_RS40310 WP_328846521.1 9054165..9054821(-) (vraR) [Streptomyces sp. NBC_00258]
MTIRIVLADDERMVRTALRAILTAEPDLEVVGEAATGAEAVSVVRGLTPDVVLMDVRMPEIDGIRATEQILATLPDPPRV
VVVTTFENDAYVYEALRAGASGFLLKRTDADSLVQAVRLVAHSDSLLFPAAVRALATEYGRAKAAPPAWVARLTGRESEV
LRLMAAGLTNAEIADRIGVGPATVKTHVAAVLAKTATRDRTQAVIAAYEAGFMKDTAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=653044 OG718_RS40310 WP_328846521.1 9054165..9054821(-) (vraR) [Streptomyces sp. NBC_00258]
ATGACCATCCGGATCGTCCTCGCCGACGACGAGCGCATGGTGCGCACCGCGCTGCGCGCGATCCTGACGGCCGAGCCAGA
TCTGGAGGTCGTCGGCGAGGCGGCCACGGGTGCCGAAGCCGTGTCCGTCGTCCGCGGGCTGACGCCGGACGTCGTCCTCA
TGGACGTCCGTATGCCCGAGATCGACGGCATCCGCGCCACCGAGCAGATCCTGGCGACGCTCCCCGATCCCCCACGCGTC
GTCGTGGTGACCACCTTCGAGAACGACGCGTACGTGTACGAGGCGCTGCGCGCCGGAGCGTCCGGTTTCCTCCTCAAGCG
GACCGACGCCGACTCGCTGGTCCAGGCGGTTCGGCTGGTCGCGCACAGCGACAGCCTGCTGTTCCCCGCGGCGGTGCGTG
CGCTCGCCACCGAGTACGGCCGGGCGAAGGCCGCACCGCCGGCCTGGGTGGCGAGGCTCACCGGCCGGGAGAGCGAGGTC
CTGCGGCTGATGGCCGCCGGGCTCACCAACGCCGAGATCGCCGACCGCATCGGTGTCGGGCCCGCGACGGTGAAGACCCA
TGTGGCGGCCGTCCTGGCGAAGACGGCGACCCGGGACCGTACACAGGCGGTGATCGCGGCGTACGAGGCGGGCTTCATGA
AGGACACGGCCTCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(153-206)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

98.165

0.39
  degU Bacillus subtilis subsp. subtilis str. 168

37.333

100

0.385