Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   STRIC_RS08275 Genome accession   NZ_AEUX02000007
Coordinates   117765..119663 (+) Length   632 a.a.
NCBI ID   WP_008090292.1    Uniprot ID   G5K4H2
Organism   Streptococcus ictaluri 707-05     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 112765..124663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRIC_RS08260 (STRIC_1690) fmt 114744..115679 (+) 936 WP_008090017.1 methionyl-tRNA formyltransferase -
  STRIC_RS08265 (STRIC_1691) rsmB 115669..116991 (+) 1323 WP_040832310.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  STRIC_RS08270 (STRIC_1692) - 117028..117765 (+) 738 WP_008090192.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  STRIC_RS08275 (STRIC_1693) pknB 117765..119663 (+) 1899 WP_008090292.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  STRIC_RS08280 (STRIC_1694) liaF 119803..120495 (+) 693 WP_040832312.1 cell wall-active antibiotics response protein LiaF -
  STRIC_RS08285 (STRIC_1695) - 120492..121493 (+) 1002 WP_008090052.1 sensor histidine kinase -
  STRIC_RS08290 (STRIC_1696) - 121486..122127 (+) 642 WP_008089757.1 response regulator transcription factor -
  STRIC_RS08295 (STRIC_1697) - 122163..123563 (+) 1401 WP_008089870.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  STRIC_RS08300 (STRIC_1698) - 123563..123925 (+) 363 WP_008089664.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 632 a.a.        Molecular weight: 68755.18 Da        Isoelectric Point: 7.0894

>NTDB_id=64578 STRIC_RS08275 WP_008090292.1 117765..119663(+) (pknB) [Streptococcus ictaluri 707-05]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIEENHNVP
QALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYNRSRERKVVFDDVESTKPLPKVTPAPITTPKTSPVTPTTTESRLE
QTNQMDTLQKPQKKKKNGRFLGTLLKILFALFIVGVALFTYLVLTKPTSVKVPNVVGSSLTVAKQELQAKGLKVGAVHQV
ESDTVDEGHVIKTDPQAGTARRQGAKVAIFLSIGNAGFEMENYKGIDYQVAMSSLMETYGVPKSKIKIERIVTNEYNENT
VISQSPSAGEKFNPKGKSKITLSVAVSDTVIMPMVTEYSYAEAVNTLTALGIDASRIKAYIPSSTSSTGFVPLNSPSSKA
IVSGQSPYYGTQLSLSEKGEISLYLYPEESSPSSSSSTHSETSTTSSSSSGENTGSSSNTELTPVDPANGTP

Nucleotide


Download         Length: 1899 bp        

>NTDB_id=64578 STRIC_RS08275 WP_008090292.1 117765..119663(+) (pknB) [Streptococcus ictaluri 707-05]
ATGATACAGATTGGCAAGTTATTTGCTGGTCGTTATCGTATTCTTAAATCTATAGGCCGCGGTGGAATGGCGGATGTTTA
TTTAGCTAATGATTTGATTCTTGATAATGAAGATGTGGCCATAAAGGTTTTACGAACGAATTATCAAACAGATCAGGTAG
CAGTTGCGCGTTTTCAACGTGAAGCACGCGCGATGGCTGAGCTAAACCATCCCAATATAGTTGCCATCAGGGATATAGGT
GAAGAAGACGGTCAGCAGTTTTTAGTGATGGAATATGTGGATGGGTCTGATCTGAAAAAATACATTCAAGATCATGCCCC
ACTCTCTAACAATGAAGTTGTTAGAATCATGGAAGAGGTCTTATCAGCTATGACTTTGGCCCATCAAAAGGGGATTGTTC
ATAGAGATTTAAAACCGCAAAATATTCTTCTCACAAAATCTGGAGTGGTCAAAGTTACTGACTTTGGTATTGCGGTAGCT
TTTGCTGAAACAAGTTTGACTCAAACCAACTCTATGCTAGGAAGTGTTCATTACTTATCACCAGAACAAGCGCGTGGTTC
CAAAGCAACCATTCAAAGCGATATTTATGCTATGGGAATTATGCTATTTGAGATGTTGACAGGTCACATTCCTTATGATG
GGGATAGTGCTGTTACCATTGCTCTACAACATTTCCAAAAGCCGCTTCCATCTATTATTGAGGAAAATCATAATGTCCCT
CAGGCGTTAGAAAATGTCGTTATTAGAGCAACAGCTAAAAAGCTAAGTGATCGTTATGGCTCAACATTTGAAATGAGTAG
AGACTTGATGACAGCATTGAGCTACAATCGTAGTCGCGAGAGAAAAGTTGTTTTTGACGACGTTGAAAGCACTAAACCGT
TACCAAAAGTAACGCCAGCTCCAATTACGACACCAAAAACAAGTCCTGTGACACCGACCACTACTGAAAGCCGATTAGAG
CAAACGAATCAAATGGATACCTTACAGAAACCCCAGAAGAAGAAAAAAAATGGTCGTTTCTTAGGAACTCTATTGAAAAT
ATTATTTGCCCTCTTTATTGTAGGTGTTGCTTTGTTTACTTACCTTGTCTTGACCAAACCAACCTCTGTTAAAGTGCCTA
ATGTAGTTGGTTCTAGCTTAACTGTGGCTAAACAAGAATTGCAAGCTAAAGGTTTAAAAGTTGGTGCAGTTCATCAAGTA
GAGAGTGATACGGTTGATGAAGGGCATGTCATTAAGACAGATCCTCAAGCTGGGACAGCAAGACGTCAAGGTGCTAAAGT
AGCTATTTTCCTTTCTATTGGCAATGCTGGTTTTGAAATGGAAAATTATAAAGGAATTGATTACCAAGTTGCCATGAGTA
GCTTAATGGAAACCTATGGTGTTCCTAAGTCAAAAATTAAAATTGAGCGTATTGTAACGAATGAGTACAATGAAAACACA
GTGATTAGTCAATCACCAAGTGCAGGAGAAAAATTCAATCCAAAAGGTAAATCGAAGATTACCCTAAGTGTGGCAGTTAG
TGATACTGTTATTATGCCTATGGTGACAGAGTATAGTTATGCAGAAGCTGTTAATACGCTAACAGCACTAGGTATTGATG
CTTCACGTATTAAAGCTTATATACCAAGCTCCACTTCTTCAACAGGATTTGTCCCCCTTAATTCACCAAGTTCAAAAGCC
ATTGTTAGTGGTCAAAGTCCCTATTATGGGACACAACTGAGCTTATCAGAAAAAGGGGAAATTAGTCTTTACCTTTATCC
TGAAGAAAGCAGCCCATCAAGTAGTAGTTCCACTCATTCTGAAACCTCTACCACAAGTAGTAGTTCTTCAGGTGAAAACA
CAGGAAGTTCAAGTAACACTGAATTAACACCAGTTGATCCAGCAAATGGAACACCTTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(510-586)

PASTA domain (PASTA)

(370-432)

PASTA domain (PASTA)

(439-504)

Protein kinase domain (Pkinase)

(12-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K4H2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.128

92.563

0.603
  stkP/pknB Streptococcus salivarius strain HSISS4

65.771

88.291

0.581
  stkP Streptococcus pneumoniae TIGR4

58.56

81.329

0.476
  stkP Streptococcus pneumoniae D39

58.366

81.329

0.475
  stkP Streptococcus pneumoniae R6

58.366

81.329

0.475
  stkP Streptococcus pneumoniae Rx1

58.171

81.329

0.473

Multiple sequence alignment