Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   N5O74_RS22575 Genome accession   NZ_CP104509
Coordinates   4462237..4463361 (-) Length   374 a.a.
NCBI ID   WP_000228553.1    Uniprot ID   -
Organism   Escherichia coli strain E2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 4457237..4468361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5O74_RS22545 (N5O74_22545) yrdA 4459037..4459591 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  N5O74_RS22550 (N5O74_22550) yrdB 4459567..4459824 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  N5O74_RS22555 (N5O74_22555) aroE 4459821..4460639 (-) 819 WP_000451243.1 shikimate dehydrogenase -
  N5O74_RS22560 (N5O74_22560) tsaC 4460644..4461216 (-) 573 WP_001301412.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  N5O74_RS22565 (N5O74_22565) yrdD 4461221..4461763 (-) 543 WP_001129722.1 type I DNA topoisomerase -
  N5O74_RS22570 (N5O74_22570) smg 4461792..4462265 (-) 474 WP_000460680.1 DUF494 family protein Smg -
  N5O74_RS22575 (N5O74_22575) dprA 4462237..4463361 (-) 1125 WP_000228553.1 DNA-protecting protein DprA Machinery gene
  N5O74_RS22580 (N5O74_22580) def 4463491..4464000 (+) 510 WP_000114984.1 peptide deformylase -
  N5O74_RS22585 (N5O74_22585) fmt 4464015..4464962 (+) 948 WP_000004473.1 methionyl-tRNA formyltransferase -
  N5O74_RS22590 (N5O74_22590) rsmB 4465008..4466297 (+) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  N5O74_RS22595 (N5O74_22595) trkA 4466319..4467695 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  N5O74_RS22600 (N5O74_22600) mscL 4467825..4468235 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40944.88 Da        Isoelectric Point: 6.3122

>NTDB_id=630115 N5O74_RS22575 WP_000228553.1 4462237..4463361(-) (dprA) [Escherichia coli strain E2]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFSRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=630115 N5O74_RS22575 WP_000228553.1 4462237..4463361(-) (dprA) [Escherichia coli strain E2]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCTCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.967

98.663

0.473
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Haemophilus influenzae Rd KW20

44.807

90.107

0.404
  dprA Glaesserella parasuis strain SC1401

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388