Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SIR_RS16155 Genome accession   NC_022246
Coordinates   1317561..1318244 (+) Length   227 a.a.
NCBI ID   WP_021003029.1    Uniprot ID   T1ZFI1
Organism   Streptococcus intermedius B196     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1312561..1323244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS16125 (SIR_1255) - 1312907..1313191 (-) 285 WP_003073594.1 DUF3165 family protein -
  SIR_RS16130 (SIR_1256) typA 1313254..1315095 (-) 1842 WP_021003026.1 translational GTPase TypA -
  SIR_RS16135 (SIR_1257) - 1315276..1316001 (+) 726 WP_021003027.1 16S rRNA pseudouridine(516) synthase -
  SIR_RS16140 (SIR_1258) - 1316022..1316402 (-) 381 WP_003078427.1 rhodanese-like domain-containing protein -
  SIR_RS16145 - 1316396..1316620 (-) 225 WP_041787497.1 YqgQ family protein -
  SIR_RS16150 (SIR_1259) - 1316883..1317410 (-) 528 WP_021003028.1 Dps family protein -
  SIR_RS16155 (SIR_1260) cclA/cilC 1317561..1318244 (+) 684 WP_021003029.1 prepilin peptidase Machinery gene
  SIR_RS16160 (SIR_1261) - 1318230..1318748 (-) 519 WP_021003030.1 VanZ family protein -
  SIR_RS16165 (SIR_1262) rlmN 1318741..1319823 (-) 1083 WP_021003031.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  SIR_RS16170 (SIR_1263) - 1319857..1320420 (-) 564 WP_004234076.1 YutD family protein -
  SIR_RS16175 (SIR_1264) sepM 1320687..1321742 (-) 1056 WP_003073620.1 SepM family pheromone-processing serine protease Regulator
  SIR_RS16180 (SIR_1265) coaD 1321723..1322220 (-) 498 WP_003078294.1 pantetheine-phosphate adenylyltransferase -
  SIR_RS16185 (SIR_1266) rsmD 1322210..1322749 (-) 540 WP_021003032.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 25616.98 Da        Isoelectric Point: 8.2377

>NTDB_id=61889 SIR_RS16155 WP_021003029.1 1317561..1318244(+) (cclA/cilC) [Streptococcus intermedius B196]
MIHFYFFLVGSIVASFLGLVVDRFPEQSIIVPSSHCNTCGQKLTPRDLVPILSQLINRLRCRFCGEKIPIRYILLELTGG
CLFLVTSLGYLNINQLILLVSGMTLSLYDQRHQEYPLLIWLFSHVLLLFLTGFNLLMAIFLALGILTHFIDLRIGAGDFL
FLASCSAIFNLTEVLLVLQISSIIGLFLFCLKSRKDRLAFIPCLFGASSILILIKFVVFHQNILCLI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=61889 SIR_RS16155 WP_021003029.1 1317561..1318244(+) (cclA/cilC) [Streptococcus intermedius B196]
ATGATTCATTTTTATTTTTTCTTAGTTGGAAGTATTGTAGCTTCCTTTTTAGGACTGGTCGTTGATCGCTTTCCTGAACA
ATCTATTATCGTCCCTTCCAGTCATTGCAATACTTGTGGACAAAAATTAACTCCACGTGATTTAGTCCCTATCCTCTCAC
AACTCATCAATCGTCTACGTTGTCGCTTTTGTGGTGAAAAAATTCCCATCCGCTACATTCTCCTAGAACTAACTGGTGGT
TGTCTCTTTCTTGTAACGTCTTTAGGCTATCTAAACATCAACCAGCTCATCCTGCTTGTATCTGGGATGACCTTATCCCT
TTATGATCAGAGACATCAAGAGTATCCTCTGCTTATTTGGCTATTTTCACATGTCCTTCTTCTCTTTTTAACTGGTTTCA
ATCTTTTGATGGCTATTTTTTTAGCCCTTGGAATTTTAACTCATTTCATTGATTTGCGCATTGGAGCGGGAGATTTTCTT
TTTCTAGCATCCTGTTCAGCGATTTTTAATCTCACAGAAGTTCTCCTTGTTCTTCAAATTTCCAGCATCATCGGCCTGTT
CCTTTTTTGTTTAAAGTCAAGAAAAGACAGGTTAGCATTTATTCCCTGTCTTTTTGGTGCTAGCAGCATTCTGATTTTGA
TAAAATTCGTTGTTTTCCACCAAAATATTTTATGCCTTATTTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-87)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZFI1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

56.744

94.714

0.537
  cclA/cilC Streptococcus mitis NCTC 12261

55.814

94.714

0.529
  cclA/cilC Streptococcus pneumoniae Rx1

55.349

94.714

0.524
  cclA/cilC Streptococcus pneumoniae D39

55.349

94.714

0.524
  cclA/cilC Streptococcus pneumoniae R6

55.349

94.714

0.524
  cclA/cilC Streptococcus pneumoniae TIGR4

54.884

94.714

0.52

Multiple sequence alignment