Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LMK00_RS10720 Genome accession   NZ_CP086395
Coordinates   2167548..2168765 (+) Length   405 a.a.
NCBI ID   WP_017369969.1    Uniprot ID   A0A9Q9D6R4
Organism   Lactococcus formosensis strain I4/6O     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2162548..2173765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LMK00_RS10690 (LMK00_10685) eeP 2162563..2163810 (-) 1248 WP_252175442.1 RIP metalloprotease RseP Regulator
  LMK00_RS10695 (LMK00_10690) - 2163987..2164781 (-) 795 WP_017369964.1 phosphatidate cytidylyltransferase -
  LMK00_RS10700 (LMK00_10695) - 2164778..2165515 (-) 738 WP_096368979.1 isoprenyl transferase -
  LMK00_RS10705 (LMK00_10700) yajC 2165714..2166046 (-) 333 WP_017369966.1 preprotein translocase subunit YajC -
  LMK00_RS10710 (LMK00_10705) - 2166121..2166768 (-) 648 WP_252175443.1 DNA alkylation repair protein -
  LMK00_RS10715 (LMK00_10710) rlmH 2166765..2167244 (-) 480 WP_017369968.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LMK00_RS10720 (LMK00_10715) htrA 2167548..2168765 (+) 1218 WP_017369969.1 trypsin-like peptidase domain-containing protein Regulator
  LMK00_RS10725 (LMK00_10720) - 2168862..2169860 (+) 999 WP_252175444.1 glycosyltransferase family 4 protein -
  LMK00_RS10730 (LMK00_10725) - 2169873..2171207 (+) 1335 WP_252175445.1 glycosyltransferase family 4 protein -
  LMK00_RS10735 (LMK00_10730) - 2171258..2171482 (+) 225 WP_017369972.1 DUF1797 family protein -
  LMK00_RS10740 (LMK00_10735) - 2171514..2172563 (-) 1050 WP_252175446.1 BMP family protein -
  LMK00_RS10745 (LMK00_10740) - 2172722..2173471 (-) 750 WP_017369975.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41850.60 Da        Isoelectric Point: 4.6948

>NTDB_id=624761 LMK00_RS10720 WP_017369969.1 2167548..2168765(+) (htrA) [Lactococcus formosensis strain I4/6O]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNSPQLSGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVQETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
DVTNGVAVAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATTNIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=624761 LMK00_RS10720 WP_017369969.1 2167548..2168765(+) (htrA) [Lactococcus formosensis strain I4/6O]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGGGGTAGTGCTATCTA
CCAAAACATGACTAACACGCCGTCATCTAATAATACTTCGGACAATTCTGTAAGTACAGTTAACGTACAAGTCAATACAG
ATACAACCAAAGCAATCAAGAAAATTTCAAACACTGTTGTTTCCGTACTTAATTACCAAAAATCGTCGTCAAGCAACGAC
TTTGAAAAGATTTTCGGCGGAGGCGACACAAGCAGCAATGAGAGTAACTCACCACAGCTATCTGGAGAAGGTTCTGGGGT
TATCTATAAAAAGGACGGCAATACCGCATACATCGTAACCAACTATCACGTTATTGAAGGTGCGTCTTCCTTAGAAGTTC
TCATGGCTGGTGGTCAAAAAGTAACTGCCGAAGTTGTTGGTTCCGATGCTTATTCGGATTTAGCTGTCCTCAAAATTGAT
GCCAAGTATGTTCAAGAAACAGCAACGTTCGGCAACTCTGACAAACTTACTGTTGGTGAACCTGCTATCGCCGTTGGTTC
TCCTCTTGGAAGTGAGTATGCTAACTCAGCAACAGAAGGTATTGTTTCAAGTCTTAATCGCAATGTTACACTGCAAAACA
GCCAAGGCCAAACCATTAATGTTAATGCTATTCAAACCGATGCAGCGATTAACCCTGGTAACTCTGGTGGTGCACTCATC
AATATACAAGGACAAGTCATCGGGATTACTTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGTAGCAGCGGTGTCTC
TGTAGAAGGCATGGGGTTTGCGATTCCAGCCAATGATGTCGTCAATATTATCAATAAATTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTGGGTGTGCAAATGGTTAACCTATCAAGTCTTTCACAAAATATGTTGGCTTCACTTAACCTTCCTGAA
GACGTGACGAACGGTGTTGCTGTCGCTGAAGTTCAATCTGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTGAACCTTCAAAGCACACTTTATAAATCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTACAAATATCAAGTTAGATAAAACAAGTAGTGATATCAAT
TTTGACAAGCAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.878

93.333

0.531
  htrA Streptococcus mitis NCTC 12261

53.634

98.519

0.528
  htrA Streptococcus pneumoniae Rx1

53.383

98.519

0.526
  htrA Streptococcus pneumoniae D39

53.383

98.519

0.526
  htrA Streptococcus pneumoniae R6

53.383

98.519

0.526
  htrA Streptococcus pneumoniae TIGR4

53.383

98.519

0.526
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

96.543

0.523