NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	OGM43_RS11425	Genome accession	NZ_CP107147
Coordinates	2317466..2318590 (-)	Length	374 a.a.
NCBI ID	WP_000228517.1	Uniprot ID	A0A0H3EME5
Organism	Escherichia coli strain R14
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2312466..2323590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OGM43_RS11395 (OGM43_11370)	yrdA	2314266..2314820 (+)	555	WP_000005712.1	gamma carbonic anhydrase family protein	-
OGM43_RS11400 (OGM43_11375)	yrdB	2314796..2315053 (-)	258	WP_001070565.1	DUF1488 domain-containing protein	-
OGM43_RS11405 (OGM43_11380)	aroE	2315050..2315868 (-)	819	WP_000451255.1	shikimate dehydrogenase	-
OGM43_RS11410 (OGM43_11385)	tsaC	2315873..2316445 (-)	573	WP_001296460.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
OGM43_RS11415 (OGM43_11390)	yrdD	2316450..2316992 (-)	543	WP_001296461.1	type I DNA topoisomerase	-
OGM43_RS11420 (OGM43_11395)	smg	2317021..2317494 (-)	474	WP_000460673.1	DUF494 family protein Smg	-
OGM43_RS11425 (OGM43_11400)	dprA	2317466..2318590 (-)	1125	WP_000228517.1	DNA-protecting protein DprA	Machinery gene
OGM43_RS11430 (OGM43_11405)	def	2318720..2319229 (+)	510	WP_000114984.1	peptide deformylase	-
OGM43_RS11435 (OGM43_11410)	fmt	2319244..2320191 (+)	948	WP_000004421.1	methionyl-tRNA formyltransferase	-
OGM43_RS11440 (OGM43_11415)	rsmB	2320243..2321532 (+)	1290	WP_000744765.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
OGM43_RS11445 (OGM43_11420)	trkA	2321554..2322930 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
OGM43_RS11450 (OGM43_11425)	mscL	2323060..2323473 (+)	414	WP_000022450.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40910.86 Da Isoelectric Point: 6.0395

                                >NTDB_id=641412 OGM43_RS11425 WP_000228517.1 2317466..2318590(-) (dprA) [Escherichia coli strain R14]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=641412 OGM43_RS11425 WP_000228517.1 2317466..2318590(-) (dprA) [Escherichia coli strain R14]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT

TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAGGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0H3EME5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.78	98.663	0.481
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.355	82.888	0.409
dprA	Vibrio cholerae strain A1552	49.355	82.888	0.409
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	44.242	88.235	0.39

Detailed information NTG0641412