Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   N597_RS01575 Genome accession   NC_022582
Coordinates   316900..318771 (+) Length   623 a.a.
NCBI ID   WP_023022354.1    Uniprot ID   A0A3A5Q165
Organism   Streptococcus ilei     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 311900..323771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N597_RS01560 (N597_01615) fmt 313903..314838 (+) 936 WP_042507435.1 methionyl-tRNA formyltransferase -
  N597_RS01565 (N597_01620) rsmB 314828..316141 (+) 1314 WP_023022350.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  N597_RS01570 (N597_01625) - 316163..316903 (+) 741 WP_023022352.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  N597_RS01575 (N597_01630) stkP 316900..318771 (+) 1872 WP_023022354.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  N597_RS01580 (N597_01635) liaF 318902..319597 (+) 696 WP_023022357.1 cell wall-active antibiotics response protein LiaF -
  N597_RS01585 (N597_01640) - 319594..320613 (+) 1020 WP_023022359.1 sensor histidine kinase -
  N597_RS01590 (N597_01645) - 320591..321223 (+) 633 WP_023022361.1 response regulator transcription factor -
  N597_RS01595 (N597_01650) - 321268..322674 (+) 1407 WP_023022363.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  N597_RS01600 (N597_01655) - 322671..323039 (+) 369 WP_023022365.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 68472.73 Da        Isoelectric Point: 5.4911

>NTDB_id=62894 N597_RS01575 WP_023022354.1 316900..318771(+) (stkP) [Streptococcus ilei]
MIQIGKIFAGRYKIIRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTQGIIHRDLKPQNVLLTPDGNAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKASVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIEENKNVP
QALENVVIKATAKKLSDRYKSVAEMYVDLSSCLSYERRNEKKLVFDDASKADTKTLPKVNVVPKPTPLPTSDVRPVVHED
LPGASEDRTVPVSPKNKPRRRLRTRYKVLFVALALVLAAFAFLLYMSPANKTVPDVSGKTVAEARAIIEDQNLQVGDEKE
EYSDSVLEGYVIRTNPNAGAQKKEKSKVDLVVSKGPSTFDMPDYTGMSRENAENDLKTNYKLSSKLISIEEVETNEVEPG
IVIEQSPVAGQKYDLTSNTKVVLKVSKESNSIDLPSYVGSDYEFAVSNLVEIYGVKEANIERKTTSHLPAGVEVLPGQIV
SQTPEAQSSIDIKKTRIVLTVYEPKTEPSSSTKASSSSSEGSTSTTVESHSNTESSAITEPEP

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=62894 N597_RS01575 WP_023022354.1 316900..318771(+) (stkP) [Streptococcus ilei]
ATGATTCAAATCGGCAAAATTTTTGCCGGACGATATAAGATAATCCGCCAAATCGGGCGTGGAGGGATGGCAGATGTCTA
TCTCGCTCGGGATTTAATCTTAGATGGTGAAGAAGTTGCAGTTAAAGTACTGAGGACCAATTACCAAACAGATCCAATTG
CAGTTGCTCGCTTCCAACGAGAGGCTAAAGCGATGGCAGATTTGGATCATCCAAATATCGTTCGGATCACGGATATCGGT
GAAGAGGAAGGCCAACAATACTTGGCGATGGAATATGTCGCTGGCTTAGACTTGAAACGTTATATCAAGGAAAATGCTCC
TCTTTCAAATGAAGAAGCCGTTCGCTTGATGGGGCAAATCCTTCTTGCTATGCGCTTGGCGCACACGCAAGGGATTATTC
ACCGTGACTTAAAGCCTCAAAACGTTCTTTTAACACCAGATGGAAATGCCAAGGTCTCTGACTTTGGGATTGCGGTAGCC
TTTGCAGAAACGAGTCTCACTCAGACAAACTCTATGTTGGGATCGGTTCATTATTTGTCTCCTGAACAAGCTAGAGGATC
GAAAGCTTCTGTTCAAAGCGATATTTATGCAATGGGGATTATATTCTACGAAATGCTGACGGGACATATCCCTTATGATG
GGGATAGTGCAGTGACGATCGCGCTACAACATTTCCAAAAACCACTTCCGTCCATCATCGAAGAGAATAAAAATGTTCCA
CAGGCCTTGGAAAATGTGGTTATTAAAGCAACAGCAAAGAAACTATCCGATCGCTATAAGTCGGTAGCTGAAATGTATGT
TGACCTCTCTAGTTGCTTATCTTATGAGCGTCGTAACGAGAAAAAATTGGTCTTTGATGATGCTTCAAAAGCAGATACCA
AAACCCTACCAAAGGTAAACGTGGTTCCAAAACCAACGCCACTTCCAACATCAGATGTTCGTCCGGTTGTTCATGAGGAC
CTACCAGGGGCTTCAGAGGATAGAACGGTTCCAGTTTCTCCAAAAAATAAGCCACGTCGTCGTTTGAGGACACGCTACAA
AGTCTTGTTTGTTGCTTTAGCTTTGGTACTAGCTGCCTTTGCCTTTCTTCTTTATATGAGTCCAGCCAACAAAACAGTTC
CGGATGTATCTGGAAAAACTGTTGCAGAAGCTCGTGCTATCATTGAAGATCAGAATCTTCAAGTTGGAGACGAAAAAGAA
GAATACAGTGATTCTGTACTTGAAGGCTATGTGATTCGTACCAATCCAAATGCAGGAGCTCAGAAAAAAGAAAAAAGCAA
GGTTGATTTGGTTGTCTCGAAAGGACCAAGCACCTTTGATATGCCAGACTATACTGGTATGTCTAGAGAAAATGCAGAAA
ATGATCTGAAAACCAACTATAAGCTTTCTAGCAAACTCATTTCGATTGAAGAAGTCGAGACCAATGAAGTAGAACCAGGA
ATCGTTATTGAGCAATCTCCTGTCGCTGGTCAAAAATATGATTTGACTTCTAATACGAAGGTTGTTCTGAAAGTATCTAA
GGAAAGTAATTCTATCGATTTACCAAGTTATGTCGGTTCTGATTATGAGTTTGCTGTTTCTAATCTCGTTGAAATCTACG
GGGTGAAGGAAGCAAATATTGAACGGAAGACCACATCGCATCTTCCAGCTGGAGTAGAAGTCTTACCAGGTCAAATTGTG
AGTCAGACTCCGGAAGCTCAATCAAGCATCGATATTAAGAAGACTCGCATTGTCTTGACCGTGTACGAACCGAAGACGGA
ACCATCAAGTAGTACGAAAGCTTCAAGCAGTTCATCAGAAGGTTCAACCTCTACAACAGTGGAATCACATTCCAATACGG
AATCCTCAGCTATCACTGAACCAGAACCTTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-507)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(514-582)

Protein kinase domain (Pkinase)

(12-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3A5Q165

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.203

94.222

0.596
  stkP Streptococcus pneumoniae D39

63.032

94.222

0.594
  stkP Streptococcus pneumoniae R6

63.032

94.222

0.594
  stkP Streptococcus pneumoniae Rx1

62.862

94.222

0.592
  pknB Streptococcus mutans UA159

58.118

86.998

0.506
  stkP/pknB Streptococcus salivarius strain HSISS4

52.365

95.024

0.498

Multiple sequence alignment