Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   M5T11_RS02260 Genome accession   NZ_CP103762
Coordinates   479366..480490 (+) Length   374 a.a.
NCBI ID   WP_001521436.1    Uniprot ID   -
Organism   Escherichia coli strain 5283     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 474366..485490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5T11_RS02235 (M5T11_02235) mscL 474492..474902 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  M5T11_RS02240 (M5T11_02240) trkA 475032..476408 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  M5T11_RS02245 (M5T11_02245) rsmB 476430..477719 (-) 1290 WP_001308993.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M5T11_RS02250 (M5T11_02250) fmt 477765..478712 (-) 948 WP_000004456.1 methionyl-tRNA formyltransferase -
  M5T11_RS02255 (M5T11_02255) def 478727..479236 (-) 510 WP_000114984.1 peptide deformylase -
  M5T11_RS02260 (M5T11_02260) dprA 479366..480490 (+) 1125 WP_001521436.1 DNA-protecting protein DprA Machinery gene
  M5T11_RS02265 (M5T11_02265) smg 480462..480935 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  M5T11_RS02270 (M5T11_02270) yrdD 480964..481506 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  M5T11_RS02275 (M5T11_02275) tsaC 481511..482083 (+) 573 WP_029701540.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  M5T11_RS02280 (M5T11_02280) aroE 482088..482906 (+) 819 WP_001521434.1 shikimate dehydrogenase -
  M5T11_RS02285 (M5T11_02285) yrdB 482903..483160 (+) 258 WP_001521433.1 DUF1488 domain-containing protein -
  M5T11_RS02290 (M5T11_02290) yrdA 483136..483690 (-) 555 WP_001286217.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40994.94 Da        Isoelectric Point: 6.2655

>NTDB_id=625010 M5T11_RS02260 WP_001521436.1 479366..480490(+) (dprA) [Escherichia coli strain 5283]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=625010 M5T11_RS02260 WP_001521436.1 479366..480490(+) (dprA) [Escherichia coli strain 5283]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.71

82.888

0.404
  dprA Vibrio cholerae strain A1552

48.71

82.888

0.404
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388