Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   LV497_RS02110 Genome accession   NZ_CP090007
Coordinates   559787..561658 (-) Length   623 a.a.
NCBI ID   WP_022496268.1    Uniprot ID   -
Organism   Streptococcus salivarius strain SALI-10     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 554787..566658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS02075 (LV497_02075) rimM 555164..555682 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  LV497_RS02090 (LV497_02090) - 556378..557022 (-) 645 WP_022496266.1 response regulator transcription factor -
  LV497_RS02095 (LV497_02095) - 557012..558022 (-) 1011 WP_013990239.1 sensor histidine kinase -
  LV497_RS02100 (LV497_02100) liaF 558019..558717 (-) 699 WP_022496267.1 cell wall-active antibiotics response protein LiaF -
  LV497_RS02105 (LV497_02105) - 558881..559639 (-) 759 WP_002884314.1 potassium channel family protein -
  LV497_RS02110 (LV497_02110) stkP/pknB 559787..561658 (-) 1872 WP_022496268.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  LV497_RS02115 (LV497_02115) - 561658..562395 (-) 738 WP_037604753.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  LV497_RS02120 (LV497_02120) rsmB 562439..563761 (-) 1323 WP_002884194.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  LV497_RS02125 (LV497_02125) fmt 563751..564686 (-) 936 WP_002884812.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67756.43 Da        Isoelectric Point: 6.5787

>NTDB_id=640096 LV497_RS02110 WP_022496268.1 559787..561658(-) (stkP/pknB) [Streptococcus salivarius strain SALI-10]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEVE
DDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGGKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGEI
LSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSSTEVL
YQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=640096 LV497_RS02110 WP_022496268.1 559787..561658(-) (stkP/pknB) [Streptococcus salivarius strain SALI-10]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTATCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTAGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTTACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGGTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTAACAGGTCATATTCCTTACGATG
GCGATAGTGCGGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCAAAGGTTGATCCAGTTCCATCAGCAAGCCTTGAGAAAAAGGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCGAGGAAGAAAACGACACCAGCTAAGAAGAAAAAGAAGAATTTCTTCTCAACTTTACTCAAGGTTTT
CCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTAATG
TGGTCGGCCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTTAAAGAAGTGGAA
GATGACTCTGTTGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACTACACGAAAAGAAGGATCAAGCATTGA
TGTCTATGTTTCTTCTGGTGGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAATTATAAGGATGCCATTGAGGACT
TAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAAATC
CTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAACTCC
TAAGACCGTCACCATGCCTGATGTGACTGGTTTAACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCTCAA
GTAGTAGCATCGAGTACCACGACTATAATACTGGTGCCAAGTTAGATAAGGATAAGGTTCCTAGCAGTACAGAGGTCCTT
TATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCAGTTGCAACAGCAAGTTCAAGTCT
ACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAACCT
CGACAGAGGCTACTCACACAGAGCTACAGTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(440-504)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.558

100

0.987
  pknB Streptococcus mutans UA159

67.159

86.998

0.584
  stkP Streptococcus pneumoniae TIGR4

52.069

93.098

0.485
  stkP Streptococcus pneumoniae D39

51.897

93.098

0.483
  stkP Streptococcus pneumoniae R6

51.897

93.098

0.483
  stkP Streptococcus pneumoniae Rx1

51.724

93.098

0.482