Detailed information NTG0622437

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LL046_RS09080
• Genome accession: NZ_CP086088
• Coordinates: 1812552..1814762 (-)
• Length: 736 a.a.
• NCBI ID: WP_058210776.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain EIP13A
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1807552..1819762

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL046_RS09050 (LL046_09030)	atpA	1807594..1809096 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
LL046_RS09055 (LL046_09035)	-	1809283..1809810 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
LL046_RS09060 (LL046_09040)	atpF	1809812..1810318 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
LL046_RS09065 (LL046_09045)	atpB	1810333..1811046 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
LL046_RS09070 (LL046_09050)	-	1811091..1811306 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
LL046_RS09075 (LL046_09055)	-	1811491..1812267 (-)	777	WP_017864911.1	alpha/beta hydrolase family protein	-
LL046_RS09080 (LL046_09060)	comEC	1812552..1814762 (-)	2211	WP_058210776.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LL046_RS09085 (LL046_09065)	comEA	1814743..1815390 (-)	648	WP_017864913.1	ComEA family DNA-binding protein	Machinery gene
LL046_RS09090 (LL046_09070)	-	1815450..1816811 (-)	1362	WP_017864914.1	ABC transporter permease	-
LL046_RS09095 (LL046_09075)	-	1816808..1817740 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LL046_RS09100 (LL046_09080)	-	1817846..1818244 (-)	399	WP_023188528.1	hypothetical protein	-
LL046_RS09105 (LL046_09085)	-	1818348..1818911 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84400.12 Da
• Isoelectric Point: 9.7369

>NTDB_id=622437 LL046_RS09080 WP_058210776.1 1812552..1814762(-) (comEC) [Lactococcus lactis subsp. lactis strain EIP13A]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTIGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKGRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=622437 LL046_RS09080 WP_058210776.1 1812552..1814762(-) (comEC) [Lactococcus lactis subsp. lactis strain EIP13A]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGTCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAATAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAGGAA
GACAAATAATTTTTGCAGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Competence protein (Competence) (206-446)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.902	100	0.769
comEC/celB	Streptococcus mitis SK321	44.474	100	0.448
comEC/celB	Streptococcus mitis NCTC 12261	44.34	100	0.447
comEC/celB	Streptococcus pneumoniae TIGR4	43.607	100	0.44
comEC/celB	Streptococcus pneumoniae Rx1	43.203	100	0.436
comEC/celB	Streptococcus pneumoniae D39	43.203	100	0.436
comEC/celB	Streptococcus pneumoniae R6	43.203	100	0.436