Detailed information NTG0061675

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SANR_RS04795
• Genome accession: NC_022239
• Coordinates: 967321..969549 (+)
• Length: 742 a.a.
• NCBI ID: WP_020999585.1
• Uniprot ID: -
• Organism: Streptococcus anginosus C238
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 962321..974549

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS11130 (SANR_0936)	rpmG	963183..963332 (+)	150	WP_003034401.1	50S ribosomal protein L33	-
SANR_RS04775 (SANR_0937)	secG	963372..963605 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
SANR_RS04780 (SANR_0938)	rnr	963696..966035 (+)	2340	WP_003034491.1	ribonuclease R	-
SANR_RS04785 (SANR_0939)	smpB	965998..966465 (+)	468	WP_003034458.1	SsrA-binding protein SmpB	-
SANR_RS04790 (SANR_0940)	comEA/celA/cilE	966633..967337 (+)	705	WP_020999584.1	helix-hairpin-helix domain-containing protein	Machinery gene
SANR_RS04795 (SANR_0941)	comEC/celB	967321..969549 (+)	2229	WP_020999585.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SANR_RS04800 (SANR_0942)	-	969630..970322 (+)	693	WP_020999586.1	DUF805 domain-containing protein	-
SANR_RS04805 (SANR_0943)	-	970827..971813 (+)	987	WP_003034384.1	Gfo/Idh/MocA family protein	-
SANR_RS04810 (SANR_0944)	-	971835..972488 (+)	654	WP_003034489.1	uracil-DNA glycosylase	-
SANR_RS04815 (SANR_0945)	-	972525..972995 (+)	471	WP_003031692.1	NUDIX hydrolase	-
SANR_RS04820 (SANR_0946)	-	973008..974285 (+)	1278	WP_003034545.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85066.91 Da
• Isoelectric Point: 9.9699

>NTDB_id=61675 SANR_RS04795 WP_020999585.1 967321..969549(+) (comEC/celB) [Streptococcus anginosus C238]
MSQWIKKFPIKPIYIAFLLVWLYFAIYQSSWLGWLGFIFLVIRLFRFYSPKECFMTFMILSCFVGFFFIRREMAERQANA
EPSPVKQIAVLPDTIKVNGDSLSFRGKTNGQTYQVYYKLKSKEEQLAFQNLSSLVILTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHPFEWLSSWRRKALVFIKKHFPNPMSNYMTGLLFGALDTDFDEMNNLYSGLGIIHL
FALSGMQVGFFMEGFRKLLLRLGLTQEMVHKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKIVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDTMMLPGLT
LIFLSSPLIKLTQVNFLFEGLENSIRWLASVFGRPIVFGQPSPLLLIVMLLVLAILYDIRKNKKWVIFLSLLLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGRNVLIDVGGREEIRTKEAWQKRATSSNAEKTLIPYLKSRGIDTIDALVLTNPNP
DYAGDVLEVAKKFAIKKIYISRSSLSNADFLEKLRKINTFIHVVKQGDKLPIFDYHLQVLSGASKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHGAKDSSSSKFLQQIEPTVALISVGKNNQSKQPSQDIIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide

• Length: 2229 bp

>NTDB_id=61675 SANR_RS04795 WP_020999585.1 967321..969549(+) (comEC/celB) [Streptococcus anginosus C238]
ATGTCACAGTGGATTAAAAAATTTCCGATTAAGCCGATTTACATTGCTTTCTTACTCGTCTGGTTATATTTTGCAATCTA
TCAAAGTAGCTGGTTAGGCTGGTTGGGTTTTATCTTTCTGGTGATTCGTCTTTTTCGCTTTTATTCACCAAAAGAATGTT
TCATGACCTTCATGATTCTCTCTTGTTTTGTTGGTTTTTTCTTTATTCGTAGGGAAATGGCAGAGCGGCAAGCAAATGCA
GAACCTTCTCCCGTAAAACAAATAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCACTTTCTTTCCGTGGTAA
AACAAATGGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGTTATATTGACCGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAAGACAGAATCAGCTTGCACCCTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAAAGCACTGGTATTTATCAAGAAGCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACAGACTTCGATGAAATGAACAATCTTTACTCTGGCTTGGGGATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGTTTTCGTAAGTTGCTGTTAAGGTTGGGTCTTACACAGGA
AATGGTCCATAAATGCCAATATCCATTTTCTTTCTTCTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGAAGCT
TAGTTCAGAAATTATTGTCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCTTCCTTTCTTTTAACGGCAGGAGGAGTTCTCTCTTGCGCCTATGCTTTTGTTATTAGTGTGATAGATTTTGAAAG
TCTGACTTCTTGGCGAAAGATTGTTGTAGAGAGCAGTGTCATTTCGCTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTAATTTTCGATACAATGATGCTGCCAGGCTTGACG
TTGATTTTTCTTTCTTCGCCTTTGATAAAGCTAACTCAGGTCAATTTTCTATTTGAAGGGTTAGAAAATAGCATTCGTTG
GCTAGCAAGTGTCTTTGGCAGACCAATCGTTTTTGGGCAACCCAGTCCGCTTTTGCTGATTGTTATGCTACTTGTACTGG
CTATTTTGTATGATATTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGCTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCCTTGCAAAATGAGATCACAATGGTTGATGTTGGGCAGGGAGATAGTATTTTTCTGAGAGACTGGAAAGGACG
AAATGTATTGATTGATGTTGGGGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCGACTAGCTCAAATG
CAGAGAAAACTTTGATTCCTTACTTAAAAAGTCGTGGCATAGATACGATTGATGCTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAATTTGCAATAAAGAAAATTTATATTTCCAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAAATAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATTATCATTTGCAAGTTCTTTCGGGTGCTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCGAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGGAGCCAAGGACTCATCAAGTTCAAAATTTTTACAACAAATAGAACCAACGGTCGCTCTCATTT
CTGTTGGGAAAAATAATCAATCTAAGCAACCAAGTCAAGATATAATAGAGCGATTTGCACAATTGCCTGCTAAGGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-592)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (216-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.615	100	0.561
comEC/celB	Streptococcus mitis NCTC 12261	54.886	100	0.553
comEC/celB	Streptococcus pneumoniae TIGR4	54.545	100	0.55
comEC/celB	Streptococcus pneumoniae Rx1	53.61	100	0.54
comEC/celB	Streptococcus pneumoniae D39	53.61	100	0.54
comEC/celB	Streptococcus pneumoniae R6	53.61	100	0.54
comEC	Lactococcus lactis subsp. cremoris KW2	47.383	100	0.476