Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   LXA46_RS11010 Genome accession   NZ_CP089948
Coordinates   511108..511695 (-) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae TIGR4     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 506108..516695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS02455 (LXA46_02450) - 506570..507910 (+) 1341 WP_001017646.1 sensor histidine kinase -
  LXA46_RS02460 (LXA46_02455) blpC 507981..508109 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  LXA46_RS02465 (LXA46_02460) - 508166..509527 (-) 1362 WP_001069075.1 bacteriocin secretion accessory protein -
  LXA46_RS11000 comA/nlmT 509538..510185 (-) 648 WP_078064020.1 ATP-binding cassette domain-containing protein Regulator
  LXA46_RS11005 comA/nlmT 510201..511214 (-) 1014 WP_307772067.1 ABC transporter transmembrane domain-containing protein Regulator
  LXA46_RS11010 comA/nlmT 511108..511695 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  LXA46_RS02475 (LXA46_02470) blpI 511977..512174 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  LXA46_RS02480 (LXA46_02475) blpJ 512641..512910 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  LXA46_RS02485 (LXA46_02480) blpU 512979..513209 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  LXA46_RS02490 (LXA46_02485) - 513212..513331 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  LXA46_RS02495 (LXA46_02490) - 513628..513792 (+) 165 WP_000727118.1 hypothetical protein -
  LXA46_RS02500 (LXA46_02495) - 513789..514193 (+) 405 WP_000846943.1 hypothetical protein -
  LXA46_RS02505 (LXA46_02500) - 514396..515200 (+) 805 WP_100214365.1 IS5 family transposase -
  LXA46_RS02510 (LXA46_02505) blpM 515350..515604 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  LXA46_RS02515 (LXA46_02510) blpN 515620..515823 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  LXA46_RS02520 (LXA46_02515) cipB 516067..516216 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator
  LXA46_RS02525 (LXA46_02520) - 516320..516439 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=639384 LXA46_RS11010 WP_000205166.1 511108..511695(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=639384 LXA46_RS11010 WP_000205166.1 511108..511695(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497