Detailed information NTG0638641

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: EIH17_RS09995
• Genome accession: NZ_CP089782
• Coordinates: 1955160..1957307 (+)
• Length: 715 a.a.
• NCBI ID: WP_096638837.1
• Uniprot ID: -
• Organism: Leuconostoc mesenteroides strain KNU-2
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1950160..1962307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EIH17_RS09955	-	1950941..1951666 (+)	726	WP_232683749.1	response regulator transcription factor	-
EIH17_RS09960	-	1951938..1952150 (-)	213	WP_011679067.1	hypothetical protein	-
EIH17_RS09965	-	1952156..1952329 (-)	174	WP_072612884.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
EIH17_RS09970	-	1952343..1952522 (-)	180	WP_036089377.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
EIH17_RS09975	-	1953333..1953509 (-)	177	WP_096638841.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
EIH17_RS09980	-	1953730..1953915 (-)	186	WP_096638840.1	hypothetical protein	-
EIH17_RS09985	-	1954114..1954278 (-)	165	WP_096638839.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
EIH17_RS09990	-	1954271..1954471 (-)	201	WP_036089375.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
EIH17_RS09995	comA	1955160..1957307 (+)	2148	WP_096638837.1	peptide cleavage/export ABC transporter	Regulator
EIH17_RS10000	-	1957325..1958674 (+)	1350	WP_179876353.1	bacteriocin secretion accessory protein	-
EIH17_RS10005	-	1959491..1959616 (-)	126	WP_011679061.1	putative metal homeostasis protein	-
EIH17_RS10010	-	1959799..1960470 (-)	672	WP_115230863.1	SDR family NAD(P)-dependent oxidoreductase	-
EIH17_RS10015	-	1960528..1961115 (-)	588	WP_115230862.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80350.34 Da
• Isoelectric Point: 9.2370

>NTDB_id=638641 EIH17_RS09995 WP_096638837.1 1955160..1957307(+) (comA) [Leuconostoc mesenteroides strain KNU-2]
MRKFHYISQLEEKDCGVAALAMILKRHGSDVSLANIRERCQTSLSGTTALGLVKAAESFNMDVRPIQADLTLFNMKDLPL
PFIAHVEKKGQYLHYYVVYGFTKNKVIIADPDPTVAKTAMTLQEFSKEWTGVALFMSPSPRYKPFKENKNSILSFLPIIS
RQKGLIANIVVASLLVTLISIAGSYYMQLVIDAYIPSAMSNTLTVVSLGLIATYVLQQLLSFARTYLLTIMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANTIIDAMANTILSLFLDLGITIIVGSVLAIQNTKLFLLSLISFPIYFLIV
YCFMKPFERLNQEQMASNATLSSSIIEDINGIETIKSLTSEKTSYQKIDREFVDYLKKSFAHQKSEAIQNSIKQATQLII
NVLVLWLGAKLVISNQISVGQLVTYNALLGYFTEPFQNIINLQAKLQTATVANRRLNEVYLVKSEFKKSESQELHHNNPH
NIIVDDVSYQYGYQKNILHHFSIKIPFGEKIALVGVSGSGKSTLAKLLVHFISPSAGNIFIGEQNIKHVQRQNLRQHILY
LPQNPYIFTGSILDNLTLGARENTTQEDILHAVELADIKDDIENMPQSYQTEISEEGGMSGGQKQRIALARALLSNSQIL
ILDESTSNLDVATEKKIIDNLLSLKNKTIIFIAHRLTIAEKVQRVILLEKGIISEDGSHAELIHKKSKYYHLVKH

Nucleotide

• Length: 2148 bp

>NTDB_id=638641 EIH17_RS09995 WP_096638837.1 1955160..1957307(+) (comA) [Leuconostoc mesenteroides strain KNU-2]
ATGAGAAAGTTTCATTATATATCACAACTTGAAGAAAAAGATTGTGGCGTAGCAGCACTAGCTATGATTTTAAAGCGACA
CGGCTCAGATGTTTCATTAGCTAACATTCGTGAACGCTGTCAAACATCCCTATCGGGTACAACGGCGCTAGGCTTAGTGA
AGGCCGCTGAATCATTCAATATGGATGTCCGTCCTATTCAAGCTGACCTTACCTTATTCAACATGAAAGATTTGCCTCTG
CCGTTCATCGCTCATGTTGAGAAAAAAGGTCAATATTTGCATTATTATGTAGTGTACGGATTCACTAAAAACAAAGTTAT
CATTGCAGATCCAGATCCAACAGTTGCTAAAACCGCAATGACGTTACAAGAATTCTCTAAAGAGTGGACTGGTGTAGCAT
TGTTCATGTCGCCTTCACCCAGATATAAACCTTTTAAAGAAAATAAAAACAGTATCCTATCCTTTCTGCCAATTATTAGT
CGACAAAAAGGATTAATTGCTAATATTGTCGTCGCTTCTTTGCTAGTCACTTTAATTAGTATCGCTGGCTCTTATTATAT
GCAACTAGTGATTGATGCTTATATTCCTAGTGCTATGTCTAACACATTAACCGTTGTTTCATTAGGACTCATTGCCACCT
ATGTGTTACAACAGCTACTTAGTTTTGCTCGCACCTATCTGTTAACTATTATGGGACAACGATTATCGATTGAAGTCATA
CTATCATACATACGGCACTTGTTCGAATTACCTGTTAATTTCTTTGCCACACGTCGAACAGGTGAAATTGTCACGCGTTT
TAATGACGCCAACACCATTATTGATGCCATGGCAAATACAATTCTCTCACTTTTTTTAGATTTAGGTATCACGATAATTG
TTGGCAGCGTCTTAGCAATTCAAAATACAAAACTTTTTCTGCTATCTCTAATCTCTTTTCCTATCTACTTCTTGATTGTC
TATTGTTTCATGAAGCCATTTGAACGATTGAATCAAGAACAGATGGCAAGTAATGCAACGCTGAGCTCATCTATTATTGA
AGACATCAATGGTATTGAAACCATAAAATCTTTGACAAGCGAGAAGACGAGCTACCAAAAAATTGATCGTGAATTTGTCG
ATTATTTAAAAAAATCCTTTGCCCATCAAAAAAGCGAAGCCATTCAAAATAGTATTAAACAAGCAACTCAACTCATTATC
AATGTGCTCGTTTTATGGTTGGGTGCCAAGCTAGTGATTAGTAATCAAATTAGTGTCGGTCAGTTAGTTACCTATAATGC
ATTACTAGGCTACTTTACTGAACCTTTCCAAAATATTATTAACTTGCAGGCGAAATTACAAACGGCAACGGTTGCTAACC
GACGATTAAACGAAGTCTATCTTGTAAAATCAGAGTTTAAAAAATCAGAATCACAAGAGCTTCATCATAACAACCCTCAT
AACATTATAGTTGACGACGTCAGCTATCAATATGGTTATCAAAAGAACATATTACACCACTTTTCAATTAAGATCCCCTT
TGGTGAAAAAATTGCTCTGGTCGGTGTTAGCGGTTCCGGTAAGTCAACATTAGCCAAACTACTTGTTCATTTTATATCTC
CTAGTGCTGGCAACATTTTTATTGGTGAACAAAACATTAAACACGTTCAACGACAAAATTTAAGGCAACATATTCTTTAT
CTACCACAAAACCCATACATATTTACTGGAAGCATATTAGATAATTTAACACTAGGTGCTCGTGAAAACACAACACAAGA
AGACATCCTACATGCTGTTGAGCTTGCTGACATTAAAGATGACATCGAAAATATGCCACAAAGTTATCAAACCGAAATTT
CAGAGGAAGGCGGCATGTCTGGAGGCCAAAAGCAGCGTATCGCTTTAGCTAGAGCCCTCCTTAGTAATTCTCAAATACTT
ATTTTGGATGAATCAACCAGTAATCTTGATGTCGCAACTGAAAAAAAGATTATTGATAATTTATTATCGCTTAAAAATAA
AACAATCATTTTTATTGCACATCGCCTGACTATTGCTGAAAAAGTCCAACGCGTTATTCTGCTTGAAAAAGGGATCATCA
GTGAAGATGGTAGCCATGCTGAACTTATACATAAAAAATCAAAATACTATCATCTTGTAAAGCATTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (168-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	59.944	99.86	0.599
comA	Streptococcus mitis NCTC 12261	58.146	99.58	0.579
comA	Streptococcus mitis SK321	57.865	99.58	0.576
comA	Streptococcus pneumoniae Rx1	57.584	99.58	0.573
comA	Streptococcus pneumoniae D39	57.584	99.58	0.573
comA	Streptococcus pneumoniae R6	57.584	99.58	0.573
comA	Streptococcus pneumoniae TIGR4	57.303	99.58	0.571
comA/nlmT	Streptococcus mutans UA159	54.29	99.441	0.54