Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   STRIC_RS09680 Genome accession   NZ_AEUX02000007
Coordinates   385672..386433 (+) Length   253 a.a.
NCBI ID   WP_008090313.1    Uniprot ID   -
Organism   Streptococcus ictaluri 707-05     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 380672..391433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRIC_RS09665 (STRIC_1999) - 381065..382624 (-) 1560 WP_008090433.1 ABC transporter substrate-binding protein/permease -
  STRIC_RS12920 (STRIC_2000) - 382822..383457 (+) 636 WP_008090212.1 DUF2207 domain-containing protein -
  STRIC_RS12925 (STRIC_2001) - 383472..384614 (+) 1143 WP_268741224.1 DUF2207 family protein -
  STRIC_RS09675 (STRIC_2002) - 384700..385539 (+) 840 WP_008090401.1 undecaprenyl-diphosphate phosphatase -
  STRIC_RS09680 (STRIC_2003) mecA 385672..386433 (+) 762 WP_008090313.1 adaptor protein MecA Regulator
  STRIC_RS09685 (STRIC_2004) - 386439..387596 (+) 1158 WP_008090031.1 glycosyltransferase family 4 protein -
  STRIC_RS09690 (STRIC_2005) sufC 387801..388571 (+) 771 WP_008089916.1 Fe-S cluster assembly ATPase SufC -
  STRIC_RS09695 (STRIC_2006) sufD 388622..389884 (+) 1263 WP_008090355.1 Fe-S cluster assembly protein SufD -
  STRIC_RS09700 (STRIC_2007) - 389914..391140 (+) 1227 WP_008090251.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29139.71 Da        Isoelectric Point: 4.1037

>NTDB_id=64591 STRIC_RS09680 WP_008090313.1 385672..386433(+) (mecA) [Streptococcus ictaluri 707-05]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDINLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEEAVEATLSEQSDEVVEKSENTSEPLDYVH
YVLDFASVNDAVYFAKTVDFPVEASELYKSDKSYHMTVLLDVQNQPSYFANVMYARLIEHASPGTRTRAYLQEHGLQLIL
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=64591 STRIC_RS09680 WP_008090313.1 385672..386433(+) (mecA) [Streptococcus ictaluri 707-05]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACCATTAGTATGGATGATTTAGAAGAGAGGGGAATGGAGTT
GAAAGACTTTTTGATTCCTCAGGAAAAGACAGAAGAGTTCTTCTATTCAGTCATGGATGAGCTTGACTTACCAGATAATT
TTAAAGATAGTGGCATGTTGAGTTTTCGAGTGACACCTCGAAAAGATCGTTTGGATGTTTTTGTAACTAAGTCTGAGCTT
AACAAAGACATTAACCTTGAAGATTTGGCTGATTTGGGAGATATTTCTCAGATGACACCAGAAGACTTTTTCAAGAGTTT
GGAACAATCCATGCGTGAAAAAGGCGATGTTAACGCCCATGAAAAACTTGAAAAAATAGAAGAAATGATGGAAGAAGCGG
TAGAAGCAACCCTGTCTGAACAATCTGACGAAGTGGTGGAAAAGTCTGAAAACACTAGTGAACCACTTGATTACGTCCAC
TATGTCTTGGATTTTGCTTCTGTTAATGATGCTGTTTATTTTGCTAAAACGGTTGACTTTCCAGTAGAGGCTTCAGAACT
TTATAAGAGTGATAAGTCTTATCATATGACGGTCTTGCTTGATGTTCAAAACCAACCGTCTTATTTCGCCAATGTTATGT
ATGCACGCTTGATTGAGCATGCTAGTCCAGGTACTAGAACAAGAGCTTACTTACAAGAACATGGATTACAGCTGATTTTG
GATGGCGCTGTTGAGCAATTACAGAAAATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66

98.814

0.652
  mecA Streptococcus thermophilus LMD-9

57.831

98.419

0.569
  mecA Streptococcus thermophilus LMG 18311

57.028

98.419

0.561
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment