Detailed information NTG0640426

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: PALA20_RS26500
• Genome accession: NZ_CP107064
• Coordinates: 5686777..5687448 (-)
• Length: 223 a.a.
• NCBI ID: WP_003090494.1
• Uniprot ID: A0A0H2ZC88
• Organism: Pseudomonas aeruginosa strain PALA20
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 5681777..5692448

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PALA20_RS33120	-	5683114..5684181 (+)	1068	Protein_5236	HAMP domain-containing protein	-
PALA20_RS33125	-	5684503..5685039 (+)	537	Protein_5237	methyl-accepting chemotaxis protein	-
PALA20_RS26490 (PALA20_05245)	-	5685044..5685352 (-)	309	WP_003090492.1	hypothetical protein	-
PALA20_RS26495 (PALA20_05246)	carS	5685443..5686780 (-)	1338	WP_003090493.1	two-component system sensor histidine kinase CarS	-
PALA20_RS26500 (PALA20_05247)	ciaR	5686777..5687448 (-)	672	WP_003090494.1	two-component system response regulator CarR	Regulator
PALA20_RS26505 (PALA20_05248)	-	5687448..5687762 (-)	315	WP_003131079.1	PepSY domain-containing protein	-
PALA20_RS26510 (PALA20_05249)	-	5687762..5688070 (-)	309	WP_003090497.1	PepSY domain-containing protein	-
PALA20_RS26515 (PALA20_05250)	-	5688285..5689367 (+)	1083	WP_003090498.1	hypothetical protein	-
PALA20_RS26520 (PALA20_05251)	-	5689394..5690287 (+)	894	WP_003090499.1	hypothetical protein	-
PALA20_RS26525 (PALA20_05252)	-	5690271..5690537 (+)	267	WP_003090500.1	DUF5329 domain-containing protein	-
PALA20_RS26530 (PALA20_05253)	-	5690538..5691731 (-)	1194	WP_003090501.1	NnrS family protein	-
PALA20_RS26535 (PALA20_05254)	ppyR	5691718..5691975 (-)	258	WP_003090502.1	psl/pyoverdine operon transcriptional regulator PpyR	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 24729.20 Da
• Isoelectric Point: 5.8445

>NTDB_id=640426 PALA20_RS26500 WP_003090494.1 5686777..5687448(-) (ciaR) [Pseudomonas aeruginosa strain PALA20]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide

• Length: 672 bp

>NTDB_id=640426 PALA20_RS26500 WP_003090494.1 5686777..5687448(-) (ciaR) [Pseudomonas aeruginosa strain PALA20]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAGCCCTACGACCTGATCATCCTCGACCTCGGCC
TGCCCGGGCGCCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGGCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGGTTCCTGGGCCGAACGCATCGATGGCCTCAAGGCCGGTGCCGACGACTACCTGACCAAGCCGTTCCATCCGGAAGA
GTTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC
GCCTGGACGAGCAGCGCCAGTGCGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAATGTCATCGAGGTCCACGTCAACCACTTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-216)

3D structure

• AlphaFold DB: A0A0H2ZC88

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	37.727	98.655	0.372
ciaR	Streptococcus pneumoniae Rx1	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae D39	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae R6	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae TIGR4	37.273	98.655	0.368
micA	Streptococcus pneumoniae Cp1015	35.683	100	0.363
vicR	Streptococcus mutans UA159	35.526	100	0.363