Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SAIN_RS02755 Genome accession   NC_022244
Coordinates   551611..553761 (+) Length   716 a.a.
NCBI ID   WP_003025436.1    Uniprot ID   A0AAP6BMV2
Organism   Streptococcus anginosus C1051     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 546611..558761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAIN_RS02730 (SAIN_0532) frr 547141..547698 (+) 558 WP_003034284.1 ribosome recycling factor -
  SAIN_RS02735 (SAIN_0533) cvfB 548045..548899 (+) 855 WP_003025448.1 RNA-binding virulence regulatory protein CvfB -
  SAIN_RS02740 (SAIN_0534) holA 548980..550017 (+) 1038 WP_021001445.1 DNA polymerase III subunit delta -
  SAIN_RS02745 (SAIN_0535) - 550088..550693 (+) 606 WP_021001446.1 superoxide dismutase -
  SAIN_RS02750 (SAIN_0536) - 550756..551130 (-) 375 WP_037590248.1 hypothetical protein -
  SAIN_RS02755 (SAIN_0537) comA/nlmT 551611..553761 (+) 2151 WP_003025436.1 peptide cleavage/export ABC transporter Regulator
  SAIN_RS02760 (SAIN_0538) - 553772..555133 (+) 1362 WP_021001448.1 bacteriocin secretion accessory protein -
  SAIN_RS02765 (SAIN_0539) - 555226..555375 (+) 150 WP_003025431.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SAIN_RS02770 (SAIN_0540) - 555420..556727 (-) 1308 WP_021001449.1 sensor histidine kinase -
  SAIN_RS02775 (SAIN_0541) comE/blpR 556732..557478 (-) 747 WP_037590320.1 response regulator transcription factor Regulator
  SAIN_RS02780 (SAIN_0542) - 557647..558360 (-) 714 WP_021001450.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80424.99 Da        Isoelectric Point: 9.4752

>NTDB_id=61754 SAIN_RS02755 WP_003025436.1 551611..553761(+) (comA/nlmT) [Streptococcus anginosus C1051]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLTSFLPLI
FKQRSLIFYIVLASLLVTLINIVSSYYLQGILDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIILSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLFILIMVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEETRYQKIDSEFVNYLDKSFTLSKYSIMQTSLKQGAQFI
LNVVILWVGASLAMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQVITEKNFLA
GDITFHDVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILANLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHTKLMERKGFYHHLFSK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=61754 SAIN_RS02755 WP_003025436.1 551611..553761(+) (comA/nlmT) [Streptococcus anginosus C1051]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACTAAGATATCAAAAGAGACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAGAATGGGCTTACTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTTGTGACCCTCATTAACATTGTTAGTTCTTATTA
TCTGCAAGGGATTTTGGATGAATACATTCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTATACTTAGTCAGCGATTAACCATCGATGTA
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAAATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTTTATTTTGATAA
TGGTAGGAGGGGTACTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACAGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTTATGCAAAGTAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACGATTAAATCTTTAACCAGCGAAGAAACTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCCATTATGCAGACATCTCTCAAACAAGGAGCACAATTTATT
TTGAATGTTGTTATTCTATGGGTTGGAGCATCTCTGGCTATGTCTCAAAAAATTTCGATTGGACAGCTGATTACTTTTAA
TGCACTCCTTTCGTATTTTACAAGTCCACTTGAAAGTATCATCAATCTGCAAACTAAGCTGCAGTCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCATTACAGAGAAAAATTTCTTGGCT
GGTGACATTACTTTTCATGATGTTTCTTATAAATATGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTTAATGGAAATGATCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCCATCTTAGCAAATCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTTTAACTGAGAAAAAGGTCATTGACAATCTGATGGGCTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAAGTGATTGTTCTTGATAAAGGACAGA
TTATTGAAACTGGTTCCCACACTAAATTGATGGAAAGAAAAGGTTTTTATCATCATTTATTTAGCAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(167-437)

ABC transporter (ABC_tran)

(499-648)

Peptidase C39 family (Peptidase_C39)

(6-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.227

99.022

0.705
  comA Streptococcus mitis NCTC 12261

66.245

99.302

0.658
  comA Streptococcus mitis SK321

65.963

99.302

0.655
  comA Streptococcus gordonii str. Challis substr. CH1

65.541

99.302

0.651
  comA Streptococcus pneumoniae D39

65.401

99.302

0.649
  comA Streptococcus pneumoniae R6

65.401

99.302

0.649
  comA Streptococcus pneumoniae Rx1

65.401

99.302

0.649
  comA Streptococcus pneumoniae TIGR4

64.979

99.302

0.645

Multiple sequence alignment