Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LV497_RS06440 Genome accession   NZ_CP090007
Coordinates   1403552..1405081 (+) Length   509 a.a.
NCBI ID   WP_014633896.1    Uniprot ID   A0AB33ZGE8
Organism   Streptococcus salivarius strain SALI-10     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1398552..1410081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS06415 (LV497_06415) - 1399018..1399689 (-) 672 WP_073686620.1 TrkA family potassium uptake protein -
  LV497_RS06420 (LV497_06420) - 1399729..1401093 (-) 1365 WP_080977677.1 TrkH family potassium uptake protein -
  LV497_RS06425 (LV497_06425) rsmG 1401162..1401875 (-) 714 WP_049529060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  LV497_RS06430 (LV497_06430) - 1402174..1402710 (+) 537 WP_002883813.1 DUF177 domain-containing protein -
  LV497_RS06435 (LV497_06435) covR 1402866..1403555 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  LV497_RS06440 (LV497_06440) covS 1403552..1405081 (+) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  LV497_RS06445 (LV497_06445) nrdR 1405203..1405682 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  LV497_RS06450 (LV497_06450) - 1405679..1406854 (+) 1176 WP_155213032.1 DnaD domain protein -
  LV497_RS06455 (LV497_06455) dnaI 1406858..1407760 (+) 903 WP_002883792.1 primosomal protein DnaI -
  LV497_RS06460 (LV497_06460) der 1407865..1409175 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  LV497_RS06465 (LV497_06465) - 1409239..1409868 (+) 630 WP_070575915.1 ribonuclease P -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58085.46 Da        Isoelectric Point: 5.1853

>NTDB_id=640138 LV497_RS06440 WP_014633896.1 1403552..1405081(+) (covS) [Streptococcus salivarius strain SALI-10]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVIFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=640138 LV497_RS06440 WP_014633896.1 1403552..1405081(+) (covS) [Streptococcus salivarius strain SALI-10]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTATTTTCTCAGCCAATACGCTACTTTTACAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATAGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCTGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGCGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAGGTAAACAAATTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGCTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATTTTCCATGATTTGGAATTCTA
CTATGCCCTTAAGGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTAATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATTAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGACATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAATTTCCGTGTCTTGCATGAAGACTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAACC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.804

100

0.998