Detailed information NTG0646079

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: L1A19_RS09410
• Genome accession: NZ_CP090888
• Coordinates: 1842349..1842810 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PT8465
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1837349..1847810

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A19_RS09380 (L1A19_09380)	-	1837653..1838477 (-)	825	WP_001809383.1	membrane protein insertase YidC	-
L1A19_RS09385 (L1A19_09385)	rnpA	1838452..1838823 (-)	372	WP_000739244.1	ribonuclease P protein component	-
L1A19_RS10575	-	1838840..1838971 (-)	132	WP_000768904.1	hypothetical protein	-
L1A19_RS09390 (L1A19_09390)	-	1838972..1840162 (-)	1191	WP_000167765.1	acetate kinase	-
L1A19_RS09395 (L1A19_09395)	comYH	1840213..1841166 (-)	954	WP_000345099.1	class I SAM-dependent methyltransferase	Machinery gene
L1A19_RS09400 (L1A19_09400)	-	1841227..1841821 (-)	595	Protein_1848	methyltransferase domain-containing protein	-
L1A19_RS09405 (L1A19_09405)	comGG/cglG	1841958..1842371 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
L1A19_RS09410 (L1A19_09410)	comGF/cglF	1842349..1842810 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
L1A19_RS09415 (L1A19_09415)	comGE/cglE	1842773..1843075 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
L1A19_RS09420 (L1A19_09420)	comGD/cglD	1843038..1843442 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
L1A19_RS09425 (L1A19_09425)	comGC/cglC	1843435..1843761 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
L1A19_RS09430 (L1A19_09430)	comGB/cglB	1843763..1844779 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
L1A19_RS09435 (L1A19_09435)	comGA/cglA/cilD	1844727..1845668 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
L1A19_RS09440 (L1A19_09440)	-	1845744..1846109 (-)	366	WP_000286415.1	DUF1033 family protein	-
L1A19_RS09445 (L1A19_09445)	-	1846260..1847318 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=646079 L1A19_RS09410 WP_000250542.1 1842349..1842810(-) (comGF/cglF) [Streptococcus pneumoniae strain PT8465]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=646079 L1A19_RS09410 WP_000250542.1 1842349..1842810(-) (comGF/cglF) [Streptococcus pneumoniae strain PT8465]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909