Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   M5S50_RS02235 Genome accession   NZ_CP103468
Coordinates   478007..479131 (+) Length   374 a.a.
NCBI ID   WP_000228569.1    Uniprot ID   -
Organism   Escherichia coli strain 4973     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 473007..484131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5S50_RS02210 (M5S50_02210) mscL 473133..473543 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  M5S50_RS02215 (M5S50_02215) trkA 473673..475049 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  M5S50_RS02220 (M5S50_02220) rsmB 475071..476360 (-) 1290 WP_001329571.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M5S50_RS02225 (M5S50_02225) fmt 476406..477353 (-) 948 WP_022646187.1 methionyl-tRNA formyltransferase -
  M5S50_RS02230 (M5S50_02230) def 477368..477877 (-) 510 WP_000114986.1 peptide deformylase -
  M5S50_RS02235 (M5S50_02235) dprA 478007..479131 (+) 1125 WP_000228569.1 DNA-protecting protein DprA Machinery gene
  M5S50_RS02240 (M5S50_02240) smg 479103..479576 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  M5S50_RS02245 (M5S50_02245) yrdD 479605..480147 (+) 543 WP_001129718.1 type I DNA topoisomerase -
  M5S50_RS02250 (M5S50_02250) tsaC 480152..480724 (+) 573 WP_001353637.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  M5S50_RS02255 (M5S50_02255) aroE 480729..481547 (+) 819 WP_000432883.1 shikimate dehydrogenase -
  M5S50_RS02260 (M5S50_02260) yrdB 481544..481801 (+) 258 WP_001070584.1 DUF1488 domain-containing protein -
  M5S50_RS02265 (M5S50_02265) yrdA 481777..482331 (-) 555 WP_022646186.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40916.82 Da        Isoelectric Point: 6.0395

>NTDB_id=622277 M5S50_RS02235 WP_000228569.1 478007..479131(+) (dprA) [Escherichia coli strain 4973]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLISADSE
FYPPQLLATTDYPGTLFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=622277 M5S50_RS02235 WP_000228569.1 478007..479131(+) (dprA) [Escherichia coli strain 4973]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCTCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCACACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACTATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAACAGGGTGGTGCTCTCGTCTCGGAATTTCCCCTTGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.826

98.396

0.471
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388