Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LV497_RS06435 Genome accession   NZ_CP090007
Coordinates   1402866..1403555 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain SALI-10     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1397866..1408555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS06410 (LV497_06410) - 1398098..1398928 (+) 831 WP_073687403.1 energy-coupling factor transporter transmembrane protein EcfT -
  LV497_RS06415 (LV497_06415) - 1399018..1399689 (-) 672 WP_073686620.1 TrkA family potassium uptake protein -
  LV497_RS06420 (LV497_06420) - 1399729..1401093 (-) 1365 WP_080977677.1 TrkH family potassium uptake protein -
  LV497_RS06425 (LV497_06425) rsmG 1401162..1401875 (-) 714 WP_049529060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  LV497_RS06430 (LV497_06430) - 1402174..1402710 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  LV497_RS06435 (LV497_06435) covR 1402866..1403555 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  LV497_RS06440 (LV497_06440) covS 1403552..1405081 (+) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  LV497_RS06445 (LV497_06445) nrdR 1405203..1405682 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  LV497_RS06450 (LV497_06450) - 1405679..1406854 (+) 1176 WP_155213032.1 DnaD domain protein -
  LV497_RS06455 (LV497_06455) dnaI 1406858..1407760 (+) 903 WP_002883792.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=640137 LV497_RS06435 WP_002883757.1 1402866..1403555(+) (covR) [Streptococcus salivarius strain SALI-10]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=640137 LV497_RS06435 WP_002883757.1 1402866..1403555(+) (covR) [Streptococcus salivarius strain SALI-10]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTTGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGTGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCCAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445