Detailed information NTG0061890

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SIR_RS16175
• Genome accession: NC_022246
• Coordinates: 1320687..1321742 (-)
• Length: 351 a.a.
• NCBI ID: WP_003073620.1
• Uniprot ID: A0AAD1FJ17
• Organism: Streptococcus intermedius B196
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1315687..1326742

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SIR_RS16140 (SIR_1258)	-	1316022..1316402 (-)	381	WP_003078427.1	rhodanese-like domain-containing protein	-
SIR_RS16145	-	1316396..1316620 (-)	225	WP_041787497.1	YqgQ family protein	-
SIR_RS16150 (SIR_1259)	-	1316883..1317410 (-)	528	WP_021003028.1	Dps family protein	-
SIR_RS16155 (SIR_1260)	cclA/cilC	1317561..1318244 (+)	684	WP_021003029.1	prepilin peptidase	Machinery gene
SIR_RS16160 (SIR_1261)	-	1318230..1318748 (-)	519	WP_021003030.1	VanZ family protein	-
SIR_RS16165 (SIR_1262)	rlmN	1318741..1319823 (-)	1083	WP_021003031.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SIR_RS16170 (SIR_1263)	-	1319857..1320420 (-)	564	WP_004234076.1	YutD family protein	-
SIR_RS16175 (SIR_1264)	sepM	1320687..1321742 (-)	1056	WP_003073620.1	SepM family pheromone-processing serine protease	Regulator
SIR_RS16180 (SIR_1265)	coaD	1321723..1322220 (-)	498	WP_003078294.1	pantetheine-phosphate adenylyltransferase	-
SIR_RS16185 (SIR_1266)	rsmD	1322210..1322749 (-)	540	WP_021003032.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SIR_RS16190 (SIR_1267)	hpf	1322948..1323490 (-)	543	WP_003073626.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
SIR_RS16195 (SIR_1268)	-	1323569..1324234 (-)	666	WP_021003033.1	ComF family protein	-
SIR_RS16200 (SIR_1269)	comFA/cflA	1324231..1325532 (-)	1302	WP_020998970.1	DEAD/DEAH box helicase	Machinery gene
SIR_RS16205 (SIR_1270)	-	1325589..1326224 (+)	636	WP_020998971.1	YigZ family protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38477.49 Da
• Isoelectric Point: 10.2603

>NTDB_id=61890 SIR_RS16175 WP_003073620.1 1320687..1321742(-) (sepM) [Streptococcus intermedius B196]
MKKTRNKFKKWPIVFVVGLVLLFISFVVPLPYYIEVPGSAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFSSSKDLIDYVGSQKIGSKVKVNYVEDGQKKSAIGKIIKLENGKNGIGISLIDRTEVTSSIPIEFSTAGIGGPSAGL
MFSLAIYTQIAEPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEAKKANSKAKTNYETAL
EAAKKIKTKMKIVPVKNLQDAIDYLKRTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=61890 SIR_RS16175 WP_003073620.1 1320687..1321742(-) (sepM) [Streptococcus intermedius B196]
ATGAAAAAAACAAGAAATAAATTTAAAAAATGGCCGATAGTATTTGTGGTAGGGTTGGTCCTTCTTTTTATCTCTTTTGT
AGTTCCTCTGCCTTATTATATTGAAGTACCAGGTAGTGCAGCAGACGTCCGTCAGGTTTTGCGTGTGGATAACAAAGAAG
ATAAGGAAAAAGGTTCTTACAATTTTGTGACAGTTGGGATTCAGCATGCTACCTTTGCTCATTTAGTTTATGCTTGGCTG
ACCCCTTTTACAGATATTTATTCAGCGAAAGATTTGACTGGCGGAACTTCCGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGGTTAAAAAAAGCAGGAAAGGATATCAGCCTGAAATATTTGG
GCGTCTATGTGTTACAAGTTACCAAAAACTCAACCTTTAAGGGCATTTTAAATATTGCAGATACTGTGACAGGTGTGAAT
GATAAGACTTTTAGTAGTTCAAAAGACTTGATTGATTATGTAGGTTCACAGAAGATTGGTAGTAAGGTAAAAGTAAATTA
TGTTGAAGACGGTCAGAAAAAATCTGCTATAGGTAAAATCATCAAACTTGAAAATGGGAAAAATGGAATTGGTATTAGCT
TGATTGACCGGACAGAGGTTACGAGTAGTATACCGATTGAATTCTCAACTGCGGGAATTGGCGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACACAGATTGCTGAACCAACATTAAGAGACGGTAGAAATATTGCTGGTACGGGCTCAAT
TGACCGTGAAGGAAAAGTTGGCGATATTGGAGGCATTGATAAAAAGGTGGTCTCAGCAGCCAAAAATGGTGCAGAAATTT
TCTTTGCACCAAATAATCCAGTCACCAAAGAAGCTAAAAAAGCCAATTCTAAAGCGAAAACAAATTATGAAACAGCTTTG
GAAGCTGCTAAAAAAATTAAAACCAAAATGAAAATTGTACCTGTCAAGAACTTGCAAGATGCTATTGATTACCTCAAACG
CACCAAGAAATCTTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-300)

• PDZ domain (PDZ_2) (133-195)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	63.478	98.291	0.624