Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   STRSA0001_RS01185 Genome accession   NZ_ACLO01000018
Coordinates   61511..63040 (-) Length   509 a.a.
NCBI ID   WP_002883784.1    Uniprot ID   A0A1V0GG48
Organism   Streptococcus salivarius SK126     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 56511..68040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRSA0001_RS01160 (STRSA0001_1766) - 56723..57352 (-) 630 WP_002883768.1 hypothetical protein -
  STRSA0001_RS01165 (STRSA0001_1767) der 57416..58726 (-) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  STRSA0001_RS01170 (STRSA0001_1768) dnaI 58832..59734 (-) 903 WP_002883792.1 primosomal protein DnaI -
  STRSA0001_RS01175 (STRSA0001_1769) - 59738..60913 (-) 1176 WP_002883810.1 DnaD domain protein -
  STRSA0001_RS01180 (STRSA0001_1770) nrdR 60910..61389 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  STRSA0001_RS01185 (STRSA0001_1771) covS 61511..63040 (-) 1530 WP_002883784.1 HAMP domain-containing sensor histidine kinase Regulator
  STRSA0001_RS01190 (STRSA0001_1772) covR 63037..63726 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  STRSA0001_RS01195 (STRSA0001_1773) - 63882..64418 (-) 537 WP_002883813.1 DUF177 domain-containing protein -
  STRSA0001_RS01200 (STRSA0001_1774) rsmG 64717..65430 (+) 714 WP_002883809.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STRSA0001_RS01205 (STRSA0001_1775) - 65499..66863 (+) 1365 WP_002883736.1 TrkH family potassium uptake protein -
  STRSA0001_RS01210 (STRSA0001_1776) - 66903..67574 (+) 672 WP_002883759.1 potassium channel family protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58071.44 Da        Isoelectric Point: 5.1853

>NTDB_id=64492 STRSA0001_RS01185 WP_002883784.1 61511..63040(-) (covS) [Streptococcus salivarius SK126]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=64492 STRSA0001_RS01185 WP_002883784.1 61511..63040(-) (covS) [Streptococcus salivarius SK126]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCCAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCGAAAAATATCTATGCATCGATCATTAATGGTGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
AGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGACTCGCCTCCAGGTATGTCCGAGGTAAACAAACTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGTTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATTTTCCATGATTTGGAATTCTA
TTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCGGTTATTAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTTGAGAGTTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

100

100

1

Multiple sequence alignment