Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   KW2_RS10910 Genome accession   NC_022369
Coordinates   2260043..2261266 (+) Length   407 a.a.
NCBI ID   WP_021037958.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris KW2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2255043..2266266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KW2_RS10885 (kw2_2191) - 2256157..2256960 (-) 804 WP_011677190.1 phosphatidate cytidylyltransferase -
  KW2_RS10890 (kw2_2192) - 2256960..2257694 (-) 735 WP_011836054.1 isoprenyl transferase -
  KW2_RS10895 (kw2_2193) yajC 2258045..2258377 (-) 333 WP_011836055.1 preprotein translocase subunit YajC -
  KW2_RS10900 (kw2_2194) - 2258472..2259170 (-) 699 WP_021037956.1 DNA alkylation repair protein -
  KW2_RS10905 (kw2_2195) rlmH 2259188..2259667 (-) 480 WP_021037957.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KW2_RS10910 (kw2_2196) htrA 2260043..2261266 (+) 1224 WP_021037958.1 S1C family serine protease Regulator
  KW2_RS10915 (kw2_2197) - 2261387..2262385 (+) 999 WP_011836059.1 glycosyltransferase family 4 protein -
  KW2_RS10920 (kw2_2198) - 2262531..2263871 (+) 1341 WP_021037959.1 glycosyltransferase family 4 protein -
  KW2_RS10925 (kw2_2199) - 2263979..2264203 (+) 225 WP_003130579.1 YkuJ family protein -
  KW2_RS10930 (kw2_2200) - 2264348..2265352 (+) 1005 WP_021037960.1 hypothetical protein -
  KW2_RS10935 (kw2_2201) - 2265409..2266161 (-) 753 WP_021037961.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41526.97 Da        Isoelectric Point: 5.3802

>NTDB_id=62285 KW2_RS10910 WP_021037958.1 2260043..2261266(+) (htrA) [Lactococcus cremoris subsp. cremoris KW2]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYDEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGVVVYSVQAGLPAASAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=62285 KW2_RS10910 WP_021037958.1 2260043..2261266(+) (htrA) [Lactococcus cremoris subsp. cremoris KW2]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTCGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAATCGCTCAAATACGACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTTACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACGGCTTGCAACTTTCCAGTGAGGG
TTCTGGTGTTATTTATAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCTGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
GGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACCT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCTGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACTGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATTCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCTTTAGGTATCCGTATGGTTGACTTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGAGTGGTTGTCTACTCTGTTCAAGCGGGTCTTCCTGCTGCCTCAGCCGGTCTGAAAGCTGGCGATGTGAT
AACGAAAGTGGGAGATACCGCTGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

PDZ domain (PDZ_2)

(295-391)

Peptidase family M50 (Peptidase_M50)

(250-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

55.128

95.823

0.528
  htrA Streptococcus mitis NCTC 12261

55.875

94.103

0.526
  htrA Streptococcus pneumoniae Rx1

58.14

84.521

0.491
  htrA Streptococcus pneumoniae D39

58.14

84.521

0.491
  htrA Streptococcus pneumoniae R6

58.14

84.521

0.491
  htrA Streptococcus pneumoniae TIGR4

58.14

84.521

0.491
  htrA Streptococcus mutans UA159

53.388

90.663

0.484

Multiple sequence alignment