Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SPB_RS07805 Genome accession   NZ_AEUT02000001
Coordinates   1556436..1557191 (-) Length   251 a.a.
NCBI ID   WP_003104886.1    Uniprot ID   A0A854WQ82
Organism   Streptococcus parauberis NCFD 2020     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1551436..1562191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPB_RS07785 (SPB_1604) - 1551775..1553001 (-) 1227 WP_003105991.1 cysteine desulfurase -
  SPB_RS07790 (SPB_1605) sufD 1553026..1554288 (-) 1263 WP_003102572.1 Fe-S cluster assembly protein SufD -
  SPB_RS07795 (SPB_1606) sufC 1554377..1555147 (-) 771 WP_003103864.1 Fe-S cluster assembly ATPase SufC -
  SPB_RS07800 (SPB_1607) - 1555272..1556429 (-) 1158 WP_003104405.1 glycosyltransferase family 4 protein -
  SPB_RS07805 (SPB_1608) mecA 1556436..1557191 (-) 756 WP_003104886.1 adaptor protein MecA Regulator
  SPB_RS07810 (SPB_1609) - 1557295..1558134 (-) 840 WP_003102685.1 undecaprenyl-diphosphate phosphatase -
  SPB_RS07815 (SPB_1610) - 1558209..1560113 (-) 1905 WP_003103368.1 DUF2207 domain-containing protein -
  SPB_RS07820 (SPB_1611) - 1560319..1561887 (+) 1569 WP_003104342.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29182.86 Da        Isoelectric Point: 4.1299

>NTDB_id=64562 SPB_RS07805 WP_003104886.1 1556436..1557191(-) (mecA) [Streptococcus parauberis NCFD 2020]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKDINFEDLAELGDISQMTPEDFFKTIEKNMMEKGDVDAHQKLEKIEEMLEDASAQAQEQAKVAEQEEYEAEVLDYVHFV
LNFASIEDAINFSKTIDFPIEASELYKESKSYHMTILLDVQNQPSYYANVSYARLIEHANPGIRTRAYLQEHGIQLIEDN
AVEELKKIEMV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=64562 SPB_RS07805 WP_003104886.1 1556436..1557191(-) (mecA) [Streptococcus parauberis NCFD 2020]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATAACGATCAGCATGGATGATTTAGAAGAAAGAGGTATGGAATT
AAAAGATTTCTTGATTCCACAAGAAAAGACCGAAGAATTTTTCTATTCAGTTATGGATGAACTTGATTTACCAGAAAACT
TTAAAGATAGTGGTATGCTTAGTTTCAGAGTGACACCTCGAAAAGATCGATTAGATGTCTTTGTTACAAAATCAGAATTA
AGTAAAGACATCAATTTTGAAGATTTAGCTGAACTAGGTGATATTTCACAAATGACGCCTGAAGATTTTTTCAAAACGAT
TGAAAAAAACATGATGGAAAAAGGTGATGTCGATGCTCACCAAAAATTAGAGAAAATTGAAGAAATGCTTGAGGATGCTT
CTGCTCAGGCGCAGGAGCAAGCAAAAGTTGCTGAACAAGAAGAGTATGAAGCAGAAGTTCTTGATTATGTTCACTTCGTA
TTGAATTTTGCTTCTATTGAAGATGCAATTAATTTTTCAAAAACAATTGATTTCCCAATTGAAGCATCTGAGTTATATAA
GGAAAGCAAAAGTTATCACATGACTATTTTATTAGATGTTCAAAATCAACCTTCATATTATGCAAATGTTAGCTATGCAC
GTTTAATTGAACATGCTAATCCTGGGATTAGGACCAGAGCTTATTTACAGGAGCATGGCATTCAATTAATTGAAGATAAT
GCTGTTGAAGAATTGAAAAAAATTGAGATGGTGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A854WQ82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.113

98.805

0.633
  mecA Streptococcus thermophilus LMD-9

56.855

98.805

0.562
  mecA Streptococcus thermophilus LMG 18311

56.048

98.805

0.554
  mecA Streptococcus pneumoniae Rx1

47.431

100

0.478
  mecA Streptococcus pneumoniae D39

47.431

100

0.478
  mecA Streptococcus pneumoniae R6

47.431

100

0.478
  mecA Streptococcus pneumoniae TIGR4

47.431

100

0.478

Multiple sequence alignment