Detailed information NTG0645695

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: L1A14_RS08065
• Genome accession: NZ_CP090883
• Coordinates: 1579935..1581914 (-)
• Length: 659 a.a.
• NCBI ID: WP_000614540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain LE4448
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Genomic Context

Location: 1574935..1586914

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A14_RS08035 (L1A14_08035)	-	1575033..1576307 (-)	1275	WP_000704388.1	hydroxymethylglutaryl-CoA reductase, degradative	-
L1A14_RS08040 (L1A14_08040)	-	1576307..1577479 (-)	1173	WP_000151957.1	hydroxymethylglutaryl-CoA synthase	-
L1A14_RS08045 (L1A14_08045)	-	1577610..1577858 (-)	249	WP_001813143.1	hypothetical protein	-
L1A14_RS08050 (L1A14_08050)	-	1577926..1578549 (-)	624	Protein_1599	IS5 family transposase	-
L1A14_RS08055 (L1A14_08055)	-	1578611..1579060 (-)	450	WP_000176924.1	threonine/serine exporter family protein	-
L1A14_RS08060 (L1A14_08060)	-	1579062..1579820 (-)	759	WP_000392880.1	threonine/serine exporter ThrE family protein	-
L1A14_RS08065 (L1A14_08065)	stkP	1579935..1581914 (-)	1980	WP_000614540.1	serine/threonine-protein kinase StkP	Regulator
L1A14_RS08070 (L1A14_08070)	-	1581911..1582651 (-)	741	WP_000406248.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
L1A14_RS08075 (L1A14_08075)	rsmB	1582666..1583979 (-)	1314	WP_001808992.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
L1A14_RS08080 (L1A14_08080)	fmt	1583972..1584907 (-)	936	WP_000163693.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 659 a.a.
• Molecular weight: 72316.86 Da
• Isoelectric Point: 9.0945

>NTDB_id=645695 L1A14_RS08065 WP_000614540.1 1579935..1581914(-) (stkP) [Streptococcus pneumoniae strain LE4448]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide

• Length: 1980 bp

>NTDB_id=645695 L1A14_RS08065 WP_000614540.1 1579935..1581914(-) (stkP) [Streptococcus pneumoniae strain LE4448]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCCGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
TAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGCTCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATCTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCTTCTGATGTTATCGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCCAATGAGAGTGAGGCTGGAACGGTC
CTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGTAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTA
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-227)

• PASTA domain (PASTA) (440-505)

• PASTA domain (PASTA) (582-651)

• PASTA domain (PASTA) (513-577)

• PASTA domain (PASTA) (371-432)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	99.848	100	0.998
stkP	Streptococcus pneumoniae D39	99.697	100	0.997
stkP	Streptococcus pneumoniae R6	99.697	100	0.997
stkP	Streptococcus pneumoniae Rx1	99.545	100	0.995
pknB	Streptococcus mutans UA159	52.65	88.771	0.467
stkP/pknB	Streptococcus salivarius strain HSISS4	51.807	88.164	0.457