Detailed information NTG0621408

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: LK450_RS04945
• Genome accession: NZ_CP085939
• Coordinates: 1018509..1020383 (-)
• Length: 624 a.a.
• NCBI ID: WP_018543640.1
• Uniprot ID: -
• Organism: Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Genomic Context

Location: 1013509..1025383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK450_RS04915 (LK450_04915)	-	1013665..1013982 (+)	318	WP_003031462.1	DUF960 domain-containing protein	-
LK450_RS04920 (LK450_04920)	-	1014108..1014482 (-)	375	WP_018543641.1	S1 RNA-binding domain-containing protein	-
LK450_RS04925 (LK450_04925)	-	1014484..1015884 (-)	1401	WP_003031456.1	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	-
LK450_RS04930 (LK450_04930)	-	1015924..1016556 (-)	633	WP_003031463.1	response regulator transcription factor	-
LK450_RS04935 (LK450_04935)	-	1016558..1017553 (-)	996	WP_003031470.1	sensor histidine kinase	-
LK450_RS04940 (LK450_04940)	liaF	1017550..1018248 (-)	699	WP_003025810.1	cell wall-active antibiotics response protein LiaF	-
LK450_RS04945 (LK450_04945)	stkP	1018509..1020383 (-)	1875	WP_018543640.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
LK450_RS04950 (LK450_04950)	-	1020380..1021120 (-)	741	WP_003031460.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
LK450_RS04955 (LK450_04955)	rsmB	1021139..1022452 (-)	1314	WP_003031466.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LK450_RS04960 (LK450_04960)	fmt	1022442..1023377 (-)	936	WP_003031468.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 624 a.a.
• Molecular weight: 67647.70 Da
• Isoelectric Point: 9.4135

>NTDB_id=621408 LK450_RS04945 WP_018543640.1 1018509..1020383(-) (stkP) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MIQVGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKSTPTPTKEAVS
SKPTPKPKAKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTP
AAGSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQTPEAGQS
LNLKSDRIVLYVYEPKTEDSSTSESSSQSDSSSDKTSPSSSSSSASGNDGSSSKTPDTSASASN

Nucleotide

• Length: 1875 bp

>NTDB_id=621408 LK450_RS04945 WP_018543640.1 1018509..1020383(-) (stkP) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAAAATCATCAAACAAATTGGTCGAGGTGGCATGGCAGATGTTTA
CTTGGCCAAAGATTTGATTTTAGACGGGGAAGAAGTCGCGGTTAAAGTTCTAAGAACGAATTATCAGACGGATCCGATTG
CTGTGGCGCGTTTTCAAAGAGAGGCGCGAGCTATGGCAGACTTGGATCATCCTCATATTGTTCGGATTACCGACATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAATATGTGGCTGGACTCGACTTAAAGCGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCACACACGCACGGGATTGTTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTCACTGACTTTGGAATTGCGGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGCTGGGGTCTGTACATTATTTGTCACCAGAACAGGCGCGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGATG
GAGATAGTGCTGTTACGATTGCCCTACAGCATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAACGTTCCA
CAAGCATTGGAAAATGTAGTCATCAAGGCAACGGCAAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGCGACGAAGTCAACACCTACTCCTACAAAAGAAGCAGTCAGT
AGTAAGCCTACGCCTAAGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGATATAAAGTTTTGTTATCAGCAGTGGT
TTTAGTCATCGCAGCTCTGGTGGCTTTAGTCTATTTGAGCCCGTCAAATGTAAAAATCCCAGATGTTACTGGAAAAACTA
TTGCCCAAGCACGTTCTGCAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGATTCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCTATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCA
GCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGAT
GCCAAGCTATATCGGCTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAACCCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTC
ACAATCTGATAGCAGCTCAGATAAAACTAGCCCATCCTCTAGCAGTTCGTCAGCTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

• PASTA domain (PASTA) (364-427)

• PASTA domain (PASTA) (505-573)

• PASTA domain (PASTA) (433-500)

• Protein kinase domain (Pkinase) (12-227)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	66.325	93.75	0.622
stkP	Streptococcus pneumoniae D39	65.983	93.75	0.619
stkP	Streptococcus pneumoniae R6	65.983	93.75	0.619
stkP	Streptococcus pneumoniae Rx1	65.812	93.75	0.617
pknB	Streptococcus mutans UA159	59.145	93.75	0.554
stkP/pknB	Streptococcus salivarius strain HSISS4	55.333	96.154	0.532