Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   N596_RS08925 Genome accession   NC_022584
Coordinates   1877635..1878381 (+) Length   248 a.a.
NCBI ID   WP_023022206.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1872635..1883381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS08910 (N596_09175) - 1872735..1874297 (-) 1563 WP_023027692.1 ABC transporter substrate-binding protein/permease -
  N596_RS08915 (N596_09180) - 1874417..1876324 (+) 1908 WP_023027693.1 DUF2207 domain-containing protein -
  N596_RS08920 (N596_09185) - 1876634..1877470 (+) 837 WP_023022205.1 undecaprenyl-diphosphate phosphatase -
  N596_RS08925 (N596_09190) mecA 1877635..1878381 (+) 747 WP_023022206.1 adaptor protein MecA Regulator
  N596_RS08930 (N596_09195) - 1878378..1879535 (+) 1158 WP_023027694.1 glycosyltransferase family 4 protein -
  N596_RS08935 (N596_09200) sufC 1879622..1880392 (+) 771 WP_023027695.1 Fe-S cluster assembly ATPase SufC -
  N596_RS08940 (N596_09205) sufD 1880434..1881696 (+) 1263 WP_023027696.1 Fe-S cluster assembly protein SufD -
  N596_RS08945 (N596_09210) - 1881699..1882925 (+) 1227 WP_023027697.1 cysteine desulfurase -
  N596_RS08950 (N596_09215) sufU 1882912..1883346 (+) 435 WP_023027698.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28844.49 Da        Isoelectric Point: 4.0873

>NTDB_id=62982 N596_RS08925 WP_023022206.1 1877635..1878381(+) (mecA) [Streptococcus ilei]
MKMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQHLNFEDFSDLPDMEELSQMSPDEFIKTLEKTISEKSKGDGDAIRHLEAEELADENQISEEDTSNHPVDTRYIYYILQF
SQLEEVIRFTKTVHYAVETSELYKMDGMYYLTILIDLEGCPQDYPGWLLATMREYAEDTDTTRAVLQEHGHLLLVSDAIH
ELQKVNLV

Nucleotide


Download         Length: 747 bp        

>NTDB_id=62982 N596_RS08925 WP_023022206.1 1877635..1878381(+) (mecA) [Streptococcus ilei]
ATGAAGATGAAGCAAATCAGTGATTCAACCATTAAAATCACGATTCAATTAGAGGACTTAGAAGAACGGGGCATGGAAAT
GGCCGATTTTTTGGTGCCTCAAGAAAAAACAGAAGAATTTTTCTATACCATCTTAGATGAATTAGAAATGCCAGAAAGTT
TCTTAGACAGTGGTATGTTAAGTTTCCGAGTGACCCCTAAGCCAGATAAACTCGATGTTTTTGTGACCAAATCAAAAATT
GATCAGCATTTAAATTTTGAAGATTTTTCCGACTTGCCTGATATGGAAGAATTGTCGCAAATGTCTCCAGACGAATTTAT
CAAAACCTTGGAAAAAACCATCTCTGAAAAGAGTAAGGGAGACGGCGATGCGATCCGTCATTTAGAAGCTGAGGAATTGG
CTGACGAAAATCAGATTTCAGAAGAAGATACATCGAATCATCCAGTAGATACACGGTATATTTATTATATCCTCCAGTTT
TCTCAGTTAGAAGAAGTGATTCGGTTTACAAAAACAGTTCATTATGCTGTTGAGACTTCTGAACTTTATAAAATGGACGG
GATGTACTATTTAACCATCCTGATCGATTTGGAAGGGTGTCCGCAGGATTATCCAGGTTGGCTTTTGGCAACTATGCGTG
AATATGCGGAAGATACAGATACTACTAGAGCTGTCCTTCAGGAACATGGCCATCTCTTGCTTGTCTCAGATGCTATTCAC
GAACTTCAAAAGGTTAATTTGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.26

99.194

0.657
  mecA Streptococcus pneumoniae D39

66.26

99.194

0.657
  mecA Streptococcus pneumoniae R6

66.26

99.194

0.657
  mecA Streptococcus pneumoniae TIGR4

66.26

99.194

0.657
  mecA Streptococcus mutans UA159

50.8

100

0.512
  mecA Streptococcus thermophilus LMD-9

46.185

100

0.464
  mecA Streptococcus thermophilus LMG 18311

45.783

100

0.46

Multiple sequence alignment