Detailed information NTG0061664

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SANR_RS03015
• Genome accession: NC_022239
• Coordinates: 590391..591422 (+)
• Length: 343 a.a.
• NCBI ID: WP_003037510.1
• Uniprot ID: I0SBF6
• Organism: Streptococcus anginosus C238
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 585391..596422

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS02990	-	585464..585778 (+)	315	WP_003037418.1	PTS cellobiose transporter subunit IIB	-
SANR_RS02995 (SANR_0586)	-	585834..587825 (+)	1992	WP_020999517.1	BglG family transcription antiterminator	-
SANR_RS03000 (SANR_0587)	-	587838..588155 (+)	318	WP_003037503.1	PTS cellobiose transporter subunit IIA	-
SANR_RS03005 (SANR_0588)	-	588179..588685 (+)	507	WP_041791070.1	hypothetical protein	-
SANR_RS03010 (SANR_0589)	celB	588725..590068 (+)	1344	WP_003037415.1	PTS cellobiose transporter subunit IIC	-
SANR_RS03015 (SANR_0590)	coiA	590391..591422 (+)	1032	WP_003037510.1	competence protein CoiA	Machinery gene
SANR_RS03020 (SANR_0591)	pepF	591374..593176 (+)	1803	WP_003037368.1	oligoendopeptidase F	Regulator
SANR_RS03025 (SANR_0592)	-	593178..593861 (+)	684	WP_003037234.1	O-methyltransferase	-
SANR_RS03030 (SANR_0593)	prsA	593968..594906 (+)	939	WP_003037344.1	peptidylprolyl isomerase PrsA	-
SANR_RS03035 (SANR_0594)	-	595044..595613 (+)	570	WP_080553209.1	LURP-one-related/scramblase family protein	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 40832.11 Da
• Isoelectric Point: 9.2445

>NTDB_id=61664 SANR_RS03015 WP_003037510.1 590391..591422(+) (coiA) [Streptococcus anginosus C238]
MLMACQENGKILNAVEDTVNPLDRFLCPSCKEAVRFKNGKVMRPHFAHISLKECHFYTENESAEHLNLKAVLFTWARKSN
HAIQVEAYLPELQQIADLLVEKQIVLEVQCSSLSQKRLKERTESYRQHGYRVLWLLGKKLWLKNTLTNLQKDFLYFSQNM
GFHMWELDEQKQLLRLKYLIHEDLHGKVQYKEKSFAFGKGNLLDIFRQPFCKQEMTSFLAKEDKNICSYVRQQLYYQQPK
WMKWQAELYQTGDNLLTKTASDFYPQVQPVRSSSFCQIFQDLTPYYQQFSAYYEKEKNKNLQILYPPAFYAKIFGNIYDR
IGRTEEILWQNKEMKLKKNTLGT

Nucleotide

• Length: 1032 bp

>NTDB_id=61664 SANR_RS03015 WP_003037510.1 590391..591422(+) (coiA) [Streptococcus anginosus C238]
ATGTTAATGGCTTGTCAGGAAAACGGAAAAATACTAAATGCTGTGGAAGATACGGTAAATCCGTTGGATAGGTTTCTCTG
CCCGTCTTGTAAGGAAGCGGTGCGATTTAAGAATGGCAAGGTGATGCGACCGCACTTTGCTCATATTTCTTTAAAAGAAT
GTCATTTTTATACGGAAAATGAAAGTGCAGAACACTTAAATCTGAAAGCTGTTTTGTTTACTTGGGCTAGAAAGTCCAAT
CATGCGATTCAAGTGGAAGCATATTTACCAGAATTGCAGCAAATCGCAGATTTGTTAGTTGAAAAACAAATTGTGCTTGA
AGTTCAGTGTAGCTCACTTAGTCAAAAACGCTTAAAAGAGCGTACGGAAAGTTATCGTCAGCATGGCTATCGCGTTCTTT
GGCTCTTGGGAAAGAAACTTTGGCTGAAAAATACTTTGACCAATTTACAAAAGGATTTTCTCTATTTCAGTCAAAATATG
GGCTTTCATATGTGGGAATTGGACGAACAAAAACAGCTTTTGAGGCTTAAATACTTGATTCATGAAGATTTGCATGGCAA
GGTTCAGTATAAGGAGAAAAGTTTTGCTTTTGGTAAAGGAAACCTTTTAGACATCTTTCGTCAGCCATTCTGCAAGCAGG
AAATGACGAGTTTTCTGGCAAAAGAAGATAAAAATATTTGCAGTTATGTGCGCCAGCAGCTCTACTATCAGCAGCCCAAA
TGGATGAAATGGCAGGCAGAATTGTATCAAACGGGTGATAATTTATTAACCAAAACGGCTAGTGACTTTTATCCGCAAGT
CCAACCTGTTCGTTCCAGCTCTTTCTGTCAGATTTTTCAGGATCTCACGCCTTATTACCAGCAATTTTCAGCTTATTATG
AAAAAGAAAAAAATAAAAATCTTCAAATTCTCTATCCTCCAGCTTTTTATGCAAAGATTTTTGGCAATATTTATGATAGA
ATAGGAAGGACGGAGGAAATTTTATGGCAAAACAAAGAAATGAAATTGAAGAAAAATACACTTGGGACCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (2-252)

3D structure

• AlphaFold DB: I0SBF6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	53.503	91.545	0.49
coiA	Streptococcus pneumoniae Rx1	52.866	91.545	0.484
coiA	Streptococcus pneumoniae D39	52.866	91.545	0.484
coiA	Streptococcus pneumoniae R6	52.866	91.545	0.484
coiA	Streptococcus pneumoniae TIGR4	52.548	91.545	0.481
coiA	Lactococcus lactis subsp. cremoris KW2	45.062	94.461	0.426