Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   M5S78_RS02195 Genome accession   NZ_CP103626
Coordinates   452979..454103 (+) Length   374 a.a.
NCBI ID   WP_069354151.1    Uniprot ID   -
Organism   Escherichia coli strain 4012     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 447979..459103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5S78_RS02170 (M5S78_02170) mscL 448105..448515 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  M5S78_RS02175 (M5S78_02175) trkA 448645..450021 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  M5S78_RS02180 (M5S78_02180) rsmB 450043..451332 (-) 1290 WP_001323790.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M5S78_RS02185 (M5S78_02185) fmt 451378..452325 (-) 948 WP_000004454.1 methionyl-tRNA formyltransferase -
  M5S78_RS02190 (M5S78_02190) def 452340..452849 (-) 510 WP_000114984.1 peptide deformylase -
  M5S78_RS02195 (M5S78_02195) dprA 452979..454103 (+) 1125 WP_069354151.1 DNA-protecting protein DprA Machinery gene
  M5S78_RS02200 (M5S78_02200) smg 454075..454548 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  M5S78_RS02205 (M5S78_02205) yrdD 454577..455119 (+) 543 WP_001129719.1 type I DNA topoisomerase -
  M5S78_RS02210 (M5S78_02210) tsaC 455124..455696 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  M5S78_RS02215 (M5S78_02215) aroE 455701..456519 (+) 819 WP_000451239.1 shikimate dehydrogenase -
  M5S78_RS02220 (M5S78_02220) yrdB 456516..456773 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  M5S78_RS02225 (M5S78_02225) yrdA 456749..457303 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41002.02 Da        Isoelectric Point: 6.3837

>NTDB_id=623772 M5S78_RS02195 WP_069354151.1 452979..454103(+) (dprA) [Escherichia coli strain 4012]
MVDTDIWLRLMSISSLYGDDMVRIAHWLAKQPHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLVTTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=623772 M5S78_RS02195 WP_069354151.1 452979..454103(+) (dprA) [Escherichia coli strain 4012]
ATGGTCGATACAGATATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGCCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGTGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCTGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTCTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.385

100

0.444
  dprA Vibrio cholerae strain A1552

44.385

100

0.444
  dprA Haemophilus influenzae Rd KW20

45.401

90.107

0.409
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39