Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   SCAZ3_RS01820 Genome accession   NZ_AIDX01000001
Coordinates   395571..397466 (-) Length   631 a.a.
NCBI ID   WP_003044717.1    Uniprot ID   A0AAV3FTM3
Organism   Streptococcus canis FSL Z3-227     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 390571..402466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCAZ3_RS01795 (SCAZ3_08790) - 391321..391680 (-) 360 WP_003044703.1 S1 RNA-binding domain-containing protein -
  SCAZ3_RS01800 (SCAZ3_08795) - 391680..393080 (-) 1401 WP_003044706.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SCAZ3_RS01805 (SCAZ3_08800) - 393117..393758 (-) 642 WP_003044709.1 response regulator transcription factor -
  SCAZ3_RS01810 (SCAZ3_08805) - 393751..394755 (-) 1005 WP_003044712.1 sensor histidine kinase -
  SCAZ3_RS01815 (SCAZ3_08810) liaF 394752..395444 (-) 693 WP_003044714.1 cell wall-active antibiotics response protein LiaF -
  SCAZ3_RS01820 (SCAZ3_08815) pknB 395571..397466 (-) 1896 WP_003044717.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SCAZ3_RS01825 (SCAZ3_08820) - 397463..398203 (-) 741 WP_003044720.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SCAZ3_RS01830 (SCAZ3_08825) rsmB 398241..399563 (-) 1323 WP_003044724.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SCAZ3_RS01835 (SCAZ3_08830) fmt 399553..400488 (-) 936 WP_003044727.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68867.26 Da        Isoelectric Point: 6.9928

>NTDB_id=64760 SCAZ3_RS01820 WP_003044717.1 395571..397466(-) (pknB) [Streptococcus canis FSL Z3-227]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKNGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENHNVP
QALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYNRSRERKVIFDDVESTKPLPKVTPTPMTTPKVAPTPVTSTTESRL
EQTNQMDTLQKPQKKKRNGRFLGTLLKILFSLFIVGVALFTYLVLTKPTSVKVPDVTGVSLKVAKQELQDLGLKVGKVRQ
IESDTVAEGNVVRTDPQAGTAKRKGSSVTVYLSIGNKGFEMENYKGVDYQDAMNSLMETYGIPKSKIKIERIVTNEYPEN
TVISQLPSAGDKFNPNGKSKITLSVAVSDTVIMPMVTEYSYADAVNTLTALGIDASRIKAYAPSSSSATGFIQVNSPSSK
AIVSGQMPYYGTTLSLSEKGEISLYLYPEETHSSSSSSSSESSSSSSSTSDGTGTSSNTELNPSESTGQTP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=64760 SCAZ3_RS01820 WP_003044717.1 395571..397466(-) (pknB) [Streptococcus canis FSL Z3-227]
ATGATTCAGATTGGCAAGTTATTTGCTGGTCGTTATCGTATTCTAAAGTCTATTGGCCGCGGTGGTATGGCGGATGTTTA
TTTGGCAAATGATTTGATCTTGGATAATGAAGACGTTGCAATCAAAGTTTTGCGTACCAATTATCAAACAGATCAGGTGG
CAGTTGCGCGTTTCCAACGGGAAGCGCGGGCCATGGCTGAATTGAATCATCCGAATATTGTTGCCATCCGGGATATAGGT
GAAGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGTGCTGACCTAAAGAAGTACATTCAAGATCATGCACC
GCTATCCAATAACGAAGTGGTTAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCTCACCAAAAAGGAATTGTGC
ATAGGGATTTAAAACCTCAAAACATTCTCTTAACTAAAAATGGTGTGGTTAAGGTGACTGACTTTGGGATTGCTGTTGCC
TTTGCAGAAACGAGTTTGACTCAGACCAACTCGATGTTAGGTAGTGTGCATTATTTGTCTCCGGAGCAGGCTCGTGGTTC
AAAGGCAACTATCCAAAGTGACATTTATGCAATGGGGATTATGCTCTTTGAAATGCTGACAGGGCATATTCCTTATGACG
GTGACAGTGCTGTTACGATTGCCTTGCAACATTTTCAAAAGCCTCTTCCGTCTATTATTGACGAAAATCACAATGTGCCG
CAAGCTTTAGAGAATGTTGTTATCCGAGCAACAGCCAAGAAATTGAGTGATCGTTATGGGTCCACTTTTGAGATGAGCCG
TGACTTGATGACGGCGCTTAGCTACAACCGTAGCCGTGAACGTAAAGTCATTTTTGATGATGTGGAAAGCACTAAGCCGC
TTCCCAAAGTAACCCCAACGCCAATGACAACACCAAAAGTTGCGCCGACTCCAGTTACTTCAACAACTGAAAGTAGATTA
GAGCAAACCAATCAAATGGACACGCTCCAAAAGCCACAAAAAAAGAAAAGAAATGGTCGTTTTTTAGGAACCTTATTGAA
GATTCTTTTTTCTCTCTTTATTGTGGGGGTGGCTCTTTTTACTTACTTGGTATTAACTAAGCCAACTTCTGTGAAAGTTC
CTGATGTAACAGGTGTTAGCTTGAAAGTAGCTAAGCAAGAACTACAAGATCTTGGTCTAAAAGTAGGAAAGGTGCGGCAA
ATTGAAAGCGATACTGTCGCTGAAGGAAATGTTGTCCGAACAGACCCACAAGCAGGAACAGCTAAGCGTAAAGGATCAAG
TGTAACTGTTTATTTGTCAATCGGAAATAAAGGTTTTGAAATGGAAAACTACAAAGGGGTTGATTATCAAGATGCTATGA
ACAGCTTGATGGAAACCTATGGCATTCCAAAATCTAAGATTAAAATTGAACGTATTGTGACCAATGAGTATCCTGAAAAT
ACTGTTATTAGCCAGTTACCAAGTGCAGGAGATAAGTTTAATCCCAATGGTAAATCTAAAATTACCCTTAGCGTAGCCGT
TAGTGACACAGTCATTATGCCAATGGTTACAGAATATAGTTATGCTGATGCGGTTAATACTTTGACAGCACTGGGTATTG
ATGCCTCTAGGATAAAAGCTTATGCGCCAAGTTCAAGTTCAGCAACTGGTTTTATTCAGGTTAATTCCCCTAGTTCAAAA
GCTATTGTTAGTGGACAGATGCCTTATTATGGTACGACATTGAGTCTTTCTGAAAAAGGAGAGATAAGCCTTTATCTTTA
TCCAGAAGAAACACACTCTTCAAGTAGTTCCTCAAGTTCAGAATCAAGTTCAAGTAGTTCCTCAACAAGTGATGGCACTG
GGACAAGTAGCAATACCGAATTAAACCCGTCAGAATCGACTGGACAAACACCTTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-233)

PASTA domain (PASTA)

(371-433)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(511-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.358

92.868

0.607
  stkP/pknB Streptococcus salivarius strain HSISS4

62.034

93.502

0.58
  stkP Streptococcus pneumoniae TIGR4

58.027

81.933

0.475
  stkP Streptococcus pneumoniae D39

57.834

81.933

0.474
  stkP Streptococcus pneumoniae R6

57.834

81.933

0.474
  stkP Streptococcus pneumoniae Rx1

57.418

82.25

0.472

Multiple sequence alignment