Detailed information NTG0648963

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: L3C06_RS12055
• Genome accession: NZ_CP091289
• Coordinates: 2489390..2491582 (-)
• Length: 730 a.a.
• NCBI ID: WP_236360392.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei subsp. paracasei strain GR0562
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2484390..2496582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3C06_RS12025 (L3C06_12025)	-	2484555..2484839 (-)	285	WP_003567331.1	bacteriocin immunity protein	-
L3C06_RS12030 (L3C06_12030)	-	2485033..2485329 (-)	297	WP_236360386.1	bacteriocin immunity protein	-
L3C06_RS12035 (L3C06_12035)	-	2485431..2486786 (-)	1356	WP_236360388.1	threonine/serine ThrE exporter family protein	-
L3C06_RS12040 (L3C06_12040)	-	2487092..2487403 (-)	312	WP_003580849.1	hypothetical protein	-
L3C06_RS12045 (L3C06_12045)	-	2487476..2487826 (-)	351	WP_003567340.1	hypothetical protein	-
L3C06_RS12050 (L3C06_12050)	-	2488000..2489379 (-)	1380	WP_236360390.1	bacteriocin secretion accessory protein	-
L3C06_RS12055 (L3C06_12055)	comA	2489390..2491582 (-)	2193	WP_236360392.1	peptide cleavage/export ABC transporter	Regulator
L3C06_RS12060 (L3C06_12060)	-	2492049..2492186 (-)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
L3C06_RS12065 (L3C06_12065)	-	2492376..2493674 (+)	1299	WP_236360394.1	GHKL domain-containing protein	-
L3C06_RS12070 (L3C06_12070)	-	2493679..2494485 (+)	807	WP_003567351.1	LytR/AlgR family response regulator transcription factor	-
L3C06_RS12075 (L3C06_12075)	-	2494625..2495545 (-)	921	WP_013245353.1	IS30 family transposase	-
L3C06_RS12080 (L3C06_12080)	-	2495902..2496099 (-)	198	WP_003661762.1	hypothetical protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81320.53 Da
• Isoelectric Point: 7.0227

>NTDB_id=648963 L3C06_RS12055 WP_236360392.1 2489390..2491582(-) (comA) [Lacticaseibacillus paracasei subsp. paracasei strain GR0562]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDSSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPMLARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHTELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=648963 L3C06_RS12055 WP_236360392.1 2489390..2491582(-) (comA) [Lacticaseibacillus paracasei subsp. paracasei strain GR0562]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGAGCTGCTCAGGCACTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATTCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATGCTAGCGCGACAAAAAGGAATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTCGCTTATGTGCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAACGTTTGTCGATTGATGTCATTTTGGGTTACGTCAGACACCTTTATGAATTACCTATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAAATTATTGATGCGCTGGCGAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCTATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACCAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTTACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGTGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCAGGTGGACAAAAGCAG
CGCCTAGCCATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCAATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATACTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.635	98.356	0.577
comA	Streptococcus pneumoniae Rx1	58.078	98.356	0.571
comA	Streptococcus pneumoniae D39	58.078	98.356	0.571
comA	Streptococcus pneumoniae R6	58.078	98.356	0.571
comA	Streptococcus mitis SK321	57.939	98.356	0.57
comA	Streptococcus pneumoniae TIGR4	57.66	98.356	0.567
comA	Streptococcus gordonii str. Challis substr. CH1	56.964	98.356	0.56
comA/nlmT	Streptococcus mutans UA159	54.848	98.904	0.542