Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STRSA0001_RS01190 Genome accession   NZ_ACLO01000018
Coordinates   63037..63726 (-) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius SK126     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 58037..68726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRSA0001_RS01170 (STRSA0001_1768) dnaI 58832..59734 (-) 903 WP_002883792.1 primosomal protein DnaI -
  STRSA0001_RS01175 (STRSA0001_1769) - 59738..60913 (-) 1176 WP_002883810.1 DnaD domain protein -
  STRSA0001_RS01180 (STRSA0001_1770) nrdR 60910..61389 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  STRSA0001_RS01185 (STRSA0001_1771) covS 61511..63040 (-) 1530 WP_002883784.1 HAMP domain-containing sensor histidine kinase Regulator
  STRSA0001_RS01190 (STRSA0001_1772) covR 63037..63726 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  STRSA0001_RS01195 (STRSA0001_1773) - 63882..64418 (-) 537 WP_002883813.1 DUF177 domain-containing protein -
  STRSA0001_RS01200 (STRSA0001_1774) rsmG 64717..65430 (+) 714 WP_002883809.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STRSA0001_RS01205 (STRSA0001_1775) - 65499..66863 (+) 1365 WP_002883736.1 TrkH family potassium uptake protein -
  STRSA0001_RS01210 (STRSA0001_1776) - 66903..67574 (+) 672 WP_002883759.1 potassium channel family protein -
  STRSA0001_RS01215 (STRSA0001_1777) - 67663..68493 (-) 831 WP_002883773.1 energy-coupling factor transporter transmembrane component T family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=64493 STRSA0001_RS01190 WP_002883757.1 63037..63726(-) (covR) [Streptococcus salivarius SK126]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=64493 STRSA0001_RS01190 WP_002883757.1 63037..63726(-) (covR) [Streptococcus salivarius SK126]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTAGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment