Detailed information NTG0061902

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SIR_RS17410
• Genome accession: NC_022246
• Coordinates: 1581463..1582530 (-)
• Length: 355 a.a.
• NCBI ID: WP_009569325.1
• Uniprot ID: A0A1L7MWH2
• Organism: Streptococcus intermedius B196
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1576463..1587530

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SIR_RS17390 (SIR_1504)	-	1577098..1578552 (+)	1455	WP_021003164.1	sucrose-6-phosphate hydrolase	-
SIR_RS17395 (SIR_1505)	-	1578533..1579498 (+)	966	WP_021003165.1	LacI family DNA-binding transcriptional regulator	-
SIR_RS17400 (SIR_1506)	-	1579584..1580402 (-)	819	WP_021003166.1	Cof-type HAD-IIB family hydrolase	-
SIR_RS17405 (SIR_1507)	amiF	1580529..1581452 (-)	924	WP_021003167.1	ATP-binding cassette domain-containing protein	Regulator
SIR_RS17410 (SIR_1508)	amiE	1581463..1582530 (-)	1068	WP_009569325.1	ABC transporter ATP-binding protein	Regulator
SIR_RS17415 (SIR_1509)	amiD	1582539..1583465 (-)	927	WP_003074404.1	oligopeptide ABC transporter permease OppC	Regulator
SIR_RS17420 (SIR_1510)	amiC	1583465..1584961 (-)	1497	WP_003074402.1	ABC transporter permease	Regulator
SIR_RS17425 (SIR_1511)	amiA3	1585335..1587314 (-)	1980	WP_021003168.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39608.28 Da
• Isoelectric Point: 4.8594

>NTDB_id=61902 SIR_RS17410 WP_009569325.1 1581463..1582530(-) (amiE) [Streptococcus intermedius B196]
MTQEKNVILTARDIVVEFDVRDKVLTAIRGVSLDLIEGEVLALVGESGSGKSVLTKTFTGMLEDNGRVAQGSINYRGQDL
TKLKSNKDWEPIRGVKIATIFQDPMTSLDPINTIGSQITEVIVKHQKKTAKEAKEMAVDYMNKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIIDLLKSLQQEYQFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYSHLQGDAFALRSDYAMEIDFEEKPPQIYVSDTHWAK
TWLLHENAPKVNKPAVIDDLHEKISSKMGFAHLNA

Nucleotide

• Length: 1068 bp

>NTDB_id=61902 SIR_RS17410 WP_009569325.1 1581463..1582530(-) (amiE) [Streptococcus intermedius B196]
ATGACACAAGAAAAAAATGTAATATTGACTGCTCGCGATATTGTCGTGGAATTTGATGTTCGTGACAAAGTTTTAACAGC
TATTCGGGGCGTTTCGCTTGACCTCATCGAAGGTGAAGTTCTTGCGCTTGTAGGAGAATCTGGTTCTGGTAAGTCCGTTT
TGACAAAAACCTTTACTGGAATGTTAGAGGATAATGGTCGAGTAGCGCAAGGATCGATTAACTATCGTGGACAAGATTTG
ACAAAATTGAAATCCAATAAAGATTGGGAACCTATTCGTGGTGTTAAAATTGCGACAATTTTCCAAGATCCAATGACAAG
TTTAGACCCAATTAATACGATTGGTAGCCAGATTACAGAAGTTATTGTAAAACATCAAAAGAAAACGGCAAAAGAAGCGA
AGGAAATGGCTGTTGACTATATGAATAAAGTAGGTATTCCTGATGCTGAAAAGCGTTTTAATGAGTATCCTTTCCAATAT
TCAGGGGGAATGCGTCAACGGATTGTTATTGCCATTGCACTTGCTTGTCGTCCAGATATTCTAATCTGTGATGAACCTAC
GACAGCACTGGATGTTACCATTCAAGCGCAAATCATTGATTTGTTGAAATCATTGCAACAAGAGTATCAATTCACCACTA
TTTTTATCACCCACGATCTTGGAGTAGTAGCAAGTATTGCGGATAAGGTTGCTGTTATGTATGCTGGAGAAATCGTCGAG
TATGGTACAGTAGAAGAGGTCTTTTATGATCCACGTCATCCGTATACTTGGAGCTTGTTATCAAGCTTACCACAGTTGGC
AGACGATAAAGGGGAGCTGTACTCTATTCCTGGTACGCCACCGTCTCTTTATTCACATTTGCAAGGAGATGCGTTTGCTC
TCCGCTCAGACTATGCGATGGAAATTGATTTTGAGGAAAAACCGCCTCAAATCTATGTATCAGATACGCATTGGGCAAAA
ACATGGTTGCTTCATGAAAATGCTCCAAAAGTGAATAAACCTGCTGTTATTGATGATTTACACGAAAAAATTAGCTCAAA
AATGGGATTTGCCCATTTAAATGCTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A1L7MWH2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	86.441	99.718	0.862
amiE	Streptococcus thermophilus LMG 18311	85.028	99.718	0.848
amiE	Streptococcus thermophilus LMD-9	85.028	99.718	0.848
oppD	Streptococcus mutans UA159	56.25	99.155	0.558