Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   SIR_RS15445 Genome accession   NC_022246
Coordinates   1178085..1179887 (-) Length   600 a.a.
NCBI ID   WP_021002943.1    Uniprot ID   T1ZE23
Organism   Streptococcus intermedius B196     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1173085..1184887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS15430 (SIR_1115) - 1175645..1176130 (-) 486 WP_009568317.1 LURP-one-related/scramblase family protein -
  SIR_RS15435 (SIR_1116) prsA 1176355..1177293 (-) 939 WP_003073287.1 peptidylprolyl isomerase PrsA -
  SIR_RS15440 (SIR_1117) - 1177400..1178083 (-) 684 WP_021002942.1 O-methyltransferase -
  SIR_RS15445 (SIR_1118) pepF 1178085..1179887 (-) 1803 WP_021002943.1 oligoendopeptidase F Regulator
  SIR_RS15450 (SIR_1119) coiA 1179839..1180870 (-) 1032 WP_021002944.1 competence protein CoiA Machinery gene
  SIR_RS15455 (SIR_1120) celB 1180959..1182302 (-) 1344 WP_021002945.1 PTS cellobiose transporter subunit IIC -
  SIR_RS15460 (SIR_1121) - 1182342..1182848 (-) 507 WP_021002946.1 hypothetical protein -
  SIR_RS15465 (SIR_1122) - 1182871..1183188 (-) 318 WP_006267580.1 PTS cellobiose transporter subunit IIA -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69238.57 Da        Isoelectric Point: 4.7150

>NTDB_id=61883 SIR_RS15445 WP_021002943.1 1178085..1179887(-) (pepF) [Streptococcus intermedius B196]
MAKQRNEIEEKYTWNLTTIFPTDEAFEMELAQVSKELKEASHLAGHLLDSADSLLKTTAIQMDLMRRIEKLYSYAHMKND
QDTRVAKYQEYQAKGMAIYSEFGQVFAFYEPEFMAITDEQYQAFLAEKPELQVYQHFFDKLLQKKPHILSQREEELLAGA
GEIFSAAGDTFGILDNADIVFPIVHDEEGNEVQLTHGNYISLVEAKNRTVRKEAYEALYSVYEQYQHTYAKTLQTNVKVH
NYNAKVRKFSSAREAALSANFIPESVYESLVSAVNKHLPLLHRYVQLRAKILGISDLKMYDVYTPLSEVDYKFTYEAALT
KAEEVLAILGDDYLNRVKKAFSERWIDVCENQGKRSGAYSGGSYDTNAFMLLNWQDTLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVDDDQTRFAILNHFLDGFRGTVFRQTQFAEFEHAIHKADQEGQVLTSEF
LNDLYADLNEKYYGLTKEDNPQIQYEWARIPHFYYDYYVFQYATGFSAASALADKIVNGTQEDKEKYLHYLKAGNSDYPL
NVIKKAGVDMEKEDYLNAAFAVFERRLDEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=61883 SIR_RS15445 WP_021002943.1 1178085..1179887(-) (pepF) [Streptococcus intermedius B196]
ATGGCAAAACAAAGAAATGAAATTGAAGAAAAATATACTTGGAATTTAACAACGATTTTCCCAACAGATGAAGCGTTTGA
AATGGAATTAGCGCAAGTTTCAAAGGAATTAAAAGAAGCTAGTCATTTAGCAGGTCATCTTTTGGATTCAGCCGATAGCC
TTTTAAAAACGACAGCCATCCAAATGGATTTAATGCGTCGCATTGAAAAGCTCTATTCTTATGCTCACATGAAAAATGAC
CAAGATACGCGTGTGGCAAAATATCAAGAGTATCAAGCTAAGGGCATGGCTATTTATAGCGAGTTCGGGCAGGTGTTTGC
TTTCTATGAGCCAGAATTTATGGCAATTACAGATGAACAGTACCAGGCTTTCTTAGCTGAAAAACCTGAATTGCAAGTCT
ATCAGCACTTCTTTGACAAGTTATTGCAAAAGAAACCTCACATCCTTTCTCAACGTGAGGAAGAATTGTTGGCAGGTGCT
GGTGAAATTTTTAGTGCCGCTGGTGATACTTTTGGAATTTTGGATAATGCCGATATCGTCTTTCCAATTGTACATGACGA
GGAAGGCAATGAAGTACAATTAACGCATGGAAATTACATTAGCTTAGTGGAGGCAAAAAATCGTACAGTCCGTAAGGAAG
CTTATGAAGCACTTTATAGTGTTTATGAGCAATATCAACATACTTATGCTAAGACACTTCAAACAAATGTTAAAGTGCAT
AATTACAACGCAAAAGTACGTAAGTTTTCTTCAGCACGCGAAGCAGCCTTGTCTGCTAACTTTATTCCAGAAAGTGTTTA
TGAGAGTTTGGTGTCTGCAGTCAACAAACATTTACCACTCTTACATCGCTATGTTCAGTTACGAGCTAAGATTTTAGGCA
TTTCAGATCTCAAGATGTATGACGTTTATACACCGCTATCAGAGGTAGATTATAAATTTACCTATGAAGCAGCTTTGACG
AAAGCGGAAGAAGTTTTAGCAATTCTTGGAGATGATTATCTTAACCGAGTGAAAAAAGCCTTTTCAGAGCGTTGGATTGA
TGTTTGTGAGAATCAAGGTAAACGGTCAGGAGCTTATTCTGGTGGCTCTTACGATACTAATGCTTTTATGTTGCTGAATT
GGCAAGATACCTTAGATAATCTCTTCACCTTGGTTCATGAAACGGGGCATAGTATGCATTCTAGCTATACTCGTGAAACA
CAGCCTTATGTTTATGGTGATTATTCTATTTTCTTAGCTGAGATTGCTTCTACTACCAATGAAAATATACTGACGGAGAA
ATTATTGGAAGAAGTAGATGACGATCAAACTCGTTTTGCGATTCTGAATCATTTCTTGGATGGCTTCCGCGGAACTGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAGCATGCTATCCATAAGGCTGATCAAGAAGGTCAAGTCTTAACTAGTGAATTT
TTGAATGATTTATACGCAGATTTGAATGAAAAATATTATGGCTTGACGAAAGAAGATAATCCACAAATTCAATATGAATG
GGCACGGATTCCGCATTTTTACTATGACTATTATGTATTTCAATATGCGACTGGTTTTTCAGCAGCATCTGCTTTAGCTG
ATAAAATTGTCAATGGAACACAAGAAGATAAAGAGAAATATCTCCATTATCTCAAAGCAGGAAATTCTGATTATCCGCTG
AATGTCATTAAAAAAGCTGGTGTTGATATGGAAAAAGAAGACTATCTCAATGCTGCCTTTGCAGTCTTTGAACGTCGTCT
TGATGAATTTGAAGCACTTGTAGAAAAGTTAGGCTTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZE23

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

68.624

99.333

0.682

Multiple sequence alignment