Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LQ049_RS11575 Genome accession   NZ_CP088187
Coordinates   2451530..2452816 (+) Length   428 a.a.
NCBI ID   WP_088774953.1    Uniprot ID   -
Organism   Enterococcus hirae strain S46-3     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2446530..2457816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LQ049_RS11555 (LQ049_11560) - 2446945..2447406 (-) 462 WP_088775426.1 PTS sugar transporter subunit IIA -
  LQ049_RS11560 (LQ049_11565) - 2447408..2449351 (-) 1944 WP_088775427.1 PRD domain-containing protein -
  LQ049_RS11565 (LQ049_11570) - 2449519..2450472 (-) 954 WP_060799069.1 IS30 family transposase -
  LQ049_RS11570 (LQ049_11575) rlmH 2450598..2451077 (-) 480 WP_002317110.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LQ049_RS11575 (LQ049_11580) htrA 2451530..2452816 (+) 1287 WP_088774953.1 trypsin-like peptidase domain-containing protein Regulator
  LQ049_RS11580 (LQ049_11585) ytpR 2452874..2453479 (-) 606 WP_088774954.1 YtpR family tRNA-binding protein -
  LQ049_RS11585 (LQ049_11590) - 2453789..2454256 (-) 468 WP_002317107.1 universal stress protein -
  LQ049_RS11590 (LQ049_11595) - 2454286..2454606 (-) 321 WP_002317106.1 thioredoxin family protein -
  LQ049_RS11595 (LQ049_11600) pepA 2455021..2456100 (-) 1080 WP_010720947.1 glutamyl aminopeptidase -
  LQ049_RS11600 (LQ049_11605) - 2456299..2456652 (+) 354 WP_002317104.1 PepSY domain-containing protein -
  LQ049_RS11605 (LQ049_11610) - 2456824..2457780 (+) 957 WP_002317103.1 glycosyltransferase family 2 protein -

Sequence

Protein


Download         Length: 428 a.a.        Molecular weight: 44609.73 Da        Isoelectric Point: 4.7976

>NTDB_id=633108 LQ049_RS11575 WP_088774953.1 2451530..2452816(+) (htrA) [Enterococcus hirae strain S46-3]
MERKDVTPKMKKNNGIWRKLGLGLVGGIIGGLVTAGIFYAVMGSGNAVSNSGGHQNSAGETVVENVKVNVDSDITNAVDK
VQDAVVSVINLQSQNQGTNGFGQLFGQQQQESSDDSNLEASSEGSGVIYKKSGNSAYIVTNNHVVEGQQGLEVLLKDGTK
VKAELVGTDAYSDLAVLKISADKVNKVASFGDSNSLKVGEPAIAIGSPLGSEYANSVTSGIISSLNRQVTSTNESNQTVN
INAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSASSSGVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITM
VDLSAVSTQQQEQILKIPESVTNGVIVTSVQPATPAEKAGLKQYDVITKIDDTDVSSGVELQSVLYQKKVGDSVKVTYYR
GKEKKTTTIQLTIDQSALKQSQSENSGN

Nucleotide


Download         Length: 1287 bp        

>NTDB_id=633108 LQ049_RS11575 WP_088774953.1 2451530..2452816(+) (htrA) [Enterococcus hirae strain S46-3]
ATGGAGAGAAAAGATGTGACACCAAAAATGAAAAAGAATAATGGAATCTGGCGTAAGCTGGGTCTAGGCTTAGTCGGTGG
AATTATTGGGGGCTTGGTAACGGCTGGTATTTTTTATGCTGTCATGGGTTCTGGAAACGCAGTGTCAAATTCGGGTGGTC
ATCAAAATTCAGCGGGCGAAACTGTCGTTGAGAATGTCAAAGTCAATGTCGATTCAGATATTACGAATGCGGTCGATAAA
GTCCAAGATGCGGTGGTATCTGTTATCAATCTTCAAAGCCAAAATCAAGGGACCAACGGCTTCGGGCAACTGTTTGGCCA
ACAACAACAAGAAAGTTCTGATGATAGCAATCTAGAGGCTTCTAGTGAAGGTAGTGGTGTCATCTACAAAAAAAGTGGTA
ATTCCGCTTATATCGTAACGAATAATCACGTAGTAGAAGGGCAACAAGGATTAGAAGTTTTATTAAAAGATGGTACAAAA
GTCAAAGCTGAATTAGTCGGGACGGATGCTTATTCTGACTTAGCCGTTTTGAAAATCAGTGCAGATAAAGTGAACAAAGT
TGCTTCATTTGGTGACTCTAATTCATTGAAAGTAGGTGAACCTGCGATCGCAATTGGTTCTCCTCTAGGTTCTGAATATG
CCAACTCTGTGACTTCGGGGATTATCTCTTCATTGAATCGCCAAGTAACCAGCACGAACGAGTCAAATCAAACGGTCAAT
ATCAATGCGATCCAAACAGATGCTGCGATTAACCCTGGTAATTCTGGTGGTCCATTAGTTAATATTGAAGGTCAAGTGAT
CGGGATCAATTCAAGTAAAATTGCAAGTACTTCTGCTTCTTCATCAGGTGTAAGCGTGGAAGGAATGGGCTTTGCGATCC
CAAGTAACGATGTAGTAAATATTATCAACCAACTTGAAAAAGATGGAAAAGTAACCCGTCCTGCTCTAGGGATCACAATG
GTTGACCTTTCAGCCGTTTCAACCCAACAACAAGAACAAATCTTAAAAATTCCTGAGTCTGTGACAAATGGTGTGATTGT
TACCAGCGTTCAACCGGCGACACCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACAAAAATCGATGATACTG
ATGTTTCTTCTGGTGTAGAATTACAATCTGTCTTGTATCAGAAAAAAGTCGGCGATTCAGTGAAGGTCACTTACTATCGC
GGAAAAGAAAAGAAAACAACAACGATTCAATTAACAATTGATCAATCCGCATTAAAACAAAGCCAATCAGAGAACTCTGG
TAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(314-411)

Peptidase family M50 (Peptidase_M50)

(12-414)

Trypsin-like peptidase domain (Trypsin_2)

(124-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

54.545

92.523

0.505
  htrA Streptococcus gordonii str. Challis substr. CH1

53.35

94.159

0.502
  htrA Streptococcus pneumoniae Rx1

58.457

78.738

0.46
  htrA Streptococcus pneumoniae D39

58.457

78.738

0.46
  htrA Streptococcus pneumoniae R6

58.457

78.738

0.46
  htrA Streptococcus pneumoniae TIGR4

58.457

78.738

0.46
  htrA Streptococcus mitis NCTC 12261

57.567

78.738

0.453