Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   L3503_RS06400 Genome accession   NZ_CP091528
Coordinates   1365822..1367972 (-) Length   716 a.a.
NCBI ID   WP_021731916.1    Uniprot ID   I6TUT8
Organism   Lactiplantibacillus paraplantarum strain KCCM 11826P     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1368433..1379311 1365822..1367972 flank 461


Gene organization within MGE regions


Location: 1365822..1379311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3503_RS06400 (L3503_06400) comA 1365822..1367972 (-) 2151 WP_021731916.1 peptide cleavage/export ABC transporter Regulator
  L3503_RS06405 (L3503_06405) plnE 1368238..1368408 (+) 171 WP_003641985.1 two-peptide bacteriocin plantaricin EF subunit PlnE -
  L3503_RS06410 (L3503_06410) plnF 1368433..1368591 (+) 159 WP_033609517.1 two-peptide bacteriocin plantaricin EF subunit PlnF -
  L3503_RS06415 (L3503_06415) - 1368685..1369458 (+) 774 WP_021731918.1 CPBP family intramembrane glutamic endopeptidase -
  L3503_RS06420 (L3503_06420) - 1369762..1370505 (-) 744 WP_021731919.1 response regulator transcription factor -
  L3503_RS06425 (L3503_06425) - 1370625..1371368 (-) 744 WP_021731920.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  L3503_RS06430 (L3503_06430) - 1371369..1372697 (-) 1329 WP_033609518.1 sensor histidine kinase -
  L3503_RS06435 (L3503_06435) - 1372888..1373034 (-) 147 WP_003641979.1 bacteriocin -
  L3503_RS06440 (L3503_06440) - 1373880..1374035 (-) 156 WP_021731922.1 bacteriocin -
  L3503_RS06445 (L3503_06445) - 1374059..1374217 (-) 159 WP_021731923.1 bacteriocin -
  L3503_RS06455 (L3503_06455) - 1375635..1376303 (+) 669 WP_021731924.1 hypothetical protein -
  L3503_RS06460 (L3503_06460) - 1377469..1378740 (-) 1272 WP_021731925.1 glycosyltransferase -
  L3503_RS06465 (L3503_06465) - 1378825..1378986 (-) 162 WP_021731926.1 hypothetical protein -
  L3503_RS06470 (L3503_06470) - 1379027..1379311 (-) 285 WP_021731927.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 79998.75 Da        Isoelectric Point: 6.6531

>NTDB_id=652204 L3503_RS06400 WP_021731916.1 1365822..1367972(-) (comA) [Lactiplantibacillus paraplantarum strain KCCM 11826P]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFEVQDLPL
PFIVHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAMVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAVLSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKLLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHVALLNEHGYYYDLINS

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=652204 L3503_RS06400 WP_021731916.1 1365822..1367972(-) (comA) [Lactiplantibacillus paraplantarum strain KCCM 11826P]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAGACGAGTTTGGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGAGGTCCAAGATTTACCATTG
CCATTTATTGTGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTTGTTGTAAAAACCTCAAAAACGCATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGTTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCCAATAATATGCACAGTACATTGGCGATGGTGGCGATTGGTCTAATTGTTTTTT
ATACTTTTCAAGCTATTTTTACTTATGCCCAGAATTTTTTGTTGGCGGTTTTAGGCCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACCCGGCGGACGGGTGAAATTGTTTCACGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAAAGCAATGCTGTTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTGGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTGTGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAACTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTGAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAACGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTGGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGCGGCTCTGGCAAGTCCACGTTAGTTAAGTTACTTATTGATTTTTATCAGC
CGAATAGTGGTGATGTCATATTGAACGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATATATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACGGATATTAATAAAATGGCCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCACCAGCCCAAGTC
TTGATATTTGATGAGTCGACAAGTGGACTGGATGCAATTACTGAAAAACAATTAATCGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGTTGTCGATTGCGAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGTAGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(5-140)

ABC transporter transmembrane region (ABC_membrane)

(166-436)

ABC transporter (ABC_tran)

(498-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I6TUT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

58.906

99.581

0.587
  comA Streptococcus pneumoniae Rx1

58.626

99.581

0.584
  comA Streptococcus pneumoniae D39

58.626

99.581

0.584
  comA Streptococcus pneumoniae R6

58.626

99.581

0.584
  comA Streptococcus pneumoniae TIGR4

58.485

99.581

0.582
  comA Streptococcus mitis SK321

58.345

99.581

0.581
  comA Streptococcus gordonii str. Challis substr. CH1

57.242

100

0.574
  comA/nlmT Streptococcus mutans UA159

54.875

100

0.55