Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   LOD78_RS00335 Genome accession   NZ_CP090522
Coordinates   57311..59464 (+) Length   717 a.a.
NCBI ID   WP_024403979.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SS17     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 52311..64464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOD78_RS00315 (LOD78_00310) - 52502..53770 (+) 1269 WP_174846490.1 MerR family transcriptional regulator -
  LOD78_RS00320 (LOD78_00315) - 54105..55269 (+) 1165 Protein_43 IS110 family transposase -
  LOD78_RS00325 (LOD78_00320) - 56339..56491 (+) 153 WP_079269043.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  LOD78_RS00330 (LOD78_00325) - 56678..56839 (+) 162 WP_172006749.1 hypothetical protein -
  LOD78_RS00335 (LOD78_00330) comA 57311..59464 (+) 2154 WP_024403979.1 peptide cleavage/export ABC transporter ComA Regulator
  LOD78_RS00340 (LOD78_00335) comB 59476..60828 (+) 1353 WP_174846492.1 bacteriocin secretion accessory protein Regulator
  LOD78_RS00345 (LOD78_00340) - 61216..61395 (+) 180 WP_024392853.1 hypothetical protein -
  LOD78_RS00350 (LOD78_00345) - 61396..61596 (+) 201 WP_239604410.1 hypothetical protein -
  LOD78_RS00355 (LOD78_00350) - 61613..61804 (+) 192 WP_024392851.1 hypothetical protein -
  LOD78_RS00360 (LOD78_00355) - 62165..63034 (-) 870 WP_130555553.1 cysteine ABC transporter substrate-binding protein -
  LOD78_RS00365 (LOD78_00360) - 63047..63793 (-) 747 WP_171989021.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81106.38 Da        Isoelectric Point: 7.0405

>NTDB_id=643156 LOD78_RS00335 WP_024403979.1 57311..59464(+) (comA) [Streptococcus parasuis strain SS17]
MKFGKRHYRAQVDTRDCGVAALAMILEYYRSHHSLASLREMAKTTMEGTTAFGLVKVAEELGFETRAIKADMSLFSMREA
VYPFIAHVVKDGTLLHYYVVIGADKKYIYIADPDPSVKLTKLSHEQFEKEWTGVSLFMAPKPEYQPHKEKSHGLLSFIPL
LTKQKGLITNIVLATLLVTFINIVGSYYLQSIIDTYVPNQMKTTLGVISVGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIVVVVSVVLFSQNVYLFFISLLALPIYTL
IIFAFMKPFEKMNQEVMESNAILSSSIIEDINGIETIKSLTSEKQRYQKIDREFVDYLQKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGACLVMDQKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTAQVANTRLNEVYLVESEFAEKKSVTDLSLL
SGDIECNKVHYKYGYGRDVLTDINLKIKRGEKVSFVGVSGSGKTTLAKMMVDFYDPYKGEIRLNNVNINQIDKQTLRQHI
NYLPQQPYVFNGTILENLLLGAKEGTSQEDILWAVEMACIREDIEKMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLSLDKTLIFIAHRLTIAERTEHIVVLDKGRIVEQGSHKELLDKQGFYEYLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=643156 LOD78_RS00335 WP_024403979.1 57311..59464(+) (comA) [Streptococcus parasuis strain SS17]
ATGAAATTTGGAAAACGTCATTATAGAGCACAAGTAGATACACGAGACTGTGGTGTAGCAGCGCTTGCTATGATCTTGGA
ATATTATCGTTCTCATCATTCTTTAGCAAGTTTGCGAGAAATGGCAAAGACAACTATGGAAGGCACGACAGCATTTGGTT
TAGTAAAGGTTGCTGAAGAGCTAGGGTTTGAGACGCGTGCGATTAAGGCAGATATGTCTTTGTTTTCGATGAGGGAAGCG
GTCTATCCTTTCATTGCCCATGTGGTAAAAGATGGCACGTTACTACATTATTATGTTGTCATTGGGGCAGATAAGAAATA
TATCTATATTGCAGACCCGGATCCATCAGTGAAATTAACAAAGTTATCCCATGAACAATTTGAAAAGGAGTGGACAGGAG
TTTCGCTATTCATGGCTCCCAAACCGGAATATCAACCTCATAAAGAGAAGAGTCATGGGTTACTTTCTTTCATTCCATTG
TTGACTAAACAAAAGGGATTGATTACAAATATTGTTCTCGCAACGCTCTTGGTTACTTTCATCAACATTGTGGGCTCCTA
TTATTTACAATCCATTATTGACACTTATGTTCCAAATCAGATGAAAACAACATTAGGTGTCATTTCAGTCGGTTTGGTGG
TTGTTTATGCCCTGCAACAATTGTTATCTTATGCCCAAGAATATTTATTAATCATTCTTGGGCAACGACTCTCTATTGAT
GTGATTTTGTCTTATATTAGACATGTTTTTCATCTACCAATGTCATTTTTTGCTACTCGGCGAACTGGGGAAATTGTTTC
ACGATTTACAGATGCCAATTCTATTATTGATGCTTTAGCTAGTACCATTCTATCAATATTTTTGGATGTATCTATTGTTG
TGGTTGTTTCGGTAGTGCTGTTTAGTCAGAATGTCTATCTTTTCTTTATTTCCTTATTGGCATTGCCAATCTATACTCTA
ATCATTTTTGCGTTTATGAAACCATTTGAAAAGATGAATCAAGAAGTGATGGAAAGTAATGCAATTCTTTCTTCGTCTAT
TATTGAAGATATTAATGGTATTGAAACCATAAAATCATTGACAAGTGAGAAACAACGTTATCAGAAAATTGATAGAGAAT
TTGTAGATTATTTACAAAAATCATTTGCATACAACAAGGCCGAAGGGCAGCAAAAAGTGTTAAAGCGCTTGGCCCAACTC
GTATTAAATGTAGCAATTCTTTGGTTAGGAGCCTGTCTTGTTATGGATCAGAAAATGACTTTGGGGCAGCTAATCACCTT
CAATACGTTATTGGTCTATTTCACGAATCCATTGGAAAATATAATCAATTTACAAACAAAACTACAGACAGCTCAAGTTG
CCAATACCCGCTTGAACGAGGTCTATTTGGTTGAATCGGAATTTGCTGAAAAGAAATCCGTGACGGACCTTTCGTTACTT
TCGGGGGATATTGAATGCAACAAAGTGCATTATAAATATGGCTATGGTAGGGATGTTTTGACAGATATTAATTTGAAAAT
TAAACGAGGGGAAAAGGTCTCCTTTGTTGGAGTTTCTGGTTCTGGGAAGACGACGTTGGCTAAAATGATGGTGGATTTTT
ATGACCCTTACAAGGGTGAGATTCGATTAAATAATGTCAACATTAATCAAATCGATAAGCAAACACTTCGTCAGCATATT
AATTATCTTCCACAGCAACCCTATGTTTTTAATGGGACAATTCTCGAAAATCTATTGCTAGGTGCAAAAGAGGGAACAAG
TCAAGAAGATATCTTGTGGGCTGTTGAAATGGCATGTATTAGAGAAGATATTGAAAAAATGCCACTGAATTACCAAACGG
AATTGACTTCTGATGGAGCTGGAATTTCCGGTGGACAACGGCAGCGAATTGCCTTGGCGCGTGCCCTTCTTACGGATGCC
CCTATTATGATTTTGGATGAGGCAACCAGTAGTCTGGATATTTTGACAGAGAAGCGTATTGTGGACAACCTATTGTCATT
GGACAAAACTCTAATTTTTATTGCACATCGGTTAACCATTGCAGAGCGTACTGAACATATTGTTGTGCTAGATAAGGGAA
GAATTGTAGAACAAGGGAGTCATAAGGAATTGTTAGACAAGCAAGGGTTCTATGAATATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae Rx1

79.777

100

0.798
  comA Streptococcus pneumoniae D39

79.777

100

0.798
  comA Streptococcus pneumoniae R6

79.777

100

0.798
  comA Streptococcus mitis NCTC 12261

79.637

100

0.796
  comA Streptococcus pneumoniae TIGR4

79.498

100

0.795
  comA Streptococcus mitis SK321

79.498

100

0.795
  comA Streptococcus gordonii str. Challis substr. CH1

77.406

100

0.774
  comA/nlmT Streptococcus mutans UA159

63.598

100

0.636