Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   L3C66_RS01845 Genome accession   NZ_CP091294
Coordinates   392179..394329 (+) Length   716 a.a.
NCBI ID   WP_003641986.1    Uniprot ID   A0AAW3FTH1
Organism   Lactiplantibacillus plantarum subsp. plantarum strain GR1186     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 387179..399329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3C66_RS01815 (L3C66_01815) - 387604..388776 (+) 1173 WP_223843867.1 sensor histidine kinase -
  L3C66_RS01820 (L3C66_01820) - 388777..389520 (+) 744 WP_011100999.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  L3C66_RS01825 (L3C66_01825) - 389639..390382 (+) 744 WP_003641982.1 response regulator transcription factor -
  L3C66_RS01830 (L3C66_01830) - 390687..391460 (-) 774 WP_003646470.1 CPBP family intramembrane glutamic endopeptidase -
  L3C66_RS01835 (L3C66_01835) plnF 391559..391717 (-) 159 WP_003643811.1 two-peptide bacteriocin plantaricin EF subunit PlnF -
  L3C66_RS01840 (L3C66_01840) plnE 391742..391912 (-) 171 WP_003641985.1 two-peptide bacteriocin plantaricin EF subunit PlnE -
  L3C66_RS01845 (L3C66_01845) comA 392179..394329 (+) 2151 WP_003641986.1 peptide cleavage/export ABC transporter Regulator
  L3C66_RS01850 (L3C66_01850) - 394345..394782 (+) 438 WP_236432144.1 hypothetical protein -
  L3C66_RS01855 (L3C66_01855) - 394767..395720 (+) 954 WP_236432145.1 bacteriocin secretion accessory protein -
  L3C66_RS01860 (L3C66_01860) - 395955..396500 (+) 546 WP_003641989.1 CPBP family intramembrane glutamic endopeptidase -
  L3C66_RS01865 (L3C66_01865) - 396567..397235 (+) 669 WP_044429013.1 CPBP family intramembrane glutamic endopeptidase -
  L3C66_RS01870 (L3C66_01870) - 397322..398002 (+) 681 WP_003641991.1 CPBP family intramembrane glutamic endopeptidase -
  L3C66_RS01875 (L3C66_01875) - 398096..398782 (+) 687 WP_044429069.1 CPBP family intramembrane glutamic endopeptidase -
  L3C66_RS01880 (L3C66_01880) - 398940..399230 (+) 291 WP_021356143.1 type II toxin-antitoxin system RelE/ParE family toxin -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 79952.66 Da        Isoelectric Point: 6.6531

>NTDB_id=648973 L3C66_RS01845 WP_003641986.1 392179..394329(+) (comA) [Lactiplantibacillus plantarum subsp. plantarum strain GR1186]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFEVQDLPL
PFIVHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKLLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHAALLNEHGYYYDLINS

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=648973 L3C66_RS01845 WP_003641986.1 392179..394329(+) (comA) [Lactiplantibacillus plantarum subsp. plantarum strain GR1186]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAAACGAGTTTAGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGAGGTACAAGATTTACCATTG
CCATTCATTGTGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTCGTTGTAAAAACCTCGAAAACGCATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGCTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCCAATAATATGCACAGTACATTGGCAGTGGTGGCCATTGGTCTAATCGTTTTTT
ATACCTTTCAGGCTATCTTTACTTATGCCCAGAATTTTTTATTGGCGGTTTTAGGTCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACTCGGCGGACGGGGGAAATTGTTTCGAGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAGAGCAATGCTATTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTAGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTATGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAGCTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTAAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTAGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGTGGCTCTGGCAAGTCCACGTTAGTTAAATTGCTTATTGATTTTTATCAAC
CAAATAGTGGTGATGTCATATTGAATGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATACATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACGGATATTAATAAAATGGCCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCACCCGCTCAAGTC
TTGATATTTGATGAGTCGACGAGTGGACTGGATGCAATTACTGAAAAACAATTAATTGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGTTGTCGATTGCAAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGCGGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(5-140)

ABC transporter transmembrane region (ABC_membrane)

(166-436)

ABC transporter (ABC_tran)

(498-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

58.906

99.581

0.587
  comA Streptococcus pneumoniae D39

58.626

99.581

0.584
  comA Streptococcus pneumoniae R6

58.626

99.581

0.584
  comA Streptococcus pneumoniae Rx1

58.626

99.581

0.584
  comA Streptococcus pneumoniae TIGR4

58.485

99.581

0.582
  comA Streptococcus mitis SK321

58.345

99.581

0.581
  comA Streptococcus gordonii str. Challis substr. CH1

57.103

100

0.573
  comA/nlmT Streptococcus mutans UA159

54.596

100

0.547