Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   LK450_RS06900 Genome accession   NZ_CP085939
Coordinates   1404320..1405642 (+) Length   440 a.a.
NCBI ID   WP_221739197.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1399320..1410642
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK450_RS06870 (LK450_06870) dnaA 1399614..1400957 (-) 1344 WP_003032031.1 chromosomal replication initiator protein DnaA -
  LK450_RS06875 (LK450_06875) spo0J 1401186..1401953 (-) 768 WP_003032028.1 ParB/RepB/Spo0J family partition protein Regulator
  LK450_RS06880 (LK450_06880) htrA 1402008..1403198 (-) 1191 WP_003032033.1 S1C family serine protease Regulator
  LK450_RS06885 (LK450_06885) rlmH 1403392..1403871 (+) 480 WP_003032032.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LK450_RS06895 (LK450_06895) - 1404153..1404299 (+) 147 WP_003029519.1 bacteriocin -
  LK450_RS06900 (LK450_06900) comD/comD2 1404320..1405642 (+) 1323 WP_221739197.1 GHKL domain-containing protein Regulator
  LK450_RS06905 (LK450_06905) comE 1405642..1406391 (+) 750 WP_018543656.1 competence system response regulator transcription factor ComE Regulator
  LK450_RS06920 (LK450_06920) - 1406739..1409315 (-) 2577 WP_018543657.1 YfhO family protein -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51916.64 Da        Isoelectric Point: 8.4767

>NTDB_id=621421 LK450_RS06900 WP_221739197.1 1404320..1405642(+) (comD/comD2) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFSTDFTTLIHYSIRYMMFFIQPLFFYLYFFKVKKVK
KHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKIDFKENIVQL
NFYLLFIHLLLNVSHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLYN
EIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKTRDYNIELT
FEVKDFVNPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=621421 LK450_RS06900 WP_221739197.1 1404320..1405642(+) (comD/comD2) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
GTGAAAATAGAATTTATACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGCTATAAGAAAATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTCAACTGATTTCACTACTTTAATAC
ATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTTAAA
AAACACCTTTCTGTATTTTTAGCATTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTTTCA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGATAGATTTTAAAGAAAATATTGTACAATTA
AATTTTTATCTATTATTTATTCATCTTTTATTAAATGTATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTGTTCTACTTACAATCTATTCGCGAAAAGTATGAAA
AAGAAGAACAAATTAAACAAAAAGAACGAGAACAATTACAATTACAAAAATATACAGATGAAATTGTGAGTCTGTATAAT
GAAATTCGAGGCTTTCGCCATGATTATGGAGGAATGTTGGCAAGCTTCCAATCGGCCATTCATACAGGTGATATAAAAGA
AGTAGAGCGAATTTATCAGGAAGTACTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACACAAACCTTATTTAAGACGCGTGACTATAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTCAACCCCTTGCCGATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTCCTTTTAAATAA
TGCAATAGAGGGAGCGGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTAGTAGATCTGGATACAGAAACAATCTTAG
TTATTCAAAATTCACGTAAGAAACGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGGGTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.299

100

0.545
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

58.901

86.818

0.511
  comD Streptococcus mitis SK321

46.939

89.091

0.418
  comD Streptococcus mitis NCTC 12261

48.404

85.455

0.414
  comD/comD2 Streptococcus pneumoniae TIGR4

47.872

85.455

0.409
  comD/comD1 Streptococcus pneumoniae Rx1

47.34

85.455

0.405
  comD/comD1 Streptococcus pneumoniae D39

47.34

85.455

0.405
  comD/comD1 Streptococcus pneumoniae R6

47.34

85.455

0.405