Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   N597_RS02480 Genome accession   NC_022582
Coordinates   476893..479133 (+) Length   746 a.a.
NCBI ID   WP_023022674.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 471893..484133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N597_RS02460 (N597_02550) - 472063..472809 (-) 747 WP_023022667.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  N597_RS02465 (N597_02555) - 472909..475248 (-) 2340 WP_042507440.1 cation-translocating P-type ATPase -
  N597_RS02470 (N597_02560) - 475386..476129 (+) 744 WP_023022671.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  N597_RS02475 (N597_02565) comEA/celA/cilE 476232..476909 (+) 678 WP_023022673.1 helix-hairpin-helix domain-containing protein Machinery gene
  N597_RS02480 (N597_02570) comEC/celB 476893..479133 (+) 2241 WP_023022674.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  N597_RS02485 (N597_02575) - 479196..479861 (+) 666 WP_023022676.1 DUF805 domain-containing protein -
  N597_RS02490 (N597_02580) holA 479839..480876 (+) 1038 WP_023022678.1 DNA polymerase III subunit delta -
  N597_RS02495 (N597_02585) sodA 480948..481553 (+) 606 WP_023022680.1 superoxide dismutase SodA -
  N597_RS02500 (N597_02590) - 481808..483280 (+) 1473 WP_023022682.1 helicase HerA-like domain-containing protein -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 85888.59 Da        Isoelectric Point: 9.5929

>NTDB_id=62903 N597_RS02480 WP_023022674.1 476893..479133(+) (comEC/celB) [Streptococcus ilei]
MLQWIRSINIHPFHLTLPVLALYYWMYTGHLLAPIFLLAFFILFSRRYNGKQFLILVGLLLFAALCFAFRVEHGKQEARD
QEVPRVIQLLPDTIKVNGDTLSFRAQSGSRTFQVFYQLQTKEEQAYFKHLDHGLELRIKGELETPTKQRNFMGFDYQAYL
KTQGIYHLLKISQILEKRPAEPRDLIGLLSSWRRKALVWVHQHFPQPMSHYMTGLLFGFLDVEFEEMSQLYSNLGIIHLF
ALSGMQVAFFLDAFRRFFLRLGLEQEKVATLLYPFSLLYAGMTGFSVSVVRSLIQKLLAQQGLKGMENMGMTLLLLLLFL
PSSLLTAGGLLSCAYAFILTLTSSEEEKSGIRKVVKESLVLTLGVLPFLIFFFGEYQPWSLPLTFVFSLLFDVLLLPGLS
VVFLLSFLYPLNFWNPFFIWMEKSMEYIAGFTSQSLVFGQPSISFFLLLLFLLACLYEMRKVKKWRYLFLLLVCSVFALV
KHPLENEITIIDIGQGDSILLRDWRGKTILIDTGGKVDFGQKEAWRNRRSTSNAERTLLPYLKSRGIDQIDHMVLTHTDT
DHMGDLEVLAAKVSIKEINISKGSLKKDSFVRLLKRLNLPVKTLEAGDQLSIFDGSAEVLYPVEVGDGSNNDSLVLYGRF
YGWTFLFTGDLEEEGEKTLLARYPQLRVDVLKAGHHGSKGSSHPAFLRRIQAKIALISAGEKNRYQHPHQETLERFKELQ
MMVFRTDRQGAIRFRGWNQWKIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=62903 N597_RS02480 WP_023022674.1 476893..479133(+) (comEC/celB) [Streptococcus ilei]
ATGTTACAGTGGATTAGAAGCATCAATATTCATCCATTTCATCTGACTCTTCCCGTCTTGGCTCTTTATTATTGGATGTA
TACAGGTCACTTGCTCGCTCCAATCTTCCTTCTGGCCTTCTTCATCTTGTTTAGTAGACGCTACAATGGCAAACAATTTC
TAATCCTAGTAGGGCTTCTCTTGTTTGCTGCACTTTGTTTTGCTTTTCGAGTCGAACATGGTAAGCAGGAAGCGCGGGAT
CAAGAGGTTCCAAGGGTTATTCAGCTCTTACCAGATACTATCAAGGTGAATGGAGATACCTTATCCTTTCGTGCTCAGTC
AGGTAGTCGTACTTTTCAGGTTTTCTATCAGCTTCAGACAAAAGAAGAACAAGCCTATTTTAAACACTTGGATCATGGGC
TAGAATTAAGAATAAAAGGAGAATTAGAGACCCCGACAAAACAGCGAAATTTCATGGGCTTTGATTACCAGGCTTATCTG
AAAACACAAGGGATCTATCATCTTTTGAAAATCAGCCAGATCCTTGAAAAGAGACCGGCTGAACCTAGAGATTTAATAGG
CCTCCTGTCTAGTTGGAGGCGAAAGGCCCTTGTATGGGTTCACCAGCATTTCCCCCAGCCCATGAGTCACTATATGACGG
GCTTGCTTTTTGGTTTTTTAGATGTAGAGTTCGAAGAAATGAGTCAGCTGTATTCGAACTTGGGGATTATCCATCTGTTC
GCCTTGTCGGGCATGCAGGTCGCTTTCTTCTTAGATGCTTTTCGACGATTCTTTCTCCGCTTGGGATTGGAGCAGGAAAA
AGTTGCAACCCTCCTCTATCCGTTTTCGCTTCTTTATGCTGGGATGACAGGCTTTTCGGTTTCGGTCGTTCGAAGCCTTA
TACAGAAGCTTCTAGCCCAGCAAGGTCTCAAAGGAATGGAGAATATGGGGATGACCCTCCTCTTGTTGCTCCTTTTTCTG
CCTTCTTCATTATTGACTGCTGGAGGACTCTTATCTTGTGCCTACGCTTTTATATTGACACTAACCTCTTCCGAGGAGGA
GAAGTCAGGAATCCGAAAAGTCGTCAAGGAGAGTCTGGTGTTAACACTAGGGGTTCTTCCTTTTTTGATTTTTTTCTTTG
GAGAATACCAGCCCTGGTCTCTCCCTCTAACCTTTGTTTTTTCCCTCTTATTTGATGTCCTTTTGTTACCAGGATTGAGT
GTCGTCTTTCTCCTCTCGTTTCTATATCCATTGAACTTCTGGAATCCCTTCTTCATCTGGATGGAAAAAAGTATGGAATA
TATAGCAGGATTTACCAGTCAATCTTTGGTTTTTGGACAACCAAGTATTTCTTTCTTCCTCTTGCTGTTATTCTTATTGG
CTTGCCTCTATGAGATGCGAAAGGTTAAGAAGTGGAGATATCTTTTTCTACTCTTAGTCTGCTCCGTATTCGCCCTTGTG
AAGCATCCTTTAGAAAATGAGATTACCATCATTGATATTGGTCAAGGTGATAGTATTTTGCTACGTGATTGGCGAGGGAA
GACGATCCTAATTGATACAGGTGGAAAAGTGGACTTTGGCCAAAAGGAAGCATGGAGGAATCGGAGGTCTACTAGCAATG
CAGAACGGACCTTGCTTCCTTATCTCAAGAGTAGAGGGATTGACCAGATTGACCATATGGTTCTCACGCATACTGACACA
GATCATATGGGAGATTTGGAAGTCCTTGCGGCTAAGGTTAGCATTAAGGAAATCAACATTTCCAAGGGAAGCTTAAAAAA
AGACTCCTTTGTCCGTTTGCTCAAACGGTTAAACCTACCTGTAAAGACGCTGGAGGCCGGTGATCAACTGTCAATCTTTG
ATGGGAGTGCAGAAGTTCTCTATCCGGTAGAAGTAGGAGATGGAAGTAATAACGATTCCCTTGTTCTCTATGGCCGGTTT
TATGGTTGGACCTTCCTTTTTACAGGAGATTTAGAAGAAGAGGGAGAAAAGACCTTGTTAGCCCGCTATCCTCAACTGCG
CGTGGATGTATTAAAAGCAGGGCACCATGGTTCTAAGGGCTCTTCTCACCCAGCCTTCTTAAGGCGAATCCAAGCAAAAA
TTGCCTTGATATCTGCGGGAGAAAAAAATCGTTACCAGCATCCTCATCAGGAAACCTTGGAGCGATTTAAAGAGTTGCAG
ATGATGGTTTTTCGGACAGATCGGCAAGGAGCGATTCGTTTTAGAGGATGGAATCAGTGGAAGATTGAAACCGTTCGATA
A

Domains

Predicted by InterproScan.

Competence protein (Competence)

(215-457)

Domain of unknown function (DUF4131) (DUF4131)

(32-174)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

52.4

100

0.527
  comEC/celB Streptococcus mitis SK321

51.995

100

0.524
  comEC/celB Streptococcus pneumoniae TIGR4

51.664

100

0.52
  comEC/celB Streptococcus pneumoniae Rx1

51.398

100

0.517
  comEC/celB Streptococcus pneumoniae D39

51.398

100

0.517
  comEC/celB Streptococcus pneumoniae R6

51.398

100

0.517
  comEC Lactococcus lactis subsp. cremoris KW2

44.595

99.196

0.442

Multiple sequence alignment