Detailed information NTG0621520

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: LK420_RS08220
• Genome accession: NZ_CP085949
• Coordinates: 1696315..1697658 (-)
• Length: 447 a.a.
• NCBI ID: WP_021034382.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain FDAARGOS_1562
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1691315..1702658

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK420_RS08190 (LK420_08190)	-	1692360..1692632 (-)	273	WP_005630954.1	HU family DNA-binding protein	-
LK420_RS08195 (LK420_08195)	-	1692771..1693361 (-)	591	WP_021034387.1	YjaG family protein	-
LK420_RS08200 (LK420_08200)	nudC	1693397..1694191 (-)	795	WP_021034386.1	NAD(+) diphosphatase	-
LK420_RS08205 (LK420_08205)	nfuA	1694259..1694855 (-)	597	WP_021034385.1	Fe-S biogenesis protein NfuA	-
LK420_RS08210 (LK420_08210)	-	1694931..1695617 (-)	687	WP_021034384.1	ComF family protein	-
LK420_RS08215 (LK420_08215)	tnpA	1695865..1696318 (-)	454	Protein_1574	IS200/IS605 family transposase	-
LK420_RS08220 (LK420_08220)	comE	1696315..1697658 (-)	1344	WP_021034382.1	type IV pilus secretin PilQ	Machinery gene
LK420_RS08225 (LK420_08225)	comD	1697668..1698081 (-)	414	WP_021034381.1	pilus assembly protein PilP	Machinery gene
LK420_RS08230 (LK420_08230)	comC	1698078..1698599 (-)	522	WP_021034380.1	hypothetical protein	Machinery gene
LK420_RS08235 (LK420_08235)	comB	1698596..1699102 (-)	507	WP_021034379.1	hypothetical protein	Machinery gene
LK420_RS08240 (LK420_08240)	comA	1699103..1699900 (-)	798	WP_021034378.1	pilus assembly protein PilM	Machinery gene
LK420_RS08245 (LK420_08245)	-	1699999..1702599 (+)	2601	WP_021034377.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 447 a.a.
• Molecular weight: 49516.68 Da
• Isoelectric Point: 6.7046

>NTDB_id=621520 LK420_RS08220 WP_021034382.1 1696315..1697658(-) (comE) [Haemophilus influenzae strain FDAARGOS_1562]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVIDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKWQVAGNLTTNEPHLESHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPHSVQNIKKLISEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVSYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide

• Length: 1344 bp

>NTDB_id=621520 LK420_RS08220 WP_021034382.1 1696315..1697658(-) (comE) [Haemophilus influenzae strain FDAARGOS_1562]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTCTGTTTTTGTTTACCCTTAATTGTTTTTGCTAATCCCAAAAC
TGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACATTAGAGCAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATAGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAGGCAAATG
GCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGAGAGCCATACAGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGACAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTCGTGATTCAAGATGAACCTCATTCTGTGCAAAATATCAAAAAACTAATTTCTGAAATGGATAAACCTATTGAGCA
GATTGCTATTGAAGCGCGTATTGTGACGATAACAGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACGGAAAATGCAAGACGAGTTGCGGGCAGTCTTGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACAACACCTGCTGGCTCGATAGCATTACAAGTCGCCAAAATTAATGGGCGATTGCTCGATTTAGAATT
GAGTGCGTTAGAGCGTGAAAATAATGTAGAAATTATCGCAAGCCCTCGCTTACTAACCACAAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTATATTGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGCGAGGCGGTG
CTTGGTTTGGAAGTCACACCACATATTTCTAAAGATAACAATATTTTACTTGATTTATTAGTGAGCCAAAACTCACCAGG
TTCTCGTGTTTCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTGTTTCACGACACAATTACGAAAAGCGAAGATAAGGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTCAGCAAAGAAAGCGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCGCATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAGCAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (123-187)

• Bacterial type II and III secretion system protein (Secretin) (269-429)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	95.955	99.553	0.955
comE	Haemophilus influenzae 86-028NP	95.73	99.553	0.953
comE	Glaesserella parasuis strain SC1401	52.941	95.078	0.503
pilQ	Vibrio campbellii strain DS40M4	42.959	93.736	0.403
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	42.233	92.17	0.389
pilQ	Vibrio cholerae strain A1552	42.233	92.17	0.389