Detailed information NTG0061884

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SIR_RS15450
• Genome accession: NC_022246
• Coordinates: 1179839..1180870 (-)
• Length: 343 a.a.
• NCBI ID: WP_021002944.1
• Uniprot ID: T1ZF50
• Organism: Streptococcus intermedius B196
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1174839..1185870

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SIR_RS15430 (SIR_1115)	-	1175645..1176130 (-)	486	WP_009568317.1	LURP-one-related/scramblase family protein	-
SIR_RS15435 (SIR_1116)	prsA	1176355..1177293 (-)	939	WP_003073287.1	peptidylprolyl isomerase PrsA	-
SIR_RS15440 (SIR_1117)	-	1177400..1178083 (-)	684	WP_021002942.1	O-methyltransferase	-
SIR_RS15445 (SIR_1118)	pepF	1178085..1179887 (-)	1803	WP_021002943.1	oligoendopeptidase F	Regulator
SIR_RS15450 (SIR_1119)	coiA	1179839..1180870 (-)	1032	WP_021002944.1	competence protein CoiA	Machinery gene
SIR_RS15455 (SIR_1120)	celB	1180959..1182302 (-)	1344	WP_021002945.1	PTS cellobiose transporter subunit IIC	-
SIR_RS15460 (SIR_1121)	-	1182342..1182848 (-)	507	WP_021002946.1	hypothetical protein	-
SIR_RS15465 (SIR_1122)	-	1182871..1183188 (-)	318	WP_006267580.1	PTS cellobiose transporter subunit IIA	-
SIR_RS15470 (SIR_1123)	-	1183201..1185192 (-)	1992	WP_021002947.1	BglG family transcription antiterminator	-
SIR_RS15475 (SIR_1124)	-	1185248..1185562 (-)	315	WP_009568310.1	PTS cellobiose transporter subunit IIB	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 40445.89 Da
• Isoelectric Point: 9.4248

>NTDB_id=61884 SIR_RS15450 WP_021002944.1 1179839..1180870(-) (coiA) [Streptococcus intermedius B196]
MLIACQENGKLLNAVEDTVNPLDKFLCPACLEAVRFKKGRIMRPHFAHISLKDCHFYTENESAEHLNLKAALFTWARKSN
HAVQVEAYLPKLQQIADLLVEKQIALEVQCSSLSQKRLKDRTDSYHQHVYHVLWLLGKKLWLKDSLTNLQKDFLYFSQNM
GFYLWELDDKKQELRLKYLIHEDLHGRAQYKVQSFPFGQGSLLTVLRTPFQRQEMASFLAKEDKNICRYVRQQLYYQQPK
WMKLQAELYQAGDNLLTKTASDFYPQVHPVCASSFCQIFQDLTPYYQQFSAYYKKAKNKNLQVLYPPIFYAKIFGSIYDR
IGKTEEILWQNKEMKLKKNILGI

Nucleotide

• Length: 1032 bp

>NTDB_id=61884 SIR_RS15450 WP_021002944.1 1179839..1180870(-) (coiA) [Streptococcus intermedius B196]
ATGTTAATAGCTTGTCAGGAAAATGGGAAACTACTAAATGCTGTGGAAGATACAGTAAATCCGCTGGATAAATTTCTCTG
TCCAGCTTGTTTGGAGGCGGTCCGTTTTAAAAAAGGAAGAATCATGCGACCGCATTTTGCTCATATTTCTTTAAAAGACT
GTCATTTTTATACGGAAAATGAAAGCGCAGAACACTTGAATTTGAAAGCTGCTTTGTTTACTTGGGCCAGAAAGTCTAAT
CATGCAGTTCAAGTGGAAGCGTATTTACCTAAATTGCAACAAATTGCAGATCTGTTAGTAGAGAAACAGATTGCGCTTGA
AGTTCAATGCAGTTCACTGAGTCAAAAGCGCTTAAAAGATCGTACAGACAGTTATCATCAACATGTTTATCATGTTCTTT
GGCTATTAGGAAAGAAACTTTGGCTGAAAGATTCTTTAACTAATTTGCAAAAAGATTTTCTTTATTTCAGTCAAAATATG
GGCTTTTATTTATGGGAATTGGATGATAAAAAGCAGGAGCTTCGGCTTAAGTATCTGATTCACGAAGATTTGCATGGCCG
AGCTCAATATAAGGTCCAGTCTTTTCCTTTTGGTCAGGGCAGCCTTTTGACTGTTCTGCGAACGCCCTTTCAACGGCAGG
AGATGGCCAGTTTTTTAGCAAAAGAGGATAAAAATATTTGCCGTTATGTTCGTCAACAGCTCTATTATCAACAACCTAAA
TGGATGAAATTACAGGCAGAATTGTATCAAGCAGGTGATAATTTATTAACCAAAACGGCTAGTGACTTTTATCCGCAGGT
TCATCCGGTTTGTGCCAGCTCTTTCTGTCAAATTTTTCAAGATCTGACTCCTTATTATCAGCAATTTTCAGCTTATTATA
AAAAAGCAAAAAATAAAAATCTACAAGTTCTCTATCCGCCAATTTTTTATGCAAAGATTTTTGGTAGTATTTATGATAGA
ATAGGAAAGACGGAGGAAATTTTATGGCAAAACAAAGAAATGAAATTGAAGAAAAATATACTTGGAATTTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (22-247)

3D structure

• AlphaFold DB: T1ZF50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	53.185	91.545	0.487
coiA	Streptococcus mitis NCTC 12261	53.185	91.545	0.487
coiA	Streptococcus pneumoniae Rx1	52.866	91.545	0.484
coiA	Streptococcus pneumoniae D39	52.866	91.545	0.484
coiA	Streptococcus pneumoniae R6	52.866	91.545	0.484
coiA	Lactococcus lactis subsp. cremoris KW2	44.136	94.461	0.417